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Autogenous cartilage and titanium framework combined material for nose plastic filling and preparation method of such material

An autogenous bone and nose technology, applied in prostheses, nose implants, medical science, etc., can solve the problems of complex production process, easy displacement and wear, and achieve the effect of preventing pain and movement

Pending Publication Date: 2017-03-08
大连裕辰科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention provides a material for rhinoplasty and filling autologous bone combined with titanium bracket and its preparation method to solve the problems in the prior art that the manufacturing process is relatively complicated and prone to displacement and wear

Method used

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  • Autogenous cartilage and titanium framework combined material for nose plastic filling and preparation method of such material
  • Autogenous cartilage and titanium framework combined material for nose plastic filling and preparation method of such material
  • Autogenous cartilage and titanium framework combined material for nose plastic filling and preparation method of such material

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preparation example Construction

[0044] Reference image 3 As shown, the present invention also proposes a method for preparing a material for rhinoplasty filled with autogenous bone joint titanium stent, including the following steps:

[0045] A) The base body is made, the nasal bone base is made of titanium alloy material;

[0046] B) Take bone and obtain autologous cartilage in a sterile environment;

[0047] C) Treatment: the obtained autologous cartilage is sequentially processed for degreasing, decalcification, deproteinization and sterilization;

[0048] D) Cultivation, assembling the processed autologous cartilage in step C on the nasal bone matrix, and culturing for 24 hours,

[0049] E) sculpting, sculpting the nasal bone matrix into a desired shape after the cultivation in step D).

[0050] The specific processing procedure in step C of the present invention includes:

[0051] (1) Immerse the autologous cartilage in a mixture of chloroform and methanol for 6-24 hours; wherein: the volume ratio of chloroform an...

Embodiment 1

[0057] 1. The nasal bone base is made of titanium alloy material, and there are many hollow holes on the nasal bone base;

[0058] 2. Obtain autologous rib cartilage in a sterile environment; preferably take the eleventh or twelfth rib, clean it with distilled water and soak it;

[0059] 3. Immerse the autologous cartilage in a mixed liquid of chloroform and methanol for 24 hours for degreasing; wherein: the volume ratio of chloroform and methanol in the mixed liquid of chloroform and methanol is 1:1, and wash with distilled water after taking it out;

[0060] 4. Immerse the degreased autologous cartilage in a hydrochloric acid solution with a concentration of 0.5 mol / L and continue to stir for 12 hours for decalcification, and then wash it with distilled water after taking it out;

[0061] 5. Immerse the decalcified autologous cartilage in a mixed solution of TritonX-100 and ammonia for 72 hours to deproteinize; wherein the volume percentage of TritonX-100 in the mixed solution of Tri...

Embodiment 2

[0066] 1. The nasal bone base is made of titanium alloy material, and there are many hollow holes on the nasal bone base;

[0067] 2. Obtain autologous ear cartilage in a sterile environment; clean and soak with distilled water;

[0068] 3. Immerse the autologous cartilage in a mixed liquid of chloroform and methanol for 24 hours for degreasing; wherein: the volume ratio of chloroform and methanol in the mixed liquid of chloroform and methanol is 1:1, and wash with distilled water after taking it out;

[0069] 4. Immerse the defatted autologous cartilage in a hydrochloric acid solution with a concentration of 0.6 mol / L, and continue to stir for 12 hours for decalcification, and then wash it with distilled water;

[0070] 5. Immerse the decalcified autologous cartilage in a mixed solution of TritonX-100 and ammonia for 72 hours to deproteinize; wherein the volume percentage of TritonX-100 in the mixed solution of TritonX-100 and ammonia is 1%, The mass percentage of ammonia is 0.3%, an...

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Abstract

The invention relates to an autogenous cartilage and titanium framework combined material for nose plastic filling and a preparation method of such material. The autogenous cartilage and titanium framework combined material comprises a nasal bone matrix prepared from a titanium alloy, and the nasal bone matrix comprises a nasal tip, a nasal columella and a nose bridge, wherein the nose bridge is connected with the nasal columella through the nose tip. A narrowed transition segment is arranged between the nose bridge and the nose tip and is narrower than the nose bridge, the lower portion of the nose bridge is composed of two intersectional V-shaped nose bridge segments, a nose bone of a human body is positioned between the two nose bridge segments, and the nasal bone matrix is provided with a hollow-out body filled with autogenous cartilages. The autogenous cartilage and titanium framework combined material has the advantages that through the design of the nose bridge segments, a prosthesis can be in close contact with the nose bone, and displacement or wear is avoided; body fluid can flow into pores in the nose bridge to promote stable integration of a nose and the nose prosthesis, and accordingly the nose prosthesis can be protected from moving, shedding and ulcerating, and postoperative pain of a patient is prevented. The preparation method is applicable to treatment of autogenous cartilages and alloplastic bones.

Description

Technical field [0001] The invention relates to the technical field of plastic surgery, in particular to a material used for nasal plastic filling and autogenous bone joint titanium stent and a preparation method thereof. Background technique [0002] Rhinoplasty (plastic) surgery involves implanting appropriate materials to change the height and shape of the nose to make it coordinate with other parts of the face. It is the most common surgery in the field of plastic surgery. [0003] Medically, there are many kinds of rhinoplasty materials, such as medical silicone rubber, autologous cartilage, allogeneic cartilage, animal tendons or ligaments, bulging (polytetrafluoroethylene), hyaluronic acid, etc. There are also many preparation methods for nasal bridge prostheses. Among them, autogenous cartilage will not be rejected due to its own source and will not be sensitized. However, it is difficult to shape and increase patient suffering during the manufacturing process. It uses all...

Claims

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Application Information

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IPC IPC(8): A61F2/18
CPCA61F2/186A61F2240/001
Inventor 于浩
Owner 大连裕辰科技发展有限公司
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