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A kind of preparation method of bletilla striata base dressing

A bletilla striata-based and bletilla striata polysaccharide technology, which is applied in pharmaceutical formulations, bandages, drug delivery, etc., can solve the problems of easy splitting, blood easily breaking through the fibrous membrane, and low degree of mutual intersection, so as to improve mechanical properties and expand application fields Effect

Active Publication Date: 2019-04-19
质每堂(武汉)健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the interior of the fibrous membrane is a simple parallel laminated structure, and the degree of crossing between the parallel laminated pages is low, which is prone to splitting. During use, the blood is easy to break through the fibrous membrane, which directly reduces the hemostatic effect of the fibrous membrane.

Method used

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Examples

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Effect test

preparation example Construction

[0019] A preparation method of bletilla striata-based dressing, wherein the extraction of bletilla striata polysaccharide and the preparation of bletilla striata polysaccharide fiber can refer to Chinese patent publication number CN102961776A, the date of publication is March 13, 2013, and the title of the invention is: a preparation of bletilla striata hemostatic gauze method. Described preparation method carries out as follows:

[0020] Described preparation method carries out as follows:

[0021] a Bletilla striata polysaccharide extraction

[0022] Soak dried bletilla striata stems and distilled water at a mass ratio of 1:5 to 1:10, soaking time is 0.5h to 2h, soaking temperature is 40-80°C, filters through gauze, and collects the polysaccharide filtrate of bletilla striata.

[0023] After extracting the Bletilla striata polysaccharide filtrate, continue the above soaking and filtering process for 4 to 10 times, combine the Bletilla striata polysaccharide filtrate collec...

Embodiment 1

[0034] a Bletilla striata polysaccharide extraction

[0035] Soak the dried stems of Bletilla striata with distilled water at a mass ratio of 1:5 for 0.5 h at a temperature of 40°C, filter through gauze, and collect the polysaccharide filtrate of Bletilla striata.

[0036] After extracting the Bletilla striata polysaccharide filtrate, continue the above soaking and filtering process for 4 times, combine the Bletilla striata polysaccharide filtrate collected in stages, and place it in a blast drying oven at 50°C to concentrate to obtain concentrated Bletilla striata polysaccharides with a mass concentration of 1.5%. liquid.

[0037] Add absolute ethanol to the bletilla striata polysaccharide concentrate obtained above and stir, ethanol precipitation, filter to obtain a precipitate, and wash the precipitate obtained by filtration with absolute ethanol, wherein, the volume of absolute ethanol added for alcohol precipitation is the volume of bletilla striata polysaccharide concent...

Embodiment 2

[0046] a. Extraction of Bletilla striata polysaccharide

[0047] Soak the dried bletilla striata stems and distilled water at a mass ratio of 1:6 for 1 hour at a soaking temperature of 55°C, filter through gauze, and collect the bletilla striata polysaccharide filtrate.

[0048] After extracting the bletilla striata polysaccharide filtrate, continue the above soaking and filtering process for 6 times, combine the bletilla striata polysaccharide filtrate collected in stages, and place it in a blast drying oven at 65°C to concentrate to obtain concentrated bletilla striata polysaccharides with a mass concentration of 2.5%. liquid.

[0049] Add absolute ethanol to the bletilla striata polysaccharide concentrate obtained above and stir, ethanol precipitation, filter to obtain a precipitate, and wash the precipitate obtained by filtration with absolute ethanol, wherein, the volume of absolute ethanol added for alcohol precipitation is the volume of bletilla striata polysaccharide c...

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Abstract

The invention belongs to the technical field of medical dressings and relates to a Rhizoma bletillae based dressing preparation method. The preparation method includes: dissolving Rhizoma bletillae polysaccharide powder extracted from natural bletilla tubers into water to obtain a Rhizoma bletillae polysaccharide solution; taking absolute ethyl alcohol as a coagulating bath to prepare fibers, and constructing the fibers as a reinforcement layer; according to a directional ice crystal induced growth technology, realizing freeze forming of the Rhizoma bletillae polysaccharide solution to along a direction perpendicular to filaments, and subjecting the Rhizoma bletillae polysaccharide solution and the fibers to freeze drying in a vacuum low-temperature environment after curing is finished, so that the Rhizoma bletillae based dressing is obtained. The Rhizoma bletillae based dressing preparation method is simple in process, low in cost and free of chemical reagents and harmful substances. Since the filaments and laminates in the Rhizoma bletillae based dressing prepared according to the method form a vertically intersected array structure, the Rhizoma bletillae based dressing has excellent mechanical properties and is applicable to the fields of functional dressings and tissue engineering.

Description

technical field [0001] The invention relates to a preparation method of a bletilla striata-based dressing, which belongs to the technical field of medical dressings. Background technique [0002] Bletilla striata is a species of Bletilla striata in the family Orchidaceae. Its pseudobulb has a good hemostatic function, and its main components contain mannose, starch, and volatile oil. In medicine, it has the effects of astringent and hemostasis, detumescence and muscle growth, and tissue protection. It is a good natural bioengineering material and can be used as a medical dressing for pharmaceutical preparations. At present, the use forms of bletilla striata mainly include bletilla striata powder and bletilla striata glue. [0003] The Chinese patent publication number is CN101249274A, and the date of disclosure is August 27, 2008. The title of the invention is: the preparation method of Bletilla striata polysaccharide hydrogel that promotes wound healing. Composed of ionic...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L15/40A61L15/28A61L15/44
CPCA61L15/28A61L15/40A61L15/44A61L2300/232A61L2300/418A61L2400/04C08L5/00
Inventor 庄燕张骞杨红军徐卫林王娜卜怿明
Owner 质每堂(武汉)健康科技有限公司
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