A kind of preparation method of effervescent tablet
A technology of effervescent tablets and polyethylene glycol, applied in the field of preparation of pharmaceutical dosage forms, can solve the problems of difficult industrial production, extended shelf life, and short shelf life, and achieve the effect of long shelf life, extended shelf life, and simple method
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0027] 1, the effervescent tablet of the present embodiment, comprises the following raw materials by 3kg as base material: ginger powder 0.06kg, PVP-K300.03kg, sodium bicarbonate 0.30kg, tartaric acid 0.27kg, PEG60000.15kg, salt 2.16kg, micropowder Silica gel 0.03kg, absolute ethanol 0.14L.
[0028] Include the following steps:
[0029] Step 1, heat 0.09kg of PEG6000 to 70°C to dissolve, then dilute with 0.03L of ethanol, coat 0.3kg of sodium bicarbonate, and coat the alkali source with a layer of PEG film for use;
[0030] In step 2, 0.06kg of PEG6000 is heated to 70°C to dissolve, then diluted with 0.02L of ethanol, and 0.27kg of tartaric acid is coated, so that the acid source is coated with a layer of PEG film for use;
[0031] Step 3, fully mixing the coated acid source and alkali source, it is A;
[0032] Step 4, dissolving 0.01kg PVP-K30 with 0.03L dehydrated alcohol, and coating A with it to obtain effervescent particles coated with a double-layer organic film layer...
Embodiment 2
[0039] The effervescent tablet of the present embodiment includes the following raw materials based on 3kg: ginger powder 0.06kg, PVP-K300.06kg, sodium bicarbonate 0.30kg, tartaric acid 0.27kg, PEG40000.15kg, salt 2.13kg, micropowder silica gel 0.03 kg, anhydrous ethanol 0.35L.
[0040] Include the following steps:
[0041] Step 1, heat 0.09kg of PEG4000 to 60°C to dissolve, then dilute with 0.03L of ethanol, coat 0.3kg of sodium bicarbonate, and coat the alkali source with a layer of PEG film for use;
[0042] In step 2, 0.06kg of PEG4000 is heated to 60°C to dissolve, then diluted with 0.02L of ethanol, and 0.27kg of tartaric acid is coated, so that the acid source is coated with a layer of PEG film for use;
[0043] Step 3, fully mixing the coated acid source and alkali source, it is A;
[0044] Step 4, dissolving 0.01kg PVP-K30 with 0.05L absolute ethanol, and coating A with it to obtain effervescent particles coated with a double-layer organic film layer;
[0045] Step...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com