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Bacteriostatic medical functional dressing

A technology of functions and raw materials, applied in the field of antibacterial medical functional dressings, can solve the problems that need to be further improved, do not have antibacterial effect, etc., and achieve good clinical application prospects, shorten healing time, and excellent mechanical properties

Inactive Publication Date: 2016-08-31
林春梅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the application of hydrogel dressings also has certain limitations. It is not suitable for wounds with a lot of exudate, and the surrounding skin is fragile or infected wounds. In addition, hydrogel dressings themselves do not have antibacterial effect, and their treatment The effect of wound healing also needs to be further improved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A bacteriostatic medical functional dressing prepared from the following parts by weight: 90 parts of β-chitosan, 10 parts of potassium alginate, 20 parts of xylan, 12 parts of γ-polyglutamic acid, and aldehyde 20 parts of hyaluronic acid, 10 parts of gum arabic, 0.8 parts of cell growth factor, 6-20 parts of phytosterols, 5 parts of ginkgo flavone, 30 parts of 2mol / L peony root extract, 1.2mol / L of Dalbergia odorifera extract 40-60 Parts, 35 parts of 1mol / L cattail yellow extract, 8 parts of sorbitol, 6 parts of vitamin K3, 15 parts of 1,4-butanediol diglycidyl ether, 2 parts of sodium sulfite, 3 parts of chlorhexidine acetate, polyvinylpyrrolidone 3 parts, 200 parts of distilled water.

[0024] The cell growth factors include transforming growth factor, 12ng / ml interleukin 10 and 24ng / ml platelet-derived factor at concentrations of 165ng / ml, respectively.

[0025] The peony root extract, Dalbergia odorifera extract, and Typhae typhae extract are respectively sterilized wa...

Embodiment 2

[0033] A bacteriostatic medical functional dressing prepared from the following parts by weight of raw materials: 105 parts of β-chitosan, 20 parts of potassium alginate, 30 parts of xylan, 15 parts of γ-polyglutamic acid, and aldehyde 30 parts of hyaluronic acid, 14 parts of gum arabic, 3.4 parts of cell growth factor, 13 parts of phytosterols, 10 parts of ginkgo flavonoids, 50 parts of 2mol / L peony root extract, 50 parts of 1.2mol / L dalbergia extract, 1mol / L 51 parts of L. Typhae extract, 11 parts of sorbitol, 8 parts of vitamin K3, 22 parts of 1,4-butanediol diglycidyl ether, 5 parts of sodium sulfite, 6 parts of chlorhexidine acetate, 7 parts of polyvinylpyrrolidone, distilled water 250 copies.

[0034] The cell growth factors include transforming growth factor, 12ng / ml interleukin 10 and 24ng / ml platelet-derived factor at concentrations of 165ng / ml, respectively.

[0035] The peony root extract, Dalbergia odorifera extract, and Typhae typhae extract are respectively sterilize...

Embodiment 3

[0043] A bacteriostatic medical functional dressing prepared from the following parts by weight of raw materials: 120 parts by weight of β-chitosan, 30 parts of potassium alginate, 40 parts of xylan, 17 parts of γ-polyglutamic acid, and hydroformylation 40 parts of hyaluronic acid, 18 parts of gum arabic, 6 parts of cell growth factors, 20 parts of phytosterols, 15 parts of ginkgo flavonoids, 70 parts of 2mol / L peony root extract, 60 parts of 1.2mol / L dalbergia extract, 1mol / L 68 parts of L. Typhae extract, 14 parts of sorbitol, 10 parts of vitamin K3, 29 parts of 1,4-butanediol diglycidyl ether, 8 parts of sodium sulfite, 9 parts of chlorhexidine acetate, 11 parts of polyvinylpyrrolidone, distilled water 300 copies.

[0044] The cell growth factors include transforming growth factor, 12ng / ml interleukin 10 and 24ng / ml platelet-derived factor at concentrations of 165ng / ml, respectively.

[0045] The peony root extract, Dalbergia odorifera extract, and Typhae typhae extract are res...

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PUM

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Abstract

The invention discloses a bacteriostatic medical functional dressing. The bacteriostatic medical functional dressing is prepared from beta-chitosan, potassium alginate, xylan, gamma-polyglutamic acid, hydroformylated hyaluronic acid, Arabic gum, cell growth factors, phytosterol, ginkgetin, 2mol / L peony root extract, 1.2mol / L lignum dalbergiae odoriferae extract, 1mol / L pollen typhae extract, sorbitol, vitamin K3, 1,4-butanediol diglycidyl ether, sodium sulfite, chlorhexidine acetate, polyvinylpyrrolidone and distilled water. The tensile strength and elongation at break of the prepared medical functional dressing are both at a high level, the mechanical performance is excellent, the bacteriostasis rate is higher than 98.5%, and the healing time is as short as 5-8 days. The prepared medical functional dressing is low in toxicity and good in mechanical performance, the healing time is shortened, the bacteriostasis rate is achieved, and good clinical application prospects are achieved.

Description

Technical field [0001] The invention belongs to the technical field of medical materials, and specifically relates to a bacteriostatic medical functional dressing. Background technique [0002] In recent years, injuries caused by trauma, abrasions, burns, surgical incisions, ulcers, etc. are not uncommon. After the skin is injured, its immunity decreases and it is easily infected by viruses. For this reason, traditional methods similar to gauze are usually used. Medical dressings isolate the damaged skin. However, traditional medical dressings are easy to harden and will cause secondary damage when replaced again, which is not conducive to wound healing. In order to solve this problem, various new medical functional dressings have appeared. The new medical functional dressing combines the knowledge of biology, physiology, surgery, nursing and nutrition. Its main feature is to prevent the formation of scabs, does not adhere to the newly formed granulation tissue, and is painless ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/44A61L15/42A61L15/40A61L15/28A61L15/26A61L15/24A61L15/20
CPCA61L15/44A61L15/20A61L15/24A61L15/26A61L15/28A61L15/40A61L15/42A61L2300/30A61L2300/404A61L2300/414C08L39/06C08L77/04C08L5/08C08L5/04C08L5/00
Inventor 林春梅
Owner 林春梅
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