Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A quality detection method for Jieyu Shunxin Tablets

A quality inspection method and satisfactory technology, which can be used in measuring devices, instruments, scientific instruments, etc., can solve the problems of not meeting the production quality control, affecting the safety and effectiveness of traditional Chinese medicine preparations, and not being able to effectively control the quality of drugs, etc. The monitoring of the safety and effectiveness of traditional Chinese medicine, the method has good repeatability, and the quality is stable and safe.

Active Publication Date: 2016-08-24
NANJING HAICHANG CHINESE MEDICINE GRPCO LTD
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the lack of detection methods for this drug leads to the inability to effectively control the quality of the drug, which seriously affects the safety and effectiveness of traditional Chinese medicine preparations, and cannot meet the requirements of the society for the production quality control of modern Chinese medicine and the quality control of drug sales.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A quality detection method for Jieyu Shunxin Tablets
  • A quality detection method for Jieyu Shunxin Tablets
  • A quality detection method for Jieyu Shunxin Tablets

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] Such as figure 1 , 2 , One shown in 3, 4, 5, and 6 uses salvianolic acid B as a reference substance, and adopts thin-layer chromatography to identify whether Jieyu Shunxin tablets contain salvia miltiorrhiza; Laminar chromatography was used to identify whether Jieyu Shunxin Tablets contained Bupleurum components; the extract of Shichangpu reference medicinal material was used as the reference medicinal solution reference substance, and TLC was used to identify whether Jieyu Shunxin Tablets contained Shichangpu ingredients; TLC was used as the reference drug solution reference substance to identify whether Jieyu Shunxin Tablets contained polygala components; the turmeric control medicinal material extract was used as the reference drug solution reference substance to identify whether Jieyu Shunxin Tablets contained Polygala gold component; use berberine hydrochloride reference substance to identify whether there is Coptis chinensis in Jieyu Shunxin Tablets by thin-layer...

Embodiment 2

[0104] Take 5 tablets of Jieyu Shunxin Tablets, grind them finely, take about 0.5g, weigh them accurately, put them in a 50mL volumetric flask, add 20% ethanol, 40% ethanol, 60% ethanol, 80% ethanol, 100% ethanol, 20% ethanol Methanol, 40% methanol, 60% methanol, 80% methanol, and 100% methanol were each 50 mL, and the ultrasonic working frequency was 40KHz, and the power was 500W, and treated for 30 minutes. Take it out, let it cool, make up to volume with extraction solvent, shake well, and pass through 0.45μm Microporous membrane, filtration, sample injection analysis. see results Figure 7 .

[0105] The results showed that there were significant differences among the 10 extraction solvents, and the extraction rate of 80% methanol was higher, and the extraction with methanol was used as the test solution, the impurity peak was small, and the interference was small, so methanol was used as the extraction solvent of the test solution.

Embodiment 3

[0107] Take 5 pieces of Jieyu Shunxin Tablets, grind them finely, take about 0.5g, weigh them accurately, put them in a 50mL volumetric flask, add 50mL of 80% methanol accurately, and ultrasonically (working frequency 40KHz, power 500W) for 10min, 20min, 30min, respectively. After 40min, 50min, and 60min, take it out, let it cool, make up to volume with 80% methanol, shake well, pass through a 0.45μm microporous membrane, and inject the sample for analysis. see results Figure 8 .

[0108] The results showed that the extraction was basically complete in 40 minutes, so the extraction time was determined to be 40 minutes.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
recovery rateaaaaaaaaaa
Login to View More

Abstract

The invention discloses a method for detecting quality of a depression-relieving heart-comforting tablet and belongs to the field of care and traditional Chinese medicine detection. The method comprises the steps of respectively taking salvianolic acid B, saikoside a, saikoside d, acorus gramineus referenee crude herb extract, polygala tenuifolia referenee crude herb extract, curcuma aromatica referenee crude herb extract and berberine hydrochloride as reference substances, adopting the thin layer chromatography to identify whether the depression-relieving heart-comforting tablet contains salvia miltiorrhiza, Chinese thorowax root, acorus gramineus, polygala tenuifolia, curcuma aromatica and coptis chinensis; taking salvianolic acid B as a reference substance, and adopting the high-performance liquid chromatography to identify the content of salvianolic acid B in the depression-relieving heart-comforting tablet. The method is high in accuracy and can strictly control product quality, perform comprehensive and effective quality control on the depression-relieving heart-comforting tablet, monitor production process stability and guarantee quality uniformity, stability and reliability.

Description

technical field [0001] The invention relates to a detection method for traditional Chinese medicine preparations, in particular to a quality detection method for Jieyu Shunxin Tablets. Background technique [0002] The invention with the application number 201110405141.8 discloses a medicine for treating depression, Jieyu Shunxin Tablet, which is composed of Bupleurum, Salvia, Shichangpu, Polygala, Curcuma, Coptidis, keel, oyster, and green stone according to a certain proportion. The formula of Yushunxin Tablets includes Bupleurum 6g, Salvia 30g, Shichangpu 6g, Polygala 6g, Curcuma 10g, Coptidis 3g, keel 10g, oyster 10g, green stone 10g. In the formula, Salvia miltiorrhiza and Bupleurum chinensis are the monarch medicine. Bupleurum pungent acts bitterly, and is good at regulating the liver qi, soothes the liver and relieves depression, such as Bupleurum soothes the liver powder ("Jingyue Quanshu") and Xiaoyao powder ("Hejiju Prescription") , Danshen enters the Heart Meridi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N30/90
Inventor 蔡宝昌王彬秦昆明金俊杰陈丹妮张彦南郑艳萍王玉
Owner NANJING HAICHANG CHINESE MEDICINE GRPCO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com