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Application of theacrine in preparation of nerve regeneration agent

A technology of nerve regeneration and tecanin, which is applied in food and health food. Tecanin can solve the problems of neuron damage, death, and reduce the level of nerve regeneration in the field of preparation of drugs that promote nerve regeneration.

Inactive Publication Date: 2015-10-14
何蓉蓉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, studies have also shown that the occurrence of neurological diseases may be related to the excessive release of excitatory glutamate, resulting in neuronal damage and death, reducing the level of nerve regeneration

Method used

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  • Application of theacrine in preparation of nerve regeneration agent
  • Application of theacrine in preparation of nerve regeneration agent
  • Application of theacrine in preparation of nerve regeneration agent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The preparation of Teacrine dripping pills: take 5.0g of the real compound Teacrine (Theacrine), mix well with 60009.5g of polyethylene glycol, melt at 80°C, cool in simethicone, drop into pills, Obtain 100 drop pills.

Embodiment 2

[0033] Preparation of Teacrine soft capsules: take 5.0 g of the real compound Theacrine (Theacrine), mix well with 45.0 g of vegetable oil, and send it into a soft capsule packaging machine to obtain 100 soft capsules.

Embodiment 3

[0035]Preparation of Teacrine Tablets: Take 5.0 g of the real compound Theacrine, add starch solution, granulate, compress into tablets, and subpackage to obtain 100 tablets.

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PUM

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Abstract

The invention discloses an application of a compound, theacrine, of which the structure is represented as the formula (I), in preparation of a nerve regeneration agent, and also discloses the nerve regeneration agent of which an active component is the theacrine represented as the structure formula (I). In the invention, it is fully proved that the compound theacrine and a drug, a beverage or food or a health-caring product containing the theacrine can effectively promote nerve regeneration and can provide applications of clinical prevention and treatment and improvement on nerve regeneration-related diseases comprising: Parkinson's disease, Alzheimer's disease, Down syndrome, cerebral vascular disorder, cerebral stroke, spinal cord injury, Huntington's disease, multiple sclerosis, amyotrophic lateralizing sclerosis, epilepsia, anxiety disorder, comprehensive disorder, depression and manic depression and the like.

Description

technical field [0001] The present invention relates to the use of a compound Theacrine, in particular to the application of Theacrine in the preparation of drugs for promoting nerve regeneration, food and health food. Background technique [0002] Traditionally, neurons in the adult central nervous system are non-regenerating, and nerve regeneration only occurs during embryonic and early postnatal periods. Recent studies have shown that new neurons can be generated in the hippocampus, subventricular zone and olfactory bulb of adult rodents and primates. Nerve regeneration continues throughout life. Under the stimulation of various pathological factors, neural stem cells (NSCs) proliferate, migrate, differentiate, and finally integrate into neuronal networks. In Parkinson's disease, Alzheimer's disease, Tang Syndrome, cerebrovascular disorder, stroke, spinal cord injury, Huntington's disease, multiple sclerosis, amyotrophic lateral sclerosis, epilepsy, anxiety disorder, com...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/522A61P25/00A61P25/28A61P25/14A61P25/16A61P25/08A61P25/22A61P25/24A61P25/18A23L1/30A23L2/52
Inventor 何蓉蓉李怡芳胡惠华栗原博
Owner 何蓉蓉
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