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A traditional Chinese medicine composition for treating ulcerative colitis and its preparation method

A technology for ulcerative colitis and a composition is applied in the field of traditional Chinese medicine compositions for the treatment of ulcerative colitis and the field of preparation thereof, which can solve the problems of high recurrence rate, obvious side effects, poor effect of ulcerative colitis, etc., and reduce edema. , good therapeutic effect, the effect of alleviating the pain of the disease

Active Publication Date: 2019-06-28
NANJING HAILING TRADITIONAL CHINESE MEDICINE RES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For this reason, the technical problem to be solved by the present invention is that the medicines in the prior art are not effective in treating ulcerative colitis, have a high recurrence rate and obvious side effects, and then provide a drug that has a good effect in treating ulcerative colitis and has a low recurrence rate. As well as the traditional Chinese medicine composition with no obvious side effects and its preparation method

Method used

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  • A traditional Chinese medicine composition for treating ulcerative colitis and its preparation method
  • A traditional Chinese medicine composition for treating ulcerative colitis and its preparation method
  • A traditional Chinese medicine composition for treating ulcerative colitis and its preparation method

Examples

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Effect test

Embodiment 1

[0072] Embodiment 1 granular dosage form

[0073] The Chinese medicine composition for the treatment of ulcerative colitis of the present embodiment, its formula is as follows:

[0074]Coptidis 7g, Paojiang 11g, Sophora flavescens 7g, Panax notoginseng 8g, Qingdai 4g, Muxiang 8g, Burnet charcoal 7g and roasted licorice 5g.

[0075] The Chinese medicine composition is prepared into granules according to the following steps:

[0076] (a) Mix Coptis rhizome, Paojiang, Sophora flavescens, Panax notoginseng, Indigo Daisy, Woody Fragrance, Burnet charcoal, and roasted licorice according to the selected parts by weight, add water to decoct twice, add 570ml of water for the first time, and decoct After 1.5 hours, add 456ml of water for the second time, decoct for 1 hour, filter, combine the filtrate, let it stand overnight, take the supernatant and concentrate it to an extract with a relative density of 1.2-1.25 at 60°C;

[0077] (b) Take the extract and add conventional pharmacy ex...

Embodiment 2

[0078] Embodiment 2 capsule dosage forms

[0079] The Chinese medicine composition for the treatment of ulcerative colitis of the present embodiment, its formula is as follows:

[0080] Coptidis 11g, Paojiang 7g, Sophora flavescens 7g, Panax notoginseng 8g, Qingdai 11g, Muxiang 4g, Burnet charcoal 11g and Zhilicorice 1g.

[0081] The Chinese medicine composition is prepared into granules according to the following steps:

[0082] (a) Mix Coptidis Rhizome, Pao Jiang, Sophora Sophora, Panax notoginseng, Indigo Daisy, Woody Fragrance, Burnet Charcoal and Radix Glycyrrhizae according to the weight of raw materials selected above, add water to decoct twice, and add 12 times the weight of the drug for the first time water, decoct for 2 hours, add 10 times the drug weight water for the second time, decoct for 1.5 hours, filter, combine the filtrate, let it stand overnight, take the supernatant and concentrate it to an extract with a relative density of 1.2-1.25 at 60°C ;

[0083] ...

Embodiment 3

[0084] Embodiment 3 pill form

[0085] The Chinese medicine composition for the treatment of ulcerative colitis of the present embodiment, its formula is as follows:

[0086] Coptidis 9g, Paojiang 9g, Sophora flavescens 9g, Panax notoginseng 6g, Qingdai 9g, Muxiang 6g, Burnet charcoal 9g and roasted licorice 3g.

[0087] Described Chinese medicine composition is prepared into pill according to the following steps:

[0088] (a) According to the weight of raw materials selected above, take Coptis rhizome, Paojiang, Sophora flavescens, Panax notoginseng, Qingdai, woody incense, Burnet charcoal and roasted licorice, add water to decoct twice, and add 8 times the medicine for the first time weight of water, decoct for 1.5 hours, add 6 times the drug weight water for the second time, decoct for 2 hours, filter, combine the filtrate, let it stand overnight, take the supernatant and concentrate it to 60 ° C with a relative density of 1.2-1.25. paste;

[0089] (b) Take the extract, ...

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Abstract

A traditional Chinese medicine composition for treating ulcerative colitis (UC), the composition comprising the following raw materials: 7-11 parts by weight of coptis, 7-11 parts by weight of baked ginger, 7-11 parts by weight of radix sophorae flavescentis, 4-8 parts by weight of notoginseng, 4-11 parts by weight of indigo naturalis, 4-8 parts by weight of costustoot, 7-11 parts by weight of carbonized sanguisorba root and 1-5 parts by weight of honey-fried licorice root. The traditional Chinese medicine composition has a good UC treatment effect, low relapse rate and few side effects, is beneficial to clean the intestinal canal, warm the stomach and tone the spleen, mildly regulate cold and heat, disperse blood stasis and stop bleeding, thus relieving the pain of diseases, improving quality of life, and prolonging life.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine composition for treating ulcerative colitis and a preparation method thereof. Background technique [0002] Ulcerative colitis (UC) is a chronic non-specific inflammatory disease of the colon and rectum with unknown etiology, and the lesions are limited to the mucosa and submucosa of the large intestine. The lesions are mostly located in the sigmoid colon and rectum, and can also extend to the descending colon, or even the entire colon. , Chinese medicine belongs to the categories of "intestinal dysentery" and "dysentery". The clinical manifestations of ulcerative colitis can have many forms. Mucus pus and blood are the important manifestations of the active stage of the disease. Other symptoms include abdominal pain, nausea, vomiting, weight loss, tenesmus, etc., sometimes accompanied by peripheral arthritis, ep...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K36/739A61K36/718A61K36/704A61K36/489A61K36/484A61K36/315A61K36/285A61K36/258A61K36/19A61K9/48A61K9/20A61K9/14A61K9/02A61P1/04
CPCA61K9/0053A61K36/258A61K36/315A61K36/484A61K36/489A61K36/718A61K36/739A61K36/88A61K36/9068A61P1/04
Inventor 李军祥
Owner NANJING HAILING TRADITIONAL CHINESE MEDICINE RES CO LTD
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