A method and device for evaluating bone collagen content based on resonance state

Abstract

The invention discloses a method and device for evaluating bone collagen content based on a resonance state, which includes a laser, a laser controller, a display module, an ultrasonic transducer, a preamplifier, a lock-in amplifier and a coupling agent. The coupling Pasted on human skin, the device reported in the present invention can realize the detection of bone collagen content, solve the problem that in the existing evaluation of bone quality, only rely on the single evaluation value of bone density, and at the same time realize the control of collagen content on the bone surface. influence of the signal. The invention has the obvious advantages of no trauma, no radiation, low detection cost, accurate evaluation and the like.

Description

technical field [0001] The invention relates to a measuring device for medical detection of bone quality level, in particular to a method and device for evaluating bone collagen content based on a resonance state. Background technique [0002] Dual-energy X-ray absorptiometry (DXA), as an important standard for detecting bone quality, was widely used clinically in the 1990s, but in a large number of clinical practices, people have safety and accuracy for DXA detection of bone health. doubts on two fronts. Especially for infants, convalescence and special populations, it is not suitable to use DXA for dynamic monitoring. Studies have shown that the use of high-dose γ-rays in the process of bone repair can cause 62% of the α-chains in collagen to break and lose their recovery function. [0003] Early osteoporosis is not only manifested in the decrease of bone density, but also the loss of collagen and the trauma of microstructure are also the characteristics of early osteopor...

AI Technical Summary

Problems solved by technology

[0002] Dual-energy X-ray absorptiometry (DXA), as an important standard for detecting bone quality, was widely used clinically in the 1990s, but in a large number of clinical practices, people have safety and accuracy for DXA detection of bone health. Doubt on two fronts

Especially for infants, convalescence and special populations, it is not suitable to use DXA for dynamic monitoring. Studies have shown that the use of high-dose γ-rays in the process of bone repair can cause 62% of the α-chains in collagen to break and lose their recovery function.

[0003] Early osteoporosis is not only manifested in the decrease of bone density, but also the loss of collagen and the trauma of microstructure are also the characteristics of early osteoporosis, but bone collagen not only exists in the bone tissue, but also widely exists on the bone surface And skin tissue, the photoacoustic / ultrasonic signal entering the bone tissue will be affected by the collagen in the above tissue. In the non-destructive testing of bone tissue, there is still no reasonable solution to this problem.

At present, there is no method found in public reports that can effectively solve the collagen content of bone, especially the collagen content in cancellous bone

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