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Traditional Chinese medicine for treating liver stagnation and damp heat type dysmenorrhoea, and preparation method thereof

A technology for primary dysmenorrhea and liver stagnation and damp-heat, which is applied in the field of pharmacy to achieve the effect of convenient administration and strong pertinence

Inactive Publication Date: 2016-05-11
THE THIRD PEOPLES HOSPITAL OF QINGDAO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Severe: unbearable pain in the lower abdomen during menstruation or before and after, restlessness, seriously affecting work, study and daily life, must rest in bed, accompanied by waist pain, pale complexion, cold sweat, cold limbs, vomiting and diarrhea, or anal Bloating, no obvious relief with painkilling measures

Method used

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Examples

Experimental program
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Effect test

preparation example Construction

[0040] Wherein, when the dosage form of described Chinese medicine is granule, its preparation method comprises the following steps:

[0041] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% relative to the mixture 4 to 8 times, heat to boiling and reflux for 3 to 5 hours, filter, and use the reflux liquid as a solvent , taking the filter residue as the solute, slowly percolating at a rate of 1-2 ml per minute by percolation method, collecting the percolating liquid, and then concentrating under reduced pressure to 50-60 ℃ under the vacuum degree of 0.06-0.09Mpa, the relative density is 1.04 The paste of ~1.10 is spray-dried, the inlet air temperature of the spray dryer is 160-175 °C, and the outlet air temperature is 80-85 °C, and then pulverized into powder to make dry paste powder;

[0042] Step 2: adding 0.2-0.4 times the mass of sucrose powder and 0.1-0.2 times the mass of the dry paste powder t...

Embodiment 1

[0048] Example 1: Granules

[0049] Take 140g Tonghuahua, 160g Niujiaoqi, 280g Qingtongcao, 120g mountain sorghum, 200g black soybean, 300g barmao root, 80g fiber crown vine, 100g drifting bean, 200g red fragrant tree, 120g water loquat, 150g horse locust fruit, white 160g of thorn flower, 260g of half column flower and 180g of sweet potato root.

[0050] Its preparation method comprises the following steps:

[0051] Step 1: Mix the raw medicinal materials according to the stated ratio, add 7 times of ethanol with an alcohol concentration of 95% relative to the mixture, heat to boiling and reflux for 3 hours, filter, use the reflux liquid as the solvent, and use the filter residue as the solute, using The percolation method slowly percolates at a rate of 2ml per minute, collects the percolation liquid, and then decompresses and concentrates it under a vacuum of 0.08Mpa to a paste with a relative density of 1.07 at 55°C, spray drying, and the air inlet of the spray dryer The ...

Embodiment 2

[0053] Example 2: Powder

[0054] Take 160g Tonghuahua, 190g Niujiaoqi, 250g Qingtongcao, 140g mountain sorghum, 220g black soybean, 260g barmao root, 120g fiber crown vine, 140g drifting bean, 240g red fragrant tree, 160g water loquat, 180g horse locust fruit, white 140g of thorn flower, 280g of half column flower and 150g of sweet potato root.

[0055] Its preparation method comprises the following steps:

[0056] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 95% relative to 4 times the mass of the mixture, heat under reflux for 2 hours, extract, and filter to obtain a first extract; filter the obtained medicinal residues Then add 85% ethanol with an alcohol concentration of 2 times the mass of the medicinal residues, heat under reflux for 2 hours, extract, and filter to obtain a second extraction solution; combine the first extraction solution and the second extraction solution, co...

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Abstract

The invention provides a traditional Chinese medicine for treating liver stagnation and damp heat type dysmenorrhoea, and a preparation method thereof. The traditional Chinese medicine comprises Flower-bud of Rice paperplant, Rodgersia aesculifolia Batal., Helwingia japonica (Thunb.), Sorbaria Sorbifolia, black beans, rhizome of Miscanthus sacchariflorus (Maxim.) Benth, Gongronema nepalense (Wall.) Decne., Seed of Pigeon Vetch, Bark of Common Anneslea, Root of Common Saurauia, root of Beautiful cotoneaster, Root of Vetchleaf Sophora, herb of Hemigraphis procumbens (Lour.) Merr. and digua fig root. The traditional Chinese medicine using traditional Chinese medicine theory, and has the advantages of strong pertinence, convenient administration, good treatment effect and no toxic or side effects in treatment of the liver stagnation and damp heat type dysmenorrhoea.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating primary dysmenorrhea of ​​liver stagnation and damp-heat type and a preparation method. Background technique [0002] Primary dysmenorrhea, or functional dysmenorrhea, refers to pain during menstruation, often spasmodic, concentrated in the lower abdomen. Other symptoms include headache and fatigue, dizziness, nausea and vomiting, diarrhea, low back and leg pain, which are very common symptoms in young women. Primary dysmenorrhea is not accompanied by obvious pelvic organic diseases. [0003] Primary pain often occurs in young women. It begins several months after menarche (6 to 12 months), and the incidence begins to decline after the age of 30. Pain often begins before or after menstruation, and continues during the menstrual period. In the first 48 to 72 hours, the pain is often spasmodic and sometimes so severe that it is necessar...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P15/00A61P29/00
CPCA61K9/146A61K9/1652A61K36/185A61K36/19A61K36/25A61K36/27A61K36/40A61K36/48A61K36/489A61K36/60A61K36/73A61K36/82A61K36/899A61K2236/333A61K2236/51A61K2300/00
Inventor 刘青
Owner THE THIRD PEOPLES HOSPITAL OF QINGDAO
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