Traditional Chinese medicinal preparation for treating orthopedic diseases, and preparation method and application thereof

A technology for traditional Chinese medicine preparations and orthopedic diseases, applied in the field of medicine, can solve the problems of increasing the economic burden of patients, unable to achieve radical cure, adverse physical effects, etc., and achieve the effects of no toxic side effects, wide application range and low production cost.

Inactive Publication Date: 2016-10-26
THE SECOND HOSPITAL AFFILIATED TO WENZHOU MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Especially femoral head necrosis and hyperosteogeny, not only last for a long time, but also difficult to cure
At present, most of the pain medicines for the above-mentioned diseases are western medicines, such as: Fenbid, Pain Relief Tablets, etc., the clinical effect is better, but the side effects are relatively large, they cannot play a radical role, relapse after drug withdrawal, and some medicines are relatively expensive High, long-term use increases the economic burden of patients, and also has adverse effects on their bodies

Method used

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  • Traditional Chinese medicinal preparation for treating orthopedic diseases, and preparation method and application thereof
  • Traditional Chinese medicinal preparation for treating orthopedic diseases, and preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0025] In the embodiment of the present invention, a traditional Chinese medicine preparation for the treatment of orthopedic diseases is composed of the following raw materials in parts by weight: 16 parts of calyx calyx, 20 parts of banana leaves, 1 part of catechu, 11 parts of red nan root, and 8 parts of bamboo fungus share.

[0026] Grind the root of Chinan, pass through a 100-mesh sieve, use ethanol 5 times its mass as an entrainer, and use CO 2 Supercritical extraction to produce red Nan root CO 2 Supercritical extract; specific parameters are: extraction kettle temperature 75°C, extraction pressure 10MPa, flow rate 8L / h, extraction time 4h; first separation kettle: temperature 58℃, separation pressure 5MPa; second separation kettle: temperature 45℃, Separation pressure 2MPa; 2 The supercritical extract is adsorbed by macroporous resin, pre-washed with 10% ethanol, and then eluted with 75% ethanol at a flow rate of 7L / h. Pulverize catechu and bamboo fungus, pass thro...

Embodiment 2

[0028] In the embodiment of the present invention, a traditional Chinese medicine preparation for the treatment of orthopedic diseases is composed of the following raw materials in parts by weight: 24 parts of calyx calyx, 28 parts of banana leaves, 5 parts of catechu, 20 parts of red nan root, and 16 parts of bamboo fungus share.

[0029] Grind the root of Chinan, pass through a 100-mesh sieve, use ethanol 5 times its mass as an entrainer, and use CO 2 Supercritical extraction to produce red Nan root CO 2 Supercritical extract; specific parameters are: extraction kettle temperature 75°C, extraction pressure 10MPa, flow rate 9L / h, extraction time 4.5h; first separation kettle: temperature 60℃, separation pressure 5MPa; second separation kettle: temperature 45℃ , separation pressure 2MPa; 2 The supercritical extract is adsorbed by macroporous resin, pre-washed with 20% ethanol, and then eluted with 75% ethanol at a flow rate of 7L / h. Pulverize catechu and bamboo fungus, pass...

Embodiment 3

[0031] In the embodiment of the present invention, a traditional Chinese medicine preparation for the treatment of orthopedic diseases is composed of the following raw materials in parts by weight: 18 parts of calyx calyx, 22 parts of banana leaves, 2 parts of catechu, 13 parts of red nan root, and 10 parts of bamboo fungus share.

[0032] Grind the root of Chinan, pass through a 100-mesh sieve, use ethanol 5 times its mass as an entrainer, and use CO 2 Supercritical extraction to produce red Nan root CO 2 Supercritical extract; specific parameters are: extraction kettle temperature 75°C, extraction pressure 10MPa, flow rate 8.5L / h, extraction time 4.2h; first separation kettle: temperature 59℃, separation pressure 5MPa; second separation kettle: temperature 45 ℃, separation pressure 2MPa; 2 The supercritical extract was adsorbed by macroporous resin, pre-washed with 15% ethanol, and then eluted with 75% ethanol at a flow rate of 7L / h. Pulverize catechu and bamboo fungus, p...

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Abstract

The invention discloses a traditional Chinese medicinal preparation for treating orthopedic diseases, and a preparation method and an application thereof. The traditional Chinese medicinal preparation comprises, by weight, 16-24 parts of Herb of Dwarf Denseflower Elsholtzia, 20-28 parts of Sago Leaf, 1-5 parts of catechu, 11-20 parts of root of Syzygium buxifolium Hook. et Arn. and 8-16 parts of Dictyophora indusiata. The preparation method comprises the following steps: crushing the root of Syzygium buxifolium Hook. et Arn., carrying out CO2 supercritical extraction, adsorbing the obtained extract with macro-porous adsorption resin, pre-eluting the extract, and eluting the extract to obtain a Syzygium buxifolium Hook. et Arn. root medicine liquid; crushing catechu and Dictyophora indusiata, and carrying out high temperature treatment to obtain mixed powder; adding 50% ethanol to Dwarf Denseflower Elsholtzia and Sago Leaf to immerse Dwarf Denseflower Elsholtzia and Sago Leaf, heating the immersed materials to boil the immersed materials, filtering the obtained solution, and taking the obtained filtrate; and mixing the filtrate with the mixed powder and the Syzygium buxifolium Hook. et Arn. root medicine liquid, and carrying out heat treatment to obtain the traditional Chinese medicinal preparation. The traditional Chinese medicinal preparation has the efficacy of invigorating blood circulation and strengthening bones, warming channels and expelling cold, and relaxing veins and relieving pains, can be used to treat hyperosteogeny, femur head necrosis, traumatic injury and various orthopedic diseases and has the characteristics of fast effect, high cure rate, no recurrence after cure, no toxic or side effects, low production cost, and convenience for industrial production.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine preparation for treating orthopedic diseases, a preparation method and application thereof. Background technique [0002] With the aging of the population and changes in the way people live and work, orthopedic diseases are on the rise. Clinically, orthopedic diseases generally include cervical spondylosis, hyperosteogeny, arthritis, femoral head necrosis, bruises, etc. Its clinical symptoms are mainly manifested as pain, redness and swelling, stiffness, and movement disorder in the affected area. The course of the disease is very long, which seriously affects the normal life of the patient. Especially femoral head necrosis and hyperosteogeny, not only duration is long, also is difficult to cure. At present, most of the pain medicines for the above-mentioned diseases are western medicines, such as: Fenbid, Pain Relief Tablets, etc., the clinical ...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61P19/02A61P19/08A61P29/00
CPCA61K36/53A61K36/07A61K36/13A61K36/48A61K36/61A61K2236/333A61K2236/37A61K2236/55A61K2300/00
Inventor 吴爱悯黄义星林仲可池永龙金海明陈春慧陈坚倪文飞王向阳
Owner THE SECOND HOSPITAL AFFILIATED TO WENZHOU MEDICAL COLLEGE
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