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Method for serially extracting two effective ingredients from Periplaneta americana

A technology of Periplaneta americana and active ingredients, applied in the field of medicine, can solve the problems of economic waste, inability to fully utilize Periplaneta americana, high cost, etc., and achieve the effect of improving the cure rate

Inactive Publication Date: 2017-01-04
KUNMING SINOWAY NATURAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The present invention provides a preparation method for serially extracting two active ingredients from Periplaneta americana, which solves the problems that existing extraction methods cannot make full use of the original medicinal materials of Periplaneta americana, resulting in economic waste and high cost.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] A method for serially extracting two active ingredients from Periplaneta americana, comprising the following steps:

[0045] (1) Preparation of Periplaneta americana liquid extract:

[0046] A) pulverization: the dry Periplaneta americana body is pulverized, and crosses a 24-mesh sieve to obtain the Periplaneta americana meal;

[0047] B) Soaking: Soak the Periplaneta americana coarse powder obtained in step A) with ethanol with a mass concentration of 95%, so that the ethanol liquid level is higher than the Periplaneta americana coarse powder by 5-10 cm and airtightly preserved to prepare the coarse powder mixture;

[0048] C) Extraction: The coarse powder mixture obtained in step B) is subjected to reflux extraction for 3 times at a temperature of 75 to 80°C. When the coarse powder mixture is extracted for the first time, increase the weight of the coarse powder to 6 times the mass concentration of 92%. The ethanol of 4 times of mass concentration of thick powder wei...

Embodiment 2

[0063] A method for serially extracting two active ingredients from Periplaneta americana, comprising the following steps:

[0064] (1) Preparation of Periplaneta americana liquid extract:

[0065] A) pulverization: the dry Periplaneta americana body is pulverized, and crosses a 24-mesh sieve to obtain the Periplaneta americana meal;

[0066] B) Soaking: Soak the Periplaneta americana coarse powder obtained in step A) with ethanol with a mass concentration of 90%, so that the ethanol liquid level is higher than the Periplaneta americana coarse powder by 5-10 cm and airtightly preserved to prepare the coarse powder mixture;

[0067] C) Extraction: The coarse powder mixture obtained in step B) is subjected to reflux extraction for 4 times at a temperature of 75 to 80°C. When the coarse powder mixture is extracted for the first time, increase the weight of the coarse powder to 5 times the mass concentration of 90%. The ethanol of 3 times the weight of the coarse powder was extra...

Embodiment 3

[0082] A method for serially extracting two active ingredients from Periplaneta americana, comprising the following steps:

[0083] (1) Preparation of Periplaneta americana liquid extract:

[0084] A) pulverization: the dry Periplaneta americana body is pulverized, and crosses a 24-mesh sieve to obtain the Periplaneta americana meal;

[0085] B) Soaking: Soak the Periplaneta americana coarse powder obtained in step A) with ethanol with a mass concentration of 92%, so that the ethanol liquid level is higher than the Periplaneta americana coarse powder by 5-10 cm and airtightly preserved to obtain a coarse powder mixture;

[0086] C) Extraction: The coarse powder mixture obtained in step B) is subjected to reflux extraction for 5 times at a temperature of 75 to 80°C. When the coarse powder mixture is extracted for the first time, increase the weight of the coarse powder to 6 times the mass concentration of 90%. The ethanol of 4 times the weight of coarse powder was extracted fo...

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PUM

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Abstract

The invention relates to a method for serially extracting two effective ingredients from Periplaneta Americana. The method includes the steps of (1), preparing Periplaneta americana fluid extract, to be more specific, subjecting Periplaneta americana bodies to crushing, ethanol soaking, ethanol reflux extraction, primary concentration, degreasing and secondary concentration to obtain extract with the proportion being 1.05-1.15, namely the Periplaneta americana fluid extract; (2), preparing the first effective ingredient; (3), preparing the second effective ingredient. The method has the advantages that the raw Periplaneta americana is fully utilized, the two effective ingredients are serially extracted from Periplaneta americana, cost is greatly reduced, high operability is achieved, and the method is economical and reasonable.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a method for serially extracting two active ingredients from Periplaneta americana. Background technique [0002] Periplaneta americana is an insect of the genus Periplaneta in the family Blattadiae, commonly known as the cockroach, which is the largest insect in the family Blatella, native to South America. Periplaneta americana is a traditional Chinese medicinal material that was first recorded in "Shen Nong's Materia Medica". Treatment of infantile malnutrition, boils, carbuncle, throat moth, unknown swelling poison, syphilis, poisonous snake, centipede pine bite and other diseases. [0003] With the continuous development of modern science, the research on the chemical composition and pharmacological effects of Periplaneta americana has become more and more in-depth. According to literature reports, Periplaneta americana contains proteins, peptides, amino acids, chitin, mu...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61P35/00A61P1/16A61P31/20
CPCA61K35/63
Inventor 郝振平徐溧
Owner KUNMING SINOWAY NATURAL PHARMA
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