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Chinese and western medicine composition for treating epilepsy as well as preparation method and application thereof

A technology for Chinese and Western medicine and epilepsy, applied in the field of medicine, can solve the problems of strong dependence on combination of Chinese and Western medicine, unable to completely cure epilepsy, difficult for patients to accept, etc., and achieve the effects of low price, enhanced immune function, and low dosage.

Inactive Publication Date: 2017-05-10
郑州莉迪亚医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such as carbamazepine, yingal, epileptamine, etc., not only cannot completely cure epilepsy, but also fail to achieve the purpose of treatment, and its side effects are large, and the combination of Chinese and Western medicine is highly dependent, resulting in unavoidable problems such as mental depression, IQ, and mental retardation. Side effects, so not easily accepted by patients
In addition, often taking anti-epileptic western medicine, it is easy to lead to the adaptation of the combination of Chinese and western medicine. If you want to maintain a certain curative effect, you have to increase the dose, forming a vicious circle
Traditional Chinese medicine is effective in treating epilepsy with few side effects, but the treatment cycle is long and the reduction is slow, which is not conducive to the recovery of patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] In the embodiment of the present invention, a Chinese and Western medicine combination for treating epilepsy is composed of the following raw materials in parts by weight: 1 part of safflower glycoside, 6 parts of nobietin, 11 parts of rubyricol ester, and 15 parts of anisodamine.

[0019] Anisodamine was mixed with 10.8 times the mass of deionized water to prepare anisodamine solution. Mix and grind nobietin and ruberetin ester, add anisodamine solution, and stir at 52°C for 30 minutes to prepare mixture A. The mixture A was ultrasonically treated for 20 minutes at a temperature of 45°C, with an ultrasonic power of 700W, then added safflower glycosides, and subjected to microwave treatment for 3 minutes, with a microwave power of 800W, then stirred at a temperature of 63°C until dry, and then granulated. A combination of Chinese and Western medicine.

Embodiment 2

[0021] In an embodiment of the present invention, a Chinese and Western medicine combination for treating epilepsy is composed of the following raw materials in parts by weight: 5 parts of safflower glycosides, 14 parts of nobietin, 19 parts of ruberetin, and 23 parts of anisodamine.

[0022] Anisodamine was mixed with 10.8 times the mass of deionized water to prepare anisodamine solution. Mix and grind nobiletin and ruberetin ester, add anisodamine solution, and stir at 52°C for 33 minutes to prepare mixture A. The mixture A was ultrasonically treated for 20 minutes at a temperature of 45°C, with an ultrasonic power of 700W, then added safflower glycosides, and subjected to microwave treatment for 3 minutes, with a microwave power of 800W, then stirred at a temperature of 63°C until dry, and then granulated. A combination of Chinese and Western medicine.

Embodiment 3

[0024] In an embodiment of the present invention, a Chinese and Western medicine combination for treating epilepsy is composed of the following raw materials in parts by weight: 2 parts of safflower glycosides, 8 parts of nobietin, 13 parts of ruberetin, and 17 parts of anisodamine.

[0025] Anisodamine was mixed with 10.8 times the mass of deionized water to prepare anisodamine solution. Mix and grind nobiletin and rhucitol ester, add anisodamine solution, and stir at 52°C for 31 minutes to prepare mixture A. The mixture A was ultrasonically treated for 20 minutes at a temperature of 45°C, with an ultrasonic power of 700W, then added safflower glycosides, and subjected to microwave treatment for 3 minutes, with a microwave power of 800W, then stirred at a temperature of 63°C until dry, and then granulated. A combination of Chinese and Western medicine.

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Abstract

The invention discloses a Chinese and western medicine composition for treating epilepsy as well as a preparation method and application thereof. The Chinese and western medicine composition comprises the following raw materials in parts by weight: 1-5 parts of carthamin, 6-14 parts of nobiletin, 11-19 parts of cuscohygrine and 15-23 parts of anisodamine. The preparation method comprises the following steps: mixing and grinding nobiletin and cuscohygrine, adding anisodamine solution, stirring at the temperature of 52 DEG C for 30-33min, ultrasonically processing at the temperature of 45 DEG C for 20 min at the ultrasonic power of 700W, then adding carthamin, processing for 3min with microwaves at the microwave power of 800W, stirring at the temperature of 63 DEG C until the solution is dry, and pelleting, so as to obtain the Chinese and western medicine composition. The Chinese and western medicine composition disclosed by the invention is used for treating epilepsy and has the purpose of treating symptoms and causes; the Chinese and western medicine composition has quick effect and good long-term effect, and the disease is not easy to recur. The Chinese and western medicine composition disclosed by the invention has the advantages of small dosage, no toxicity or side effect, no anaphylaxis, high cure rate, low recurrence rate and low cost, so that patients accept the Chinese and western medicine composition easily.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a Chinese and Western medicine combination for treating epilepsy, a preparation method and application thereof. Background technique [0002] Epilepsy, also commonly known as lamb's wind, is a chronic brain disorder caused by a variety of etiologies. It is a chronic disease in which the sudden abnormal discharge of brain neurons leads to transient brain dysfunction. It manifests as disturbance of consciousness with sudden onset and sudden cessation, body convulsions, foaming at the mouth, body convulsions, eyes turned up, and normal people after waking up. There are many causes of epilepsy, common causes include poisoning, hypoxia, trauma, infection, brain disease, congenital disease, metabolic disease, heart and cerebrovascular disease, etc. [0003] Western medicine and western medicine have its advantages in controlling epileptic seizures, but too strong inhibitory effect wi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7034A61K31/46A61K31/352A61K31/4025A61P25/08
CPCA61K31/7034A61K31/352A61K31/4025A61K31/46A61K2300/00
Inventor 不公告发明人
Owner 郑州莉迪亚医药科技有限公司
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