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Traditional Chinese medicine preparation for treating sjogren syndrome

A technology for Sjögren's syndrome and traditional Chinese medicine preparations, applied in the field of medicine, can solve the problems of small toxic and side effects, many target points, inconvenient taking, etc., and achieve the effects of strong patient tolerance, obvious clinical efficacy, and convenient taking.

Inactive Publication Date: 2015-09-02
QINGDAO CHENDA BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine treatment is mainly based on syndrome differentiation. Traditional Chinese medicine has accumulated rich historical experience in the treatment of "dryness syndrome". There are problems of slow onset, poor taste, and inconvenient taking. Therefore, it is necessary to develop more high-quality Chinese medicine preparations for treating Sjögren’s syndrome by combining modern Chinese medicine theory, using advanced production technology and research methods.

Method used

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  • Traditional Chinese medicine preparation for treating sjogren syndrome
  • Traditional Chinese medicine preparation for treating sjogren syndrome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1 Tablet

[0028] Weigh the raw materials of the present invention according to the following parts by weight: 15 parts of Rehmannia glutinosa, 13 parts of dogwood, 11 parts of Poria, 7 parts of cardamom, 5 parts of Asarum, 11 parts of silkworm, 11 parts of licorice, 9 parts of Nansha ginseng, Radix Scrophulariaceae 8 servings, 10 servings of Panax notoginseng.

[0029] The preparation process is as follows:

[0030] Weigh the above traditional Chinese medicine components according to the aforementioned weights and pulverize them into coarse powder respectively; add water 6 times the total weight of the medicinal materials, soak for 1.5 hours, decocting for 3 hours, and decoct 2 times; combine the decocting liquid and filter; the filtrate The extract with a relative density of 1.15-1.20 when concentrated to 55° C. is dried, pulverized into fine powder, and passed through a 150-mesh sieve; 1% magnesium stearate is added and mixed to obtain slow-release layer gra...

Embodiment 2

[0032] Example 2 Capsules

[0033] Weigh the raw materials of the present invention according to the following parts by weight: 15 parts of Rehmannia glutinosa, 13 parts of dogwood, 11 parts of Poria, 7 parts of cardamom, 5 parts of Asarum, 11 parts of silkworm, 11 parts of licorice, 9 parts of Nansha ginseng, Radix Scrophulariaceae 8 servings, 10 servings of Panax notoginseng.

[0034] The preparation process is as follows:

[0035] Weigh the above traditional Chinese medicine components according to the aforementioned weights and pulverize them into coarse powder respectively; add water 6 times the total weight of the medicinal materials, soak for 1.5 hours, decocting for 3 hours, and decoct 2 times; combine the decocting liquid and filter; the filtrate The extract with a relative density of 1.15-1.20 when concentrated to 55°C, dried, pulverized into fine powder, and passed through a 150-mesh sieve; use 50% ethanol as a wetting agent, stir the mixture into a soft material, ...

Embodiment 3

[0037] Example 3 Granules

[0038] Weigh the raw materials of the present invention according to the following parts by weight: 15 parts of Rehmannia glutinosa, 13 parts of dogwood, 11 parts of Poria, 7 parts of cardamom, 5 parts of Asarum, 11 parts of silkworm, 11 parts of licorice, 9 parts of Nansha ginseng, Radix Scrophulariaceae 8 servings, 10 servings of Panax notoginseng.

[0039] The preparation process is as follows:

[0040] Weigh the above traditional Chinese medicine components according to the aforementioned weights and pulverize them into coarse powder respectively; add water 6 times the total weight of the medicinal materials, soak for 1.5 hours, decocting for 3 hours, and decoct 2 times; combine the decocting liquid and filter; the filtrate The extract with a relative density of 1.15-1.20 when concentrated to 55℃, dried, pulverized into fine powder, passed through a 150-mesh sieve; added an appropriate amount of mannitol and other auxiliary materials to make so...

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine preparation for treating sjogren syndrome and a preparation method thereof. The traditional Chinese medicine preparation is prepared by the following medicines of prepared rhizome of rehmannia, dogwood, tuckahoe, cardamun, asarum, stiff silkworm, licorice root, ladybell root, radix scrophulariae, and flower of notoginseng. The traditional Chinese medicine preparation has the advantages that the compounding is reasonable, the preparation is easy, the obvious therapy effects of warming and reinforcing livers and kidneys, moistening dryness and eliminating dampness, and invigorating qi and nourishing yin are realized, and the traditional Chinese medicine preparation is an effective medicine for treating the sjogren syndrome, especially the yin deficiency and endogenous dryness type sjogren syndrome.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine preparation for treating Sjogren's syndrome. Background technique [0002] Sjögren's syndrome is an autoimmune chronic inflammatory disease of the exocrine glands, the main symptoms of which are dryness of the mouth and eyes, joint pain, and swelling and decreased secretion of the salivary or lacrimal glands, forming keratoconjunctivitis sicca and Dry mouth. At the same time, it can involve the liver, kidney, gastrointestinal tract, lymph and other organs and tissues, resulting in a variety of clinical manifestations. The disease mostly occurs in women aged 40-60 years. It is often covered up by other symptoms in the early stage of the disease, which is easy to cause missed diagnosis and misdiagnosis. It can exist alone, called primary Sjogren's syndrome, or it can be secondary to other autoimmune diseases, said For secondary Sjögren'...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P37/02A61K35/64
Inventor 不公告发明人
Owner QINGDAO CHENDA BIOLOGICAL SCI & TECH
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