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Traditional Chinese medicine composition for treating and/or preventing oral diseases and preparing method thereof

A technology for oral diseases and compositions, which is applied in the field of traditional Chinese medicine compositions, can solve the problems of low local drug concentration, inconvenient use, and drug resistance, and achieve the effects of good solubility, health promotion, and alleviation of related symptoms

Active Publication Date: 2016-02-17
BEIJING TONGRENTANG MAIERHAI BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although basic periodontal treatment is effective in removing plaque and controlling inflammation, it is difficult to control plaque at an ideal level for a long time
Long-term use of antibiotics throughout the body may lead to adverse consequences such as bacterial imbalance and drug resistance, while the local concentration of the drug is relatively low
Although topical periodontal medication can avoid the possible adverse consequences of systemic medication, it also has disadvantages such as inconvenient use, multiple side effects, and drug resistance.
In addition, most of the various periodontal topical dosage forms at present are mainly antibacterial and bactericidal preparations, or some biofilm preparations can only promote the regeneration of gingival tissue

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] The preparation method of the notoginseng powder is as follows: take an appropriate amount of notoginseng, wash and dry, grind the notoginseng into fine powder with a superfine pulverizer, pass through a 200-mesh sieve, and set aside.

[0043] The preparation method of the salvia miltiorrhiza extract is as follows: take an appropriate amount of salvia miltiorrhiza, soak for 0.5-1.0h, heat and decoct at 90-100°C to extract twice, add 10-12 times the amount of water for the first time, extract for 1.0-1.5h, and extract for the second time Add 5-8 times the amount of water, extract for 0.5-1.0h, filter each time, combine the filtrates, concentrate the volume of the filtrates to 2-3 times the weight of Danshen g / ml, filter, and dry to obtain a powder for later use.

[0044] The preparation method of wild chrysanthemum extract is as follows: take an appropriate amount of wild chrysanthemum, soak for 0.5-1.0h, heat and decoct at 90-100°C for extraction twice, add 10-12 times t...

Embodiment 2

[0054] The preparation methods of Radix Notoginseng Powder, Salvia Miltiorrhiza Extract, and Wild Chrysanthemum Extract are the same as in Example 1.

[0055] In parts by weight, prepare the following components: 0.03 parts of Panax notoginseng powder, 0.08 parts of Danshen extract, 0.06 parts of wild chrysanthemum flower extract, 50 parts of sorbitol, 2.0 parts of polyethylene glycol-400, 25 parts of water, 0.3 parts of saccharin, 0.3 parts of sodium benzoate, 10 parts of glycerin, 0.5 parts of hydroxypropyl guar gum, 0.5 parts of wrinkled carrageen extract, 0.3 parts of cellulose gum, 20 parts of hydrated silica, 3.0 parts of sodium lauryl sulfate, 1.5 parts of titanium dioxide , essence 2.0 parts.

[0056] The preparation method of toothpaste is with embodiment 1.

Embodiment 3

[0058] The preparation methods of Radix Notoginseng Powder, Salvia Miltiorrhiza Extract, and Wild Chrysanthemum Extract are the same as in Example 1.

[0059] In parts by weight, prepare the following components: 0.05 parts of Panax notoginseng powder, 0.1 parts of Danshen extract, 0.08 parts of wild chrysanthemum flower extract, 45 parts of sorbitol, 1.5 parts of polyethylene glycol-400, 22 parts of water, 0.25 parts of saccharin, 0.25 parts of sodium benzoate, 7 parts of glycerin, 0.45 parts of hydroxypropyl guar gum, 0.4 parts of wrinkled carrageen extract, 0.25 parts of cellulose gum, 17 parts of hydrated silica, 2.5 parts of sodium lauryl sulfate, 1.2 parts of titanium dioxide , 1.5 parts of essence.

[0060] The preparation method of toothpaste is with embodiment 1.

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition for treating and / or preventing oral diseases. The traditional Chinese medicine composition is prepared from pseudo-ginseng powder, radix salviae milliorrhizae extract and wild chrysanthemum extract. The invention further provides toothpaste capable of treating and / or preventing gingivitis. The toothpaste contains the traditional Chinese medicine composition and auxiliary materials. The ointment is moderate in thickness, rich and fine in foam and high in solubility; due to the fact that natural plant extract is added, the toothpaste is mild, high in safety performance, remarkable in effect and capable of reducing the number of oral cavity germs and regulating the environment of the oil environment.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating and / or preventing oral diseases, in particular to a traditional Chinese medicine toothpaste for preventing and treating gingivitis and a preparation method thereof. Background technique [0002] Medically, the soft tissue that surrounds and covers the teeth is called gingiva, and the acute and chronic inflammation that occurs in gingival tissue is called gingivitis. Manifested as gum bleeding, redness, swelling, pain, continue to develop invasion of hard tissue, resulting in periodontitis, including inflammation of gum tissue and systemic diseases in the gums. [0003] The pathogenesis of most gingivitis cases is caused by local factors, mainly stimulated by plaque, calculus or food impaction on the neck of the teeth to cause gingival bleeding, edema to produce gingivitis, periodontitis. The endothelial tissue of the gingival sulcus is congested, and the inflammatory reac...

Claims

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Application Information

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IPC IPC(8): A61K36/537A61K8/97A61Q11/00A61P1/02
CPCA61K8/97A61K36/00A61K36/258A61K36/287A61K36/537A61K2800/34A61Q11/00A61K2300/00
Inventor 尹鹭王海平杜喜平
Owner BEIJING TONGRENTANG MAIERHAI BIOTECHNOLOGY CO LTD
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