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Traditional Chinese medicine composition for treating ADHD (Attention Deficit Hyperactivity Disorder) and preparation method thereof

A kind of ADHD and composition technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of complex and changeable factors of ADHD and difficult symptomatic treatment, so as to reduce the dosage of drugs and improve the curative effect Visible, Affordable Results

Inactive Publication Date: 2016-03-30
WUHAN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the complex and changeable factors causing ADHD in children, it is difficult to treat the symptoms. Therefore, it is an urgent task to develop a new traditional Chinese medicine for the treatment of ADHD in children.

Method used

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  • Traditional Chinese medicine composition for treating ADHD (Attention Deficit Hyperactivity Disorder) and preparation method thereof
  • Traditional Chinese medicine composition for treating ADHD (Attention Deficit Hyperactivity Disorder) and preparation method thereof
  • Traditional Chinese medicine composition for treating ADHD (Attention Deficit Hyperactivity Disorder) and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Prescription: Pseudostellaria 120g, Poria cocos 150g, Atractylodes macrocephala 150g, white peony root 150g, Uncaria 150g, scorpion 40g, tangerine peel 80g, pinellia chinensis 75g, hawthorn 150g, licorice 40g, gallinacea 130g.

[0021] This Chinese medicine preparation method is as follows:

[0022] a. Extraction of volatile oil: Take 150g of Atractylodes macrocephala, 80g of tangerine peel, add 690ml of water, soak for 1 hour, reflux distillation for 7 hours to obtain 1.0ml of volatile oil for later use, and collect the filtered mother liquor and medicinal residues in separate vessels after distillation.

[0023] b Hawthorn and Radix Glycyrrhizae extraction preparation: add water 4200ml to the dregs obtained in step a, 150g hawthorn, 40g Radix Glycyrrhizae, decoct 2 times, each time for 2 hours; then combine the decoction twice, filter, filtrate and step a Combine the mother liquors; concentrate the above mixed solution until the concentration of the crude drug is abou...

Embodiment 2

[0030] Prescription: Pseudostellaria 60g, Poria cocos 50g, Atractylodes macrocephala 50g, white peony 50g, Uncaria 50g, scorpion 10g, tangerine peel 20g, pinellia 15g, hawthorn 50g, licorice 10g, gallinacea 70g.

[0031] This Chinese medicine preparation method is as follows:

[0032]a. Extraction of volatile oil: Take 50g of Atractylodes macrocephala, 20g of tangerine peel, add 210ml of water, soak for 1 hour, reflux distillation for 7 hours to obtain 0.4ml of volatile oil for later use, and collect the filtered mother liquor and medicinal residues in separate vessels after distillation.

[0033] b hawthorn and roasted licorice extraction preparation: add 1300ml of water to the dregs obtained in step a, 50g of hawthorn and 10g of roasted licorice, decoct twice for 2 hours each time; combine the decoctions, filter, and merge the filtrate with the mother liquor in step a; Concentrate the mixed solution until the crude drug concentration is about 0.5g / ml, let it cool to room tem...

Embodiment 3

[0040] Prescription: Pseudostellaria 100g, Poria cocos 100g, Atractylodes macrocephala 100g, white peony 100g, Uncaria 100g, scorpion 30g, tangerine peel 50g, pinellia 50g, hawthorn 100g, licorice 30g, gallinacea 100g.

[0041] This Chinese medicine preparation method is as follows:

[0042] a. Extraction of volatile oil: Take 100g of Atractylodes macrocephala, 50g of tangerine peel, add 450ml of water, soak for 1 hour, and reflux distillation for 7 hours to obtain 0.7ml of volatile oil for later use.

[0043] b Hawthorn and Radix Glycyrrhizae Extraction and Preparation: Add 2800ml of water to the dregs obtained in step a, 100g of Hawthorn, and 30g of Radix Glycyrrhizae, decoct twice for 2 hours each time; combine the decoctions, filter, and combine the filtrate with the mother liquor in step a Concentrate the mixed solution to a crude drug concentration of about 0.5g / ml, let cool to room temperature, and slowly add ethanol to the solution while stirring, so that the final vol...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating ADHD (Attention Deficit Hyperactivity Disorder) and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 60 to 120 parts of radix pseudostellariae, 50 to 150 parts of poria cocos, 50 to 150 parts of rhizoma atractylodis macrocephalae, 50 to 150 parts of radix paeoniae alba, 50 to 150 parts of uncaria tomentosa, 10 to 40 parts of scorpio, 20 to 80 parts of pericarpium citri reticulatae, 15 to 75 parts of rhizoma pinellinae praeparata, 50 to 150 parts of hawthorn, 10 to 40 parts of radix glycyrrhizae preparata and 70 to 130 parts of endothelium corneum gigeriae galli. The preparation method of the traditional Chinese medicine composition comprises the steps of a, extracting rhizoma atractylodis macrocephalae and pericarpium citri reticulatae volatile oil; b, preparing dry extract powder of hawthorn and radix glycyrrhizae preparata; c, preparing sediment of radix pseudostellariae and poria cocos; d, preparing dry extract powder of radix paeoniae alba, uncaria tomentosa, scorpio and rhizoma pinellinae praeparata; e, preparing endothelium corneum gigeriae galli powder; f, preparing a volatile oil and beta-cyclodextrin inclusion compound; g, granulating by mixing active dry extract powder, the sediment and the endothelium corneum gigeriae galli powder with sucrose powder and dextrin. The traditional Chinese medicine composition for treating ADHD, disclosed by the invention, is simpler in preparation technology and has the advantages that the treating effect is remarkable, the dosage is small, the side effects are small, and the like; meanwhile, the medicine dosage can be greatly reduced, the traditional Chinese medicine composition is more suitable for a child to take, and the cost is preiswert.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating ADHD in children and a preparation method thereof. Background technique [0002] ADHD is clinically also known as mild brain dysfunction dysfunction syndrome. The disease often occurs in premature children, mainly manifested as inattention, frequent activities, and poor self-control such as emotional agitation, so it is also called attention-deficit hyperactivity disorder. influences. It is generally believed that ADHD is a behavioral disease caused by genetic, psychological, environmental and other factors, and is the result of the interaction of psychological, biological, environmental and social factors. [0003] The treatment of children with ADHD mainly includes drug therapy and psychotherapy, and sometimes it is necessary to combine the two in order to exert the best therapeutic effect. At pres...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61P25/14A61P25/00A61K35/57A61K35/646
CPCA61K36/36A61K9/1652A61K35/57A61K35/646A61K36/076A61K36/284A61K36/484A61K36/65A61K36/71A61K36/734A61K36/74A61K36/752A61K36/8888A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 黄志军宋畅朱立彬许沛虎徐海星陈骞鲁娜梁鹏
Owner WUHAN UNIV OF TECH
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