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Nasal cavity wetting agent containing trehalose

A technology of trehalose and nasal cavity, applied in the field of health care, can solve the problems of lack of promoting normal repair of nasal mucosa, inability to effectively inhibit and protect nasal mucosa, and large irritation of nasal mucosa, and achieve good moisturizing effect and good antibacterial effect. Effect, the effect of solving nasal dryness

Active Publication Date: 2016-03-09
QILU UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, how to solve the problems of insufficient wetting effect (short wetting time), inability to effectively inhibit bacteria and protect nasal mucosa, greater irritation to nasal mucosa, and lack of promotion of normal repair of nasal mucosa in conventional wetting methods when the nasal cavity is dry? It is a problem faced by those skilled in the art to provide a nasal wetting agent that can not only protect the nasal mucosa but also effectively moisturize and inhibit bacteria

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] (1) Put 2g of pharmaceutical grade sodium hyaluronate into 1L of deionized water, and stir with a magnetic stirrer for 2-5 minutes to completely dissolve the sodium hyaluronate to form a transparent viscous solution;

[0034] (2) Put 0.2g of pharmaceutical grade trehalose, 20ml of glycerin, and 0.01g of allantoin into the solution in (1) above, and stir with a magnetic stirrer for 3-5 minutes until all the trehalose is dissolved;

[0035] (3) Get 0.1g of superoxide dismutase (SOD), 0.8g of hexadiene-(2,4)-acid potassium (potassium sorbate), 1g of 10-hydroxyl-2-decenoic acid (royal jelly Acid, referred to as HAD) was added to the solution in (2), stirred with a magnetic stirrer for 5-10 minutes until the ingredients were mixed evenly, and the nasal cavity moisturizing composition was obtained;

[0036] (4) Put the prepared nasal cavity moisturizing composition into 20 transparent plastic bottles with a capacity of 50ml that have already been washed, then seal the plastic...

Embodiment 2

[0038](1) Put 2g of pharmaceutical grade sodium hyaluronate into 1L of deionized water, and stir with a magnetic stirrer for 2-5 minutes to completely dissolve the sodium hyaluronate to form a transparent viscous solution;

[0039] (2) Put 0.3g of pharmaceutical grade trehalose, 25ml of glycerin, and 0.02g of allantoin into the solution in (1), and stir with a magnetic stirrer for 3-5 minutes until all the trehalose is dissolved;

[0040] (3) Get 0.2g of superoxide dismutase (SOD), 0.8g of hexadiene-(2,4)-acid potassium (potassium sorbate), 1.5g of 10-hydroxyl-2-decenoic acid ( Add royal jelly acid, referred to as HAD) into the solution in (2), and stir with a magnetic stirrer for 5-10 minutes until the ingredients are evenly mixed to obtain a nasal cavity moisturizing composition;

[0041] (4) Put the prepared nasal cavity moisturizing composition into 20 transparent plastic bottles with a capacity of 50ml that have been washed already, then seal the plastic bottles, place th...

Embodiment 3

[0043] (1) Put 2g of pharmaceutical grade sodium hyaluronate into 1L of deionized water, and stir with a magnetic stirrer for 2-5 minutes to completely dissolve the sodium hyaluronate to form a transparent viscous solution;

[0044] (2) Put 0.2g of pharmaceutical grade trehalose, 20ml of glycerin, and 0.02g of allantoin into the solution in (1) above, and stir with a magnetic stirrer for 3-5 minutes until all the trehalose is dissolved;

[0045] (3) Get 0.2g of superoxide dismutase (SOD), 0.8g of hexadiene-(2,4)-acid potassium (potassium sorbate), 1g of 10-hydroxyl-2-decenoic acid (royal jelly Acid, referred to as HAD) was added to the solution in (2), stirred with a magnetic stirrer for 5-10 minutes until the ingredients were mixed evenly, and the nasal cavity moisturizing composition was obtained;

[0046] (4) Put the prepared nasal cavity moisturizing composition into 20 transparent plastic bottles with a capacity of 50ml that have been washed already, then seal the plastic...

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PUM

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Abstract

The invention discloses a nasal cavity wetting agent containing trehalose. The nasal cavity wetting agent is prepared by mixing 2-3 g of sodium hyaluronate, 0.2-0.5 g of the trehalose, 20-30 ml of glycerin, 0.01-0.02 g of allantoin, 0.1-0.2 g of SOD, 0.8-1 g of potassium sorbate, 1-1.5 g of royal jelly acid and 1 L of water. By serving as a man-made nasal cavity wetting agent, the nasal cavity wetting agent can keep the wetting function of the nasal cavity for a long time, prevent dust, tiny dust and bacterial microorganisms from invading the respiratory system, protect the nasal mucosae to the great extent, improve the condition that nasal mucus secretion is little and the nasal cavity is dry and effectively promote normal repair of the nasal mucosae.

Description

technical field [0001] The invention relates to the technical field of health care, in particular to a nasal cavity wetting agent containing trehalose. Background technique [0002] Modern factory exhaust emissions are increasing, automobile exhaust pollution is serious, and many factors have caused the air quality to decline day by day. The nose is the primary organ of the human respiratory system. It not only regulates the humidity and temperature of the air inhaled by the human body, but also filters harmful substances such as dust in the air. With the increase of air pollution, dust suspended in the air, toxic chemical particles, viruses, Bacteria, mould, allergens and other pathogenic factors have also increased significantly. [0003] The human nasal mucosa keeps the nasal cavity moist by secreting mucus. At the same time, the nasal mucus also contains lysozyme, which can inhibit and dissolve bacteria. Therefore, it can stick dust, dust, bacteria and other microorgani...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/44A61P11/02A61K31/728A61K31/7016A61K31/4166A61K31/201A61K31/047
CPCA61K31/047A61K31/201A61K31/4166A61K31/7016A61K31/728A61K38/44A61K2300/00
Inventor 王瑞明吉兴香
Owner QILU UNIV OF TECH
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