A constant temperature total internal reflection microfluidic chip detection all-in-one machine

Abstract

The invention discloses a constant-temperature total-internal-reflection microfluidic-chip detection all-in-one machine. The all-in-one machine consists of a host box body and a processing display and is characterized in that the interior of the host box body is divided into box chambers of two layers, i.e., a lower-layer box chamber and an upper-layer box chamber, the lower-layer box chamber is provided with an inverted fluorescent microscope, and a total-internal-reflection light source and a receiver are mounted in the upper-layer box chamber. A heating chamber is formed in a box body wall of the inner side of the upper-layer box chamber. The processing display is in line connection with the inverted fluorescent microscope, the total-internal-reflection light source and the receiver in the host box body. The all-in-one machine has the advantages that detection can be carried out by using total internal reflection and can also be carried out by using the inverted fluorescent microscope so as to achieve multiple purposes and meet the requirements that different factors are simultaneously detected by one machine. The temperature and humidity of a detected area can be uniform and constant.

Description

technical field [0001] The invention relates to an in vitro diagnostic all-in-one machine, more specifically, a constant-temperature total internal reflection microfluidic chip detection all-in-one machine belonging to the field of in vitro diagnosis of medical equipment. Background technique [0002] In vitro diagnosis refers to the diagnosis of blood, body fluid, and tissue samples taken out of the human body for testing. At present, more than 80% of clinical disease diagnoses rely on IVD, which is known as the "eyes" of doctors. IVD plays an increasingly important role in modern society, especially pre-bed instant diagnosis plays an extremely important role in the whole process of disease prevention, diagnosis, monitoring and guiding treatment, and is indispensable for modern disease and health management Tool of. Due to the rapid development of microfluidic chips, the bottleneck hindering the development of microfluidic technology today is still the problems in manufact...

AI Technical Summary

Problems solved by technology

Due to the rapid development of microfluidic chips, the bottleneck hindering the development of microfluidic technology today is still the problems in manufacturing, processing and application that limited its development in the early days.

Total internal reflection optical detection technology is an optical detection technology that is compatible with the integration of microfluidic chips. However, when using these two technologies to detect living cells, there is a lack of a constant temperature all-in-one machine that meets the requirements of live cell detection.

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