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Traditional Chinese medicine compound capsules for treating atherosclerosis and preparation method thereof

A technology of atherosclerosis and capsules, which is applied in the field of traditional Chinese medicine, can solve the problems of restricting the application of drugs and patients' inability to insist on taking them, and achieve the effects of high bioavailability, easy carrying and taking, and increased stability

Inactive Publication Date: 2015-09-09
胡怀强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After the advent of statins, the elevated blood lipids have been well controlled, but because the disease requires a long period of intervention, the side effects caused by long-term use of statins have also aroused widespread concern in the medical community. In addition, the use of statins Higher prices also greatly limit the application of drugs in our country, resulting in many patients not being able to insist on taking them

Method used

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  • Traditional Chinese medicine compound capsules for treating atherosclerosis and preparation method thereof
  • Traditional Chinese medicine compound capsules for treating atherosclerosis and preparation method thereof
  • Traditional Chinese medicine compound capsules for treating atherosclerosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A traditional Chinese medicine compound capsule for treating atherosclerosis. The raw materials are composed of 120 parts by weight of lotus leaf, 120 parts of cassia, 120 parts of Gynostemma pentaphyllum, 60 parts of Liquor Rhubarb and 90 parts of Polygonum Cuspidatum.

[0031] The preparation steps are as follows:

[0032] (1) Preparation of extract powder

[0033] Weigh each raw material according to the prescription, and extract the extract powder separately, as follows:

[0034] Lotus leaf: extract twice with 75% ethanol of 20 times the volume of lotus leaf, soak for 2 hours each time, combine the extracts and filter, the filtrate is concentrated and vacuum dried to obtain lotus leaf extract powder;

[0035] Cassia seed: soak in 80% ethanol with 10 times volume of cassia seed for 1h, then reflux in 60℃ water bath for 2h, filter, collect the filtrate, add 6 times volume of 80% ethanol to the residue after filtration, and reflux at 60℃ water bath for 2h To 3000r·min -1 ...

Embodiment 2

[0044] A traditional Chinese medicine compound capsule for treating atherosclerosis. The raw materials are composed of 80 parts by weight of lotus leaf, 90 parts of cassia seed, 60 parts of Gynostemma pentaphyllum, 60 parts of Rhubarb and 60 parts of Polygonum cuspidatum.

[0045] The preparation steps are the same as in Example 1.

Embodiment 3

[0047] A traditional Chinese medicine compound capsule for treating atherosclerosis. The raw materials are composed of 150 parts by weight of lotus leaf, 150 parts of cassia seed, 150 parts of Gynostemma pentaphyllum, 90 parts of Liquor Rhubarb and 120 parts of Polygonum Cuspidatum.

[0048] The preparation steps are the same as in Example 1.

[0049] The Chinese medicine compound capsule for treating atherosclerosis and the atorvastatin calcium tablet of the present invention were simultaneously subjected to animal experiments to prove their medicinal effects. The method and results are as follows:

[0050] 1. Experimental materials

[0051] (1) Experimental animals

[0052] 48 adult SPF male Wistar rats, weighing 250-300g, provided by the Laboratory Animal Center of Shandong University, laboratory animal production license number: SCXK (Lu) 20090001 (issued by Shandong Science and Technology Department), laboratory animal quality certificate number: Lu Dongzheng No. 1205215...

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Abstract

The invention provides traditional Chinese medicine compound capsules for treating atherosclerosis and a preparation method thereof. The traditional Chinese medicine compound capsules consist of the following raw material medicines in parts by weight: 80-150 parts of lotus leaves, 90-150 parts of cassia seeds, 60-150 parts of gynostemma pentaphyllum, 60-90 parts of wine-treated Chinese rhubarb and 60-120 parts of giant knotweed rhizome. The traditional Chinese medicine compound capsules provided by the invention have the effects of purifying and removing turbid blood, can be used for regulating blood lipid and relatively well inhibiting the occurrence and development of atherosclerosis, are convenient to take and low in cost, and also cannot cause significant toxic or side effects.

Description

Technical field [0001] The invention belongs to the field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine compound capsule for treating atherosclerosis and a preparation method. Background technique [0002] With the continuous improvement of the socio-economic level, people’s dietary structure and lifestyle have undergone great changes, coupled with the increasingly serious aging problem, atherosclerosis has increasingly become an important pathogenic factor that endangers human health and promotes the heart The occurrence of cerebrovascular diseases, especially the important pathological basis of arteriosclerotic cerebral infarction, greatly affects the quality of life of patients, and also brings severe social problems. It is one of the urgent research topics in the medical field. [0003] In recent years, the causes and pathogenesis of atherosclerosis have been further understood, and in-depth research has been conducted on the d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61K9/48A61P9/10
Inventor 胡怀强范玉芹
Owner 胡怀强
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