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Traditional Chinese medicine composition for treating bronchitis and preparation method thereof

A technology of bronchitis and composition, which is applied in the field of traditional Chinese medicine composition for treating bronchitis and its preparation, can solve problems such as side effects and easy recurrence, achieve good curative effect, avoid recurrence, and restore immune function

Inactive Publication Date: 2016-07-06
张鸿
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, a large number of antibiotics such as erythromycin and cephalosporins are mainly used for the treatment of bronchitis, expectorants such as Tankejing, antispasmodic and antiasthmatic drugs such as aminophylline, etc., but these drugs are prone to drug resistance and are not easy to treat. Solve the problem fundamentally, and it is easy to relapse after stopping the drug, and has certain side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] (1) a Chinese medicine for the treatment of bronchitis, which is formed by the proportioning of the following raw materials by weight:

[0034] 30 parts of bamboo yellow, 25 parts of heart grass, 20 parts of ground loquat, 15 parts of cardamom shell, 15 parts of rhododendron orchid, 10 parts of wild wild wild rice, 10 parts of bellows root, 10 parts of white flower gentian, 10 parts of mimosa, white Uncaria 5 parts, big tail shake 5 parts.

[0035] (2) Preparation method:

[0036] In the first step, the sage and loquat are mixed in proportion, extracted twice with n-propanol with an alcohol concentration of 70% equivalent to twice the mass of the mixture, and the filtrates are combined, concentrated under reduced pressure, dried and pulverized into powder, and then Purify 1-2 times with ethanol, combine the extracts, recover ethanol under reduced pressure and concentrate to a paste with a relative density of 1.21-1.24 at 60°C, dry and pulverize into powder;

[0037] T...

Embodiment 2

[0041] (1) a kind of Chinese medicine for the treatment of bronchitis is formed by the proportioning of following raw materials by weight: with embodiment 1.

[0042](2) Preparation method:

[0043] In the first step, the sage and loquat are mixed in proportion, extracted twice with n-propanol with an alcohol concentration of 70% equivalent to twice the mass of the mixture, and the filtrates are combined, concentrated under reduced pressure, dried and pulverized into powder, and then Purify once with ethanol, combine the extracts, recover ethanol under reduced pressure and concentrate to a paste with a relative density of 1.21-1.24 at 60°C, dry and pulverize into powder;

[0044] In the second step, cardamom shells, rhododendron orchids, wild wild wild rice, and bellows are extracted twice with n-propanol with an alcohol concentration of 80%, the extracts are combined, concentrated under reduced pressure, dried, and pulverized into powder, and the pulverized The powder is dis...

Embodiment 3

[0048] 1. Long-term toxicity test process:

[0049] Apply Wistar rats (Beijing Weitong Lihua Experimental Animal Technology Co., Ltd. provides) experimental medicine is set to high, medium and low three dosages, be respectively the capsule 8g / kg, 4g / kg, 2g of embodiment 1 formula / kg. Calculated according to the human dose of 0.1g / kg / day tablet, it is 80 times, 40 times and 20 times of the effective dose for human respectively; another control group is set up, which is given continuously for 90 days and 180 days by intragastric administration and part of the animals are withdrawn for 10 days. Days later, the effects on various physiological and biochemical indicators of rats were observed. The experimental results show that: continuous oral administration of different doses to rats for 180 days has no effect on the food intake and weight growth of the rats. No significant toxic effects were found on liver and kidney function. There was no obvious effect on blood routine, bl...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating bronchitis.The traditional Chinese medicine composition is prepared from herb of tripterospermum cordifolium (Marq.) H.Smith, herb of canscora lucidissima, herb of ficus tikoua, round cardamom fruit shells, pseudobulbs of cremastra mirata A.Gray, herb of Indian aeginetia, buttonbush roots, herb of gentiana purdomii Marq., herb of mimosa pudica, ramulus uncariae cum unis and herb of Indian heliotrope.The invention further discloses a preparation method of the traditional Chinese medicine composition.The traditional Chinese medicine composition has the advantages of being good in treatment effect, low in cost, high in cure rate, free of adverse reaction and the like on bronchitis treatment.The traditional Chinese medicine composition can comprehensively harmonize the functions of the fiver internal organs, thoroughly eliminate the lesions, gradually recover the immune function to recover a healthy atmosphere and prevent relapse of the chronic bronchitis.

Description

technical field [0001] The invention relates to a medical preparation, in particular to a traditional Chinese medicine composition for treating bronchitis and a preparation method thereof. Background technique [0002] Bronchitis refers to chronic non-specific inflammation of the trachea, bronchial mucosa and surrounding tissues. Clinically, it is characterized by long-term cough, expectoration or accompanied by wheezing and recurrent attacks. Chronic cough, sputum or accompanied by wheezing, the attack lasts for 3 months every year, more than 2 years in a row, and other heart and lung diseases can be ruled out and repeated attacks, some patients can develop obstructive emphysema, chronic pulmonary heart disease sick. At present, a large number of antibiotics such as erythromycin and cephalosporins are mainly used for the treatment of bronchitis, expectorants such as Tankejing, antispasmodic and antiasthmatic drugs such as aminophylline, etc., but these drugs are prone to ...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P11/00
CPCA61K36/51A61K9/0019A61K9/08A61K9/4858A61K36/30A61K36/48A61K36/515A61K36/60A61K36/64A61K36/74A61K36/898A61K36/9064A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 张鸿王辉刘艳梅
Owner 张鸿
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