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Ginseng leaf extractive manufacturing method and cosmetic composition comprising ginseng leaf extractive serving as effective ingredient

A manufacturing method and technology of ginseng leaves, applied in the direction of medical preparations containing active ingredients, cosmetics, drug combinations, etc., can solve the problems of wrinkles, decreased skin elasticity, etc., and achieve the improvement of skin fine lines, high extraction rate, excellent anti-aging The effect of the aging effect

Active Publication Date: 2016-01-27
HANKOOK COSMETICS MFG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the human body, the synthesis and decomposition of extracellular matrix such as collagen can be properly regulated, but with aging, its synthesis decreases and the expression of matrix metalloproteinase (MMP; Matrix Metalloprotease), which is the enzyme that decomposes collagen, is promoted, causing skin elasticity to decrease and wrinkles to form

Method used

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  • Ginseng leaf extractive manufacturing method and cosmetic composition comprising ginseng leaf extractive serving as effective ingredient
  • Ginseng leaf extractive manufacturing method and cosmetic composition comprising ginseng leaf extractive serving as effective ingredient
  • Ginseng leaf extractive manufacturing method and cosmetic composition comprising ginseng leaf extractive serving as effective ingredient

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Embodiment 1: the manufacture of sand-fried ginseng leaf extract

[0037] Mix 600 g of ginseng leaves that have been dried in the shade and remove impurities, and clean sea sand (SeaSand) with a similar volume ratio that can fully bury the ginseng leaves, and heat at 100-160°C while stirring. At this time, when the surface of the original yellow-green medicinal material turns brown, stop heating, cool at room temperature, and make sand-fried ginseng leaves. Shake off the sea sand, select only processed ginseng leaves, put in 10L alcohol ethanol as solvent, reflux extraction at 70°C for 3-6 hours, filter under reduced pressure, concentrate the filtrate under reduced pressure in a water tank at 40°C to obtain concentrated Ethanol sand fried ginseng leaf extract.

Embodiment 2

[0038] Embodiment 2: Manufacture of vinegar-baked ginseng leaf extract

[0039] After fully absorbing 600 g of ginseng leaves dried in the shade and removing impurities, an acetic acid aqueous solution containing 4 to 6% of acetic acid (acetic acid) having an acid ratio similar to vinegar, was heated at 100 to 160° C. while stirring. At this time, when the surface of the original yellow-green medicinal material turns brown, stop heating, cool at room temperature, and make vinegar to roast ginseng leaves. The manufactured processed product is put into 10L alcohol ethanol as a solvent, refluxed at 70°C for 3-6 hours, filtered under reduced pressure, and the filtrate is concentrated under reduced pressure in a water tank at 40°C to obtain concentrated ethanol-vinegar roasted ginseng leaf extract.

experiment example 1

[0044] [Experimental Example 1: Composition confirmation and content experiment of sand-fried ginseng leaf extract (Example 1) and vinegar-roasted ginseng leaf extract (Example 2)]

[0045] In order to confirm the main properties of the sand-fried ginseng leaf extract of Example 1, the vinegar-roasted ginseng leaf extract of Example 2, the ginseng leaf raw product extract and the ginseng leaf carbon extract obtained in Comparative Example 1 and Comparative Example 2 for comparison, Quantitative analysis of phenolic substances in the ingredients and changes in total phenolic content and ginsenoside content were performed as follows.

[0046] (1) Quantitative analysis of phenolic substances

[0047] Add 1-2 drops of 2.5% FeCl to the solution obtained by dissolving each extract in ethanol 3 Place it in the ethanol solution, and observe whether the color is dark green or a precipitate is formed.

[0048] (2) Analysis of total phenol content

[0049] 10 ml of distilled water was...

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Abstract

The invention relates to a ginseng leaf extractive manufacturing method and a cosmetic composition comprising the ginseng leaf extractive serving as an effective ingredient, and discloses a skin external cosmetic composition and a manufacturing method therefor. Compared with a conventional method which takes a pure ginseng leaf extractive as the ginseng leaf extractive of a conventional processed product, the method further improves the antioxidant effect and the activity inhibition and expression inhibition effect of matrix metalloproteinase through the ginseng leaf extractive (0.001-10.0% by weight) produced through a boiling-on-grain method or a method of stir-baking with vinegar. The composition can inhibit the activity of monophenyl oxidase and further improves the darkening skins or prevents the hyperpigmentation of the skin.

Description

technical field [0001] The invention relates to a method for processing and improving ginseng leaves (The Leaf of Panaxginseng) by processing traditional Chinese medicine and a cosmetic composition containing the improved ginseng leaf extract as the main active ingredient. Background technique [0002] The skin exposed to ultraviolet rays can cause skin cancer, phototoxicity, autoimmune disorders, photoallergies, skin aging, etc. due to the generation of free radicals and reactive oxygen species (ROS) (Norins, J.Invest.Dermatol., 39:445, 1962; Cadenas, Ann. Rev. Biochem., 58:79, 1989). In the human body, the synthesis and decomposition of extracellular matrix such as collagen can be properly regulated, but with aging, its synthesis decreases and the expression of matrix metalloproteinase (MMP; Matrix Metalloprotease), which is the enzyme that decomposes collagen, is promoted, causing skin elasticity to decrease and wrinkles to form . And this decomposing enzyme can also be...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K8/97A61P17/18A61Q19/08A61Q19/02
CPCA61K8/9789A61Q19/00
Inventor 崔钟玩郑珉硕朴昌珉林美辰金成根
Owner HANKOOK COSMETICS MFG
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