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Application of zanthoxylum oil in preparing drugs or health-care products for preventing and/or treating virus flu

A technology for viral influenza and prickly ash essential oil, applied in antiviral agents, medical preparations containing active ingredients, food science, etc., can solve the problems of not recommending universal vaccination, ineffective effect, and reducing morbidity.

Inactive Publication Date: 2016-03-30
LIAONING NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western and domestic clinical anti-influenza drugs are often ineffective and have relatively large side effects
For example: antibiotics only have the effect of killing or inhibiting bacteria, but are powerless against viruses, and the abuse of antibiotics can also lead to drug resistance; antiviral drugs can only kill viruses in a targeted manner, but the virus has a strong ability to mutate; chemical drugs treat primitive The virus is effective, but it does not improve the body's immunity, and it is not strong against mutated viruses, and it is easy to develop drug resistance
The problems with influenza vaccines are: first, the effect of influenza vaccines is still unsatisfactory so far. Generally, it can only reduce the incidence rate, but still cannot control the epidemic.
Second, there is no so-called "universal" vaccine, and the components of the vaccine must correspond to the virus strain to play its due role
Third, the effect of the influenza vaccine is limited, and the immunity is not long-lasting. Therefore, it is generally not recommended for the general public to be vaccinated. sick people) vaccination
At present, there are no patents and literature reports on the use of Zanthoxylum bungeanum essential oil for anti-influenza virus

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Pepper essential oil granules

[0026] prescription

[0027] Pepper essential oil 10g

[0028] Beta Cyclodextrin 30g

[0029] Dextrin 100g

[0030] Preparation Process

[0031] Put the cyclodextrin in a beaker, add appropriate amount of water, heat in a water bath at 60°C to make a saturated solution, drop the pepper essential oil into the saturated cyclodextrin aqueous solution, stir for 2 hours, take out the beaker, place it at room temperature for 24 hours, and filter To obtain the inclusion compound of Zanthoxylum bungeanum essential oil, dry it in an oven, add dextrin, use starch slurry as a binder, granulate, dry, and granulate to obtain Zanthoxylum essential oil granules.

Embodiment 2

[0033] Pepper Essential Oil Tablets

[0034] Pepper essential oil 5g

[0035] Diatomaceous earth 20g

[0036] Compressible starch 50g

[0037] Preparation Process

[0038] Take pepper essential oil, spray it evenly on the surface of diatomaceous earth and let it absorb completely, add compressible starch, mix evenly, and directly compress into tablets.

Embodiment 3

[0040] Zanthoxylum essential oil oral liquid

[0041] Pepper essential oil 50g

[0042] 10% ethanol 500ml

[0043] Preparation Process

[0044] Take pepper essential oil, add it to 10% ethanol solution, dissolve it, pack it separately, and get it.

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PUM

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Abstract

The invention discloses the specific application of zanthoxylum oil. Zanthoxylum oil is a zanthoxylum source secondary metabolism product and is a volatile oily liquid substance which has a small molecular weight, can be steamed out along with vapor, and has a certain smell in zanthoxylum. Modern pharmacological experiments prove that zanthoxylum oil has sterilizing, antineoplastic, insecticidal, smooth muscle contraction restraining, anesthetizing and antioxidant functions, and has certain new drug development value. However, there is no patent or document report about using zanthoxylum oil for resisting epidemic virus flu currently. The specific application of zanthoxylum oil is the application of zanthoxylum oil in preparing drugs or health-care products for preventing and / or treating virus flu, the application range of zanthoxylum oil is increased on one hand, a new idea is provided for preventing and / or treating virus flu on the other hand, and tests prove that zanthoxylum oil has a good treatment effect on flu virus.

Description

technical field [0001] The present invention relates to a specific application of Zanthoxylum bungeanum essential oil, in particular to the application of Zanthoxylum bungeanum essential oil in the preparation of medicines or health care products for preventing and / or treating viral influenza. Background technique [0002] Influenza (abbreviated as influenza) is an acute respiratory infection caused by influenza virus, and it is also a highly contagious and fast-spreading disease. Influenza viruses belong to the Orthomyxoviridae family; according to the current virological classification, Orthomyxoviruses can be divided into five categories. However, there are three types of human-related ones that have been discovered so far. Influenza A virus is also called influenza A virus, Influenza B virus is also called influenza B virus, and Influenza C virus is also called influenza C virus. Among these three types, influenza A virus is the most pathogenic, and the well-known HIN1...

Claims

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Application Information

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IPC IPC(8): A61K36/758A61P31/16A23L33/105
Inventor 徐缓苏红吕静岳宏新汪小婵
Owner LIAONING NORMAL UNIVERSITY
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