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Carrier systems for water-soluble active ingredients

An active component, water-soluble technology, applied in the field of sunscreen compositions of water-in-silicone inverse emulsions, can solve the problems of difficulty in formulating long-term stability of optical filters, lack of stability, etc.

Active Publication Date: 2020-03-03
LOREAL SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the problem is that such filters are difficult to formulate with them when considering long-term stability due to their electrolytic properties
This lack of stability often manifests itself as recrystallization of the filter in the composition, causing it to separate from the emulsion

Method used

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  • Carrier systems for water-soluble active ingredients
  • Carrier systems for water-soluble active ingredients
  • Carrier systems for water-soluble active ingredients

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0064] The preparation methods for each of the examples provided in Tables 1 and 2 were substantially the same. The examples in Tables 1 and 2 include inventive examples of emulsions incorporating high concentrations of water-soluble active ingredients and having water-releasing effects. The examples in Tables 3 and 4 are comparative examples illustrating the lack of emulsion stability and / or stabilization of active ingredients in typical water-in-oil emulsions.

[0065] In each example (inventive example and comparative example), the viscosity of the emulsion was measured using a Brookfield viscometer using a Helipath spindle T-D with a speed set at 10 rpm. The spindle is oscillated in the test sample and the measurement is taken after one minute.

[0066] The water release effect of each example was measured by placing about 0.2 g of the cosmetic composition on the back of the hand and then applying it by gently swirling with the middle and ring fingers of the other hand. ...

Embodiment 13-17

[0087]

[0088]

[0089] In preparing each of the examples in Table 5, the following method was used.

[0090] The components of Phase B (aqueous phase) were mixed together in a side beaker with a rotor / stator stirrer until all solids dissolved, forming a clear solution. If desired, Phase B (aqueous phase) can be heated slowly to about 40-45°C until all solids are dissolved. The ingredients of phase A (oil phase) were placed in the main beaker and mixed well with a propeller stirrer at about 600-700 RPM, then set aside. Slowly add the mixture of water phase (Phase B) ingredients to the combined Phase A (oil phase) ingredients and mix using a propeller mixer for 10-15 minutes for batches of about 1 kg. As the viscosity of the mixture increased, the stirring rate was increased from 700 rpm to about 1200 rpm. As the water phase is mixed into the oil phase, a water-in-oil emulsion forms. Optionally, powder is added to the batch and mixed into the water-in-oil emulsion.

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PUM

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Abstract

A water-releasing composition in the form of an emulsion and process for using the composition are provided. The composition includes an aqueous phase and an oil phase. The aqueous phase includes at least one water-soluble active ingredient at a concentration by weight of from about 0.1% to about 20%>, based upon weight of the composition. The oil phase includes dimethicone at a concentration by weight of about 1% to about 25%, and an emulsifying crosslinked siloxane elastomer at a concentration by weight of about 0.1% to about 20%, both based upon weight of the composition. The composition has a phase ratio of the aqueous phase to the oil phase of about 3.0 to about 12.0. The composition converts from an emulsion to a plurality of droplets upon application of shear.

Description

technical field [0001] The present invention relates to compositions comprising water-soluble active ingredients and methods of their use. More specifically, the present invention relates to compositions in the form of emulsions having an aqueous phase comprising at least one water-soluble active ingredient and an oil phase comprising dimethicone and an emulsified crosslinked silicone elastomer . In addition, the present invention relates to sunscreen compositions of water-in-silicone inverse emulsions comprising high levels of water-soluble UV filters. The composition is capable of carrying large quantities of water-soluble components in a texturally pleasing manner without undergoing emulsion separation. The invention also provides a water-releasing effect when applied to keratinous substrates such as skin, hair or nails. The water release effect allows the composition, initially in the form of an emulsion, to transform into a plurality of liquid droplets upon application...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/891A61K8/894A61K8/06A61Q17/04A61Q19/08
CPCA61K8/064A61K8/891A61K8/894A61Q17/04A61Q19/08
Inventor C.邱潘志A.加尔迪L.曼宁A.B.戈德堡
Owner LOREAL SA
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