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Radix ranunculus ternate traditional Chinese medicine combination and preparation method and application thereof

The technology of cat's claw and composition is applied in the field of cat's claw traditional Chinese medicine composition and preparation thereof, which can solve the problems of easy occurrence of side effects and the like, achieve good anti-inflammatory effect, simple preparation process, and improve the effect of anti-inflammatory effect.

Active Publication Date: 2017-03-29
TONGDE HOSPITAL OF ZHEJIANG PROVINCE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned drugs are prone to side effects while anti-inflammatory, such as upper gastrointestinal bleeding caused by gastric and duodenal ulcers, lethargy, trance, depression, platelet aggregation, liver toxicity, allergic reactions, etc.

Method used

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  • Radix ranunculus ternate traditional Chinese medicine combination and preparation method and application thereof
  • Radix ranunculus ternate traditional Chinese medicine combination and preparation method and application thereof
  • Radix ranunculus ternate traditional Chinese medicine combination and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Grind cat's claw, sieve with 60 meshes, heat and reflux with 6 to 8 times the volume of 85% ethanol to extract twice, each time for 3 hours, collect and combine the extracts and concentrate, dry to obtain cat's claw extract, cat's claw The mass percent content of total saponins in the grass extract is 50%-70%.

[0030] Beat the propolis into pieces, add equal weight of starch, pulverize with a pulverizer, and sieve through 80 mesh to obtain propolis powder with a particle size of less than 80 mesh. The mass percentage of total flavonoids in the propolis powder is 8% to 15%.

[0031] Crush Centella asiatica, sieve through a 60-mesh sieve, heat and reflux with 8 to 10 times the volume of 75% ethanol to extract twice for 1 hour each time, collect the combined extracts and concentrate, dry to obtain Centella asiatica extract, Centella asiatica The mass percentage content of the total saponins in the grass is 50%-70%.

[0032] Mix cat's claw extract, propolis powder, and ce...

Embodiment 2

[0034]The cat's claw is crushed, sieved with a 60 mesh, and extracted twice with 6-8 times the volume of 85% ethanol, 3 hours each time, and the combined extract is collected, concentrated, and dried to obtain the cat's claw extract, the cat's claw. The mass percentage content of total saponins in the grass extract is 30% to 50%.

[0035] The propolis is smashed into pieces, the starch of equal weight is added, pulverized with a pulverizer, and sieved with 80 meshes to obtain a propolis powder with a particle diameter less than 80 meshes, and the mass percentage of total flavonoids in the propolis powder is 8% to 15%.

[0036] Pulverize the Centella asiatica, sieve with 60 mesh, and extract twice with 8 to 10 times the volume of 75% ethanol by heating and refluxing for 1 hour each time. The mass percentage of total saponins in the grass is 30% to 50%.

[0037] The cat's claw extract, propolis powder, and centella asiatica extract are uniformly mixed in a mass ratio of 6:2:2, ...

Embodiment 3

[0039] The cat's claw is crushed, sieved with a 60 mesh, and extracted twice with 6-8 times the volume of 85% ethanol, 3 hours each time, and the combined extract is collected, concentrated, and dried to obtain the cat's claw extract, the cat's claw. The mass percentage content of total saponins in the grass extract is 50% to 70%.

[0040] The propolis is smashed into pieces, the starch of equal weight is added, pulverized with a pulverizer, and sieved with 80 meshes to obtain a propolis powder with a particle diameter less than 80 meshes, and the mass percentage of total flavonoids in the propolis powder is 8% to 15%.

[0041] Pulverize the Centella asiatica, sieve with 60 mesh, and extract twice with 8 to 10 times the volume of 75% ethanol by heating and refluxing for 1 hour each time. The mass percentage of total saponins in the grass is 30% to 50%.

[0042] The cat's claw extract, propolis powder, and centella asiatica extract are uniformly mixed in a mass ratio of 5:3:2,...

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Abstract

The invention provides a radix ranunculus ternate traditional Chinese medicine combination. The radix ranunculus ternate traditional Chinese medicine combination is composed of radix ranunculus ternate extract and propolis, wherein the mass ratio of the radix ranunculus ternate extract to the propolis to centella asiatica extract is 3-6:4-1:4-1. Under the synergistic interaction of radix ranunculus ternate, the propolis and centella asiatica, the combination can achieve an effective anti-inflammatory action. The invention further provides application of the radix ranunculus ternate traditional Chinese medicine combination in preparation of anti-inflammatory therapeutic drugs. The invention further provides a preparation method of the radix ranunculus ternate traditional Chinese medicine combination. The preparation method includes the steps that (1) the propolis is diced, starch with the same weight as the propolis is added, the propolis and the starch are pulverized through a pulverizer and subjected to 80-mesh screening, and propolis powder is obtained; and (2) the radix ranunculus ternate extract, the propolis powder and the centella asiatica extract are evenly mixed according to the mass ratio of 3-6:4-1:4-1 and subjected to 80-mesh screening, and the radix ranunculus ternate traditional Chinese medicine combination is obtained. The preparation process is simple and suitable for industrial production.

Description

technical field [0001] The invention relates to the field of pharmaceutical compositions, in particular to a cat's claw traditional Chinese medicine composition and its preparation method and application. Background technique [0002] Inflammation is the defense response of living tissue with vascular system to damage factors, and is a defense response of the body to stimulation, manifested as redness, swelling, heat, pain and dysfunction. Vascular responses are central to the inflammatory process. Inflammation can be infectious inflammation caused by infection, or non-infectious inflammation not caused by infection. The response of inflammation to the damaged local tissue of the body is called inflammatory response, which can be divided into acute and chronic according to the duration; from the main tissue changes, it can be divided into degenerative inflammation, exudative inflammation, proliferative inflammation and specific inflammation. inflammation. The basic pathol...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61P29/00A61K35/644
CPCA61K35/644A61K36/23A61K36/71A61K2300/00
Inventor 童晔玲杨锋任泽明陈璇戴关海
Owner TONGDE HOSPITAL OF ZHEJIANG PROVINCE
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