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Functional peptide with cosmetic efficacy and preparation method and application thereof

A technology of functional peptides and efficacy, which is applied in the field of functional peptides with cosmetic efficacy and its preparation, which can solve the problems of inconspicuous improvement of aging, limited amount of product addition, high processing cost, etc., achieve obvious anti-wrinkle effect and increase water content And collagen content, the effect of low production cost

Active Publication Date: 2017-03-22
广州精准健康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these methods can all play anti-aging effects to a certain extent, due to the high processing cost, the amount of addition in the product is limited, the products with good effect are often very expensive, and the improvement of general products on aging is not outstanding.

Method used

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  • Functional peptide with cosmetic efficacy and preparation method and application thereof
  • Functional peptide with cosmetic efficacy and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] A method for preparing functional peptides with cosmetic efficacy, comprising the following steps:

[0046] (1) Wash the bovine neck ligament and grind it through a meat grinder. Add 5% NaCl solution twice the weight of the bovine ligament and incubate at 40°C for 5 hours, pass through a 200-mesh vibrating sieve, and take the retentate; wash the retentate with deionized water several times and filter through a 200-mesh vibrating sieve until the NaCl in the retentate The content of sodium chloride is below 0.5%; add 0.5% NaOH solution of 1 times its mass to the retentate after washing, stir at 95°C for 1 hour, use an oil-water separator for centrifugation, take the precipitate, and wash it with deionized water several times , filtered through a vibrating sieve, washed the precipitate with water until neutral, and obtained a crude elastin extract.

[0047] (2) Add 1.0% NaOH solution 5 times its mass to the fish skin and soak for 2 hours at room temperature; remove the fl...

Embodiment 2

[0053] A method for preparing functional peptides with cosmetic efficacy, comprising the following steps:

[0054] (1) Wash the bovine neck ligament and grind it through a meat grinder. Add 5% NaCl solution with 1 times the mass of bovine ligament and keep warm at 50°C for 4 hours, pass through a 200-mesh vibrating sieve, and take the retentate; wash the retentate with deionized water several times and filter through a 200-mesh vibrating sieve until the NaCl in the retentate The content of sodium chloride is below 0.5%; add 0.5% NaOH solution twice its mass to the retentate after washing, stir at 85°C for 2 hours, use an oil-water separator for centrifugation, take the precipitate, and wash it with deionized water several times , filtered through a vibrating sieve, washed the precipitate with water until neutral, and obtained a crude elastin extract.

[0055] (2) Add 1.0% NaOH solution 3 times its mass to the fish skin and soak for 3 hours at room temperature; remove the floa...

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Abstract

The invention discloses a functional peptide with the cosmetic efficacy and a preparation method and an application thereof. The functional peptide is a composite product of an elastin peptide and a collagen peptide, and the preparation method of the functional peptide with the cosmetic efficacy includes the following steps: soaking elastin raw materials with a NaCl solution to remove oil, and soaking collagen raw materials with a NaOH solution to remove oil; then conducting centrifugation or mincing to obtain an elastin crude extract and a collagen crude extract, and then mixing the elastin crude extract with the collagen crude extract, conducting enzymatic hydrolyzing with protease, and then spray drying the obtained enzymatic hydrolysate to obtain the functional peptide with the cosmetic efficacy. According to the preparation method, the elastin and collagen are simultaneously treated by a biological enzymolysis technology, while the elastin peptide and the collagen peptide with the cosmetic efficacy are released, the elastin peptide and the collagen peptide are better mixed during the enzymatic hydrolysis process. The composite product of the elastin peptide and the collagen peptide, prepared by the method, has the obvious efficacy of moisturizing and resisting wrinkle, and can significantly improve the moisture content and the collagen content in the skin.

Description

technical field [0001] The invention belongs to the field of deep processing of protein raw materials, and in particular relates to a functional peptide (composite product of elastin peptide and collagen peptide) with cosmetic effect, its preparation method and application. Background technique [0002] Elastin and collagen are important structural proteins in the skin, which are composed of abundant fibrils. Both elastin and collagen have multiple repeating sequences and abundant polar amino acids (accounting for more than 90% of the total amino acids). Collagen contains specific amino acids - hydroxyproline and hydroxylysine, which is a triple helix structure formed by two α chains and one β chain cross-linked; while elastin contains a special cross-linked structure - chain Desmosin and isodesmosin, the soluble precursor protein of elastin, tropoelastin, form a compact protein structure through cross-linking of desmosin and isodesmosin. Both proteins are water-insoluble ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07K14/78C12P21/06A23J3/34A23J3/06A23J3/04C07K2/00A61K8/64A61K8/65A61Q19/00A61Q19/08
CPCA23J3/341A23J3/342A61K8/64A61K8/65A61Q19/00A61Q19/08C07K2/00C07K14/78C12P21/06
Inventor 赵谋明苏国万刘洋
Owner 广州精准健康生物科技有限公司
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