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Method for preparing throat lozenge

A throat moistening and water content technology, applied in the field of lozenges, can solve the problems of easy deactivation of active ingredients, solvent residue process, unsuitable for long-term use, etc., and achieve the effects of improving production efficiency, saving manpower, and uniform internal density

Inactive Publication Date: 2016-07-13
马占平 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many medicines on the market for clearing and moisturizing the throat. The main effects are to clear away heat and relieve fire, reduce swelling and relieve pain.
Some Chinese medicinal materials will be introduced in the process of making lozenge lozenges. When extracting the active ingredients in Chinese medicinal materials, they are mainly obtained after treatment by leaching, ultrasonic extraction and single enzymatic hydrolysis. low, active ingredients are easily deactivated, solvent residues and complex processes, etc.

Method used

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  • Method for preparing throat lozenge

Examples

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Effect test

Embodiment 1

[0053] A preparation method of throat lozenges, comprising the following steps:

[0054] Step 1. Put 40 parts by weight of Golden Camellia, 5 parts by weight of Panda Dahai, 7 parts by weight of mint leaves, 8 parts by weight of honeysuckle and 5 parts by weight of licorice at a temperature of 50 ° C and a vacuum of -0.07 MPa. Vacuum-dry until the water content is less than 10%, and then pulverize to 30 mesh with a pulverizer to obtain camellia japonica powder, fat sea powder, peppermint powder, honeysuckle powder and licorice powder, and set aside;

[0055] Step 2: Mix the camellia powder, the fat sea powder, the peppermint powder, the honeysuckle powder and the licorice powder, put them in 100 parts by weight of water, and then add 0.01 parts by weight of cellulase and 0.008 parts by weight of pectinase, adjusted the pH value to 5 with citric acid, stirred evenly, and enzymolyzed at 45° C. for 1.5 hours to obtain an enzymolyzed solution for use; plant cell walls can be destr...

Embodiment 2

[0092] A preparation method of throat lozenges, comprising the following steps:

[0093] Step 1. Put 50 parts by weight of Golden Camellia, 10 parts by weight of Panda Dahai, 9 parts by weight of mint leaves, 10 parts by weight of honeysuckle and 7 parts by weight of licorice at a temperature of 60 ° C and a vacuum of -0.09 MPa. Vacuum-dry until the moisture content is less than 10%, and then pulverize to 50 mesh with a pulverizer respectively to obtain golden camellia powder, fat sea powder, peppermint powder, honeysuckle powder and licorice powder for later use; because different pulverizers are used for different raw materials, they are separated Crush and then mix.

[0094] Step 2: Mix the camellia powder, the fat sea powder, the peppermint powder, the honeysuckle powder and the licorice powder, put them in 150 parts by weight of water, and then add 0.015 parts by weight of cellulase and 0.015 parts by weight of pectinase, adjusted the pH value to 6 with citric acid, stir...

Embodiment 3

[0130] A preparation method of throat lozenges, comprising the following steps:

[0131]Step 1. Put 45 parts by weight of Golden Camellia, 7 parts by weight of Panda Dahai, 8 parts by weight of mint leaves, 9 parts by weight of honeysuckle and 6 parts by weight of licorice at a temperature of 55 ° C and a vacuum of -0.08 MPa. Vacuum-dried until the water content is less than 10%, and then crushed to 40 mesh with a pulverizer respectively to obtain golden camellia powder, fat sea powder, peppermint powder, honeysuckle powder and licorice powder for later use; because the pulverizers used for different raw materials are different, they are separated Crush and then mix.

[0132] Step 2: Mix the camellia powder, the fat sea powder, the peppermint powder, the honeysuckle powder and the licorice powder, put them in 125 parts by weight of water, and then add 0.012 parts by weight of cellulase and 0.011 parts by weight of pectinase, adjusted the pH value to 6 with citric acid, stirre...

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Abstract

The invention discloses a method for preparing a throat lozenge. The method is as below: pulverizing golden camellia, scaphium scaphigerum, mint leaves, honeysuckle and licorice, mixing and conducting enzymatic hydrolysis to obtain an enzymatic hydrolyzate; repeatedly solidifying and melting the enzymatic hydrolyzate 5-7 times, concentrating in vacuum to obtain a concentrated liquid, conducting carbon dioxide supercritical extraction to obtain an extract; mixing the extract, 3-5 parts by weight of Mogrosides, 10-20 parts by weight of maltose syrup and 3-5 parts by weight of water, then stirring evenly, allowing standing for 3-4 h, cutting the mixture into small blocks with length and width of 2-4 cm, then conducting vacuum drying on the small blocks to moisture content of less than 4%, crushing to 40-60 mesh, then adding edible alcohol, and evenly mixing to obtain a fine powder; and compacting and shaping the fine powder by a tablet press. The present invention uses the supercritical carbon dioxide extraction method to effectively prevent oxidation and dissipation of heat-sensitive materials, has no solvent residue, and improves the quality of the throat lozenge.

Description

technical field [0001] The invention relates to a lozenge. More specifically, the present invention relates to a preparation method of throat lozenges. Background technique [0002] Sore throat is a clinical symptom of oropharynx and hypopharynx lesions. Anyone suffering from acute or chronic pharyngitis, hypopharynx, tonsillitis, peritonsillar abscess, herpetic angina, ulcerative membrane pharyngitis, throat abscess, etc. All can cause throat redness and pain, swallowing discomfort, hoarseness, and generally last for a long time, seriously affecting the quality of life. [0003] At present, there are many medicines on the market for clearing and moistening the throat. The main effects are to clear away heat and relieve fire, reduce swelling and relieve pain. Some Chinese medicinal materials will be introduced in the process of making lozenge lozenges. When extracting the active ingredients in Chinese medicinal materials, they are mainly obtained after treatment by leachin...

Claims

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Application Information

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IPC IPC(8): A61K36/82A61K9/20A61K47/26A61P11/04A61J3/10
CPCA61K36/82A61J3/10A61K9/0056A61K9/2018A61K36/185A61K36/355A61K36/484A61K36/534A61K2236/19A61K2236/37A61K2300/00
Inventor 马占平郭中河王锋
Owner 马占平
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