Traditional Chinese medicine composition for treating colon cancer

A composition and technology of colon cancer, applied in the field of medicine, can solve the problems of difficult clinical treatment, and there is no special effective method to completely cure colon cancer, and achieve significant curative effect, no toxic side effects, and high efficiency

Inactive Publication Date: 2016-05-04
席新进
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When colon cancer is formed, its clinical treatment is also very difficult, mainly because the cause of colon cancer has not been clarified, so there is still no effective way to completely cure colon cancer

Method used

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  • Traditional Chinese medicine composition for treating colon cancer
  • Traditional Chinese medicine composition for treating colon cancer
  • Traditional Chinese medicine composition for treating colon cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Weigh 10 grams of cat ginseng, 12 grams of milk seed root, 15 grams of hawthorn root, 12 grams of grape root, 12 grams of red vine, 15 grams of flying crane, 10 grams of Hedyotis diffusa, 12 grams of Resurrection Grass, and 10 grams of vine pear root. 10 grams of Buddleia, 12 grams of Plantago, 10 grams of Hongmuxiang, 10 grams of Baimuxiang, 15 grams of Bamboo Leaf, 12 grams of Panax notoginseng, 15 grams of Polygonum cuspidatum, 10 grams of Atractylodes macrocephala, 10 grams of Tiankui Seed, 12 grams of Chuanxiong 10 grams of Danshen, 10 grams of Daqingye, 10 grams of barbata, 8 grams of pearl umbrella, 12 grams of lobelia, 10 grams of single flower, 12 grams of seven leaves, 12 grams of baby vine, mountain conch 10 grams and 10 grams of thistle, crushed, added 100,000 ml of water, heated under reflux for 3 hours, filtered, the filtrate was cooled to room temperature, and then filtered through a 0.22 μm microporous membrane to obtain solution 1.

Embodiment 2

[0017] Weigh out 0.1 g of Add 80,000 ml of sterile water, sonicate for 30 minutes, and then filter through a 0.22 μm microporous membrane to obtain solution 2.

experiment example

[0019] MTT (purchased from Sigma Company) was dissolved in normal saline, prepared into a working solution of 5 mg / mL, and stored at -20°C; dimethylsulfoxide (DMSO) was produced by Xi'an Chemical Reagent Factory and was analytically pure.

[0020] Principle of MTT method

[0021] MTT is an acceptable H + yellow dye. In the mitochondrial respiratory chain of living cells, succinate dehydrogenase and cytochrome C can cleave the tetrazolium ring of MTT to produce blue-purple formazan crystals. Dead cells do not contain this dehydrogenase. The amount of Formazan crystals generated is directly proportional to the number of viable cells, and the DMSO solution of the crystals has a maximum absorption peak at 570nm. Therefore, the effect of the drug on cell proliferation can be evaluated by detecting the amount of formazan crystals.

[0022] testing method

[0023] Take the tumor cells in the logarithmic growth phase and adjust the cell density to 2×10 5 cells / mL, add 200 μL per ...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating a colon cancer. The traditional Chinese medicine composition for treating the colon cancer is prepared from, by weight, 10 parts of valvate actinidia roots, 12 parts of Elaeagnus umbellala Thunb, 15 parts of hawthorn roots, 12 parts of grape roots, 12 parts of sargentgloryvine stems, 15 parts of auriculate swallowwort stems and leaves, 10 parts of a spreading hedyotis herb, 12 parts of a whorlleaf stonecrop herb, 10 parts of Chinese actinidia roots, 10 parts of a lindley butterflybush herb, 12 parts of semen plantaginis, 10 parts of longpeduncle kadsura roots, 12 parts of lignum aquilariae resinatum, 15 parts of lophatherum gracile, 12 parts of pseudo-ginsengs, 15 parts of giant knotweeds, 10 parts of white atractylodes rhizomes, 10 parts of radix semiaquilegiae, 12 parts of Szechwan lovage rhizomes, 10 parts of salvia miltiorrhiza, 10 parts of folium isatidis, 10 parts of a barbed skullcap herb, 8 parts of ardisia maculosa Mez, 12 parts of lobelia chinensis, 10 parts of a flabellate hemipilia herb, 12 parts of paris polyphylla, 12 parts of tylophora ovata, 10 parts of lance asiabell roots and 10 parts of circium japonicum. The medicines of the traditional Chinese medicine composition have the effects of invigorating blood circulation, softening hard mass, eliminating phlegm, removing stasis, nourishing yin and blood, invigorating spleen to remove dampness, detoxifying and resisting to cancers, and the traditional Chinese medicine composition is remarkable in colon cancer treating effect, high in effective rate and free of toxic and side effects, can be directly used for treating the effective rate and can be also used for postoperative adjunctive treatment of the colon cancer.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating colon cancer. Background technique [0002] Colorectal cancer (CRC) is one of the common malignant tumors. Its incidence rate of malignant tumors has risen to the third place in the world, and its mortality rate ranks second among malignant tumors. The mortality rate of colon cancer in my country ranks fifth among malignant tumors. , seriously endangering human health. Colon cancer originates from intestinal epithelial cells, through a series of complex genetic and epigenetic changes, accumulated over a long period of time, and finally undergoes malignant transformation of cells, forming a specific type of cancer. When colon cancer develops, its clinical treatment is also very difficult, mainly because colon cancer has no clear cause, so there is still no effective method to completely cure colon cancer. During the occurrence and de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K31/536A61P35/00
CPCA61K36/185A61K31/536A61K36/11A61K36/195A61K36/236A61K36/258A61K36/27A61K36/28A61K36/284A61K36/315A61K36/34A61K36/344A61K36/41A61K36/537A61K36/539A61K36/56A61K36/57A61K36/68A61K36/704A61K36/71A61K36/734A61K36/748A61K36/79A61K36/835A61K36/855A61K36/87A61K36/896A61K36/898A61K36/899A61K2300/00
Inventor 席新进
Owner 席新进
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