Microparticle Manufacturing Method

Abstract

Provided is a method for producing fine particles, comprising: a dissolving step of dissolving at least one kind of fine particle raw materials in a solvent using a stirrer having a rotating stirring blade to obtain a fine particle raw material solution; At least one of the precipitated solvents and the fine particle raw material solution are introduced between at least two processing surfaces that are oppositely arranged, accessible and / or separate, and at least one of them rotates relative to the other. This is a precipitation step in which fine particles are precipitated by mixing in the thin film fluid formed between the treatment surfaces. In the above-mentioned dissolving step, the stirring energy specified by the stirring time conditions using the stirrer, the peripheral speed conditions of the stirring blades, and the temperature conditions of the fine particle raw material solution is increased or decreased by changing at least one of the above conditions. , by increasing or decreasing the stirring energy, the crystallinity and crystal form of the particles obtained in the precipitation step are controlled.

Description

technical field [0001] The present invention relates to a method for producing microparticles. Background technique [0002] Microparticles such as metals, oxides, pharmaceuticals, foods, cosmetics, and other living body ingestible substances, and pigments are required in a wide range of fields in the industry. [0003] The production method of microparticles generally uses a flask, a beaker, a tank, etc. as described in Patent Document 1 to perform reactions such as poor solvent method, crystallization, oxidation, and reduction. It is difficult to uniformly maintain the concentration and temperature in the container, so the particle size distribution of the obtained particles tends to widen. In addition, in the case of producing fine particles such as alloys and composite oxides containing two or more elements, it is difficult to obtain them in a homogeneous manner. Element ratios make particles. In addition, a method for producing microparticles using a microreactor as d...

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Problems solved by technology

[0005] However, even in the case of using the method described in Patent Document 3, it may be difficult to stably produce fine particles. When producing fine particles containing two or more molecules and elements, the local element ratio may vary. Even, it may be difficult to produce uniform and homogeneous particles

[0006] Furthermore, even if the method described in Patent Document 4 is used in combination, if the operating conditions of the device such as the formulation of the fluid to be processed, the liquid delivery amount, the temperature, and the rotational speed of the processing surface are simply changed, the resulting However, it is difficult to realize the desired crystallinity, crystal form or composition ratio of a specific crystal form, and no specific method for freely controlling the properties / characteristics of the particles such as crystallinity, crystal form or composition ratio of a specific crystal form has been disclosed, room for improvement

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