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A kind of multi-dimensional element dispersible tablet

A technology of multi-dimensional elements and dispersible tablets, which is applied in the direction of inorganic active ingredients, organic active ingredients, iodine compound active ingredients, etc. It can solve the problems of multi-dimensional element tablets with many main ingredients, unstable main drugs, and great difficulty, and achieve fast disintegration , Coordinating the effects of enhancing immunity and improving product quality

Active Publication Date: 2017-07-14
ZHEJIANG SHENGBOKANG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to the large number of main ingredients in multidimensional element tablets, some of the main ingredients are unstable under hot and humid conditions, so it is difficult to prepare tablets with rapid and stable release.

Method used

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  • A kind of multi-dimensional element dispersible tablet
  • A kind of multi-dimensional element dispersible tablet
  • A kind of multi-dimensional element dispersible tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Select the WP50N / 75 roller press manufactured by Alexander Company in Germany;

[0034] The water-soluble chitosan in this example is purchased from Guangzhou Shengtong Trading Co., Ltd., or can be prepared by itself according to the existing technology. The molecular weight of the chitosan is 1300-1600.

[0035] A preparation method of multidimensional element dispersible tablet:

[0036] The following raw materials were prepared into 1000 pieces;

[0037]

[0038]

[0039]Preparation of granules: Divide the above raw materials into A, B, and C materials, pre-mix A, B, and C materials respectively, and then use a dry granulation machine to obtain granules, then add magnesium stearate to the A, B, and C granules, and polymerize Povidone K30 6g and crospovidone are mixed evenly and granulated;

[0040] The A material is: vitamin A acetate powder, vitamin E powder, vitamin D3, vitamin B2, vitamin B12, vitamin B1, vitamin B6, magnesium oxide, potassium sulfate, man...

Embodiment 2

[0047] Select the WP50N / 75 roller press manufactured by Alexander Company in Germany;

[0048] The water-soluble chitosan in this example is purchased from Guangzhou Shengtong Trading Co., Ltd., or can be prepared by itself according to the existing technology. The molecular weight of the chitosan is 1300-1600.

[0049] A preparation method of multidimensional element dispersible tablet:

[0050] The following raw materials were prepared into 1000 pieces;

[0051]

[0052]

[0053]

[0054] Preparation of granules: Divide the above raw materials into A, B, and C materials, pre-mix A, B, and C materials respectively, and then use a dry granulation machine to obtain granules, then add magnesium stearate to the A, B, and C granules, and polymerize Mix 7.25g of vitamin K30 and crospovidone evenly to make granules;

[0055] The A material is: vitamin A acetate powder, vitamin E powder, vitamin D3, vitamin B2, vitamin B12, vitamin B1, vitamin B6, magnesium oxide, potassiu...

Embodiment 3

[0062] Select the WP50N / 75 roller press manufactured by Alexander Company in Germany;

[0063] The water-soluble chitosan in this example is purchased from Guangzhou Shengtong Trading Co., Ltd., or can be prepared by itself according to the existing technology. The molecular weight of the chitosan is 1300-1600.

[0064] A preparation method of multidimensional element dispersible tablet:

[0065] The following raw materials were prepared into 1000 pieces;

[0066]

[0067]

[0068] Preparation of granules: Divide the above raw materials into A, B, and C materials, pre-mix A, B, and C materials respectively, and then use a dry granulation machine to obtain granules, then add magnesium stearate to the A, B, and C granules, and polymerize Povidone K30 5g and crospovidone were mixed evenly and granulated;

[0069] The A material is: vitamin A acetate powder, vitamin E powder, vitamin D3, vitamin B2, vitamin B12, vitamin B1, vitamin B6, magnesium oxide, potassium sulfate, m...

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Abstract

The invention discloses a multi-dimensional element dispersible tablet. The invention screens out the optimal dosage of auxiliary materials through redesigning the prescription, adopts advanced dry granulation, tablet pressing, and film-coated tablet production technology, and keeps the content of various vitamins unchanged. It has become an advanced dispersible tablet dosage form in China. Compared with ordinary tablets: it is easier to dissolve in the body, release the drug and be absorbed by the human body; increase the uniformity of dispersion, and the product can be dissolved within 3 minutes and pass through the No. 2 sieve; and adopts high-efficiency The dissolution rate of vitamin B1, vitamin B2, nicotinamide and other vitamins in each tablet is accurately measured by liquid chromatography, which is more than 98% of the labeled amount, while ordinary tablets only qualitatively detect that the disintegration time limit is less than 30 minutes, and the product quality is significantly improved. And in the treatment of gastrointestinal cancer, it can relieve symptoms and enhance the body's immunity.

Description

technical field [0001] The invention belongs to the technical field of health care medicines, and in particular relates to a multidimensional element dispersible tablet and a preparation method thereof. Background technique [0002] With the improvement of people's living standards and awareness of health care, as well as changes in people's eating habits and dietary structure, such as excessive intake of fat and refined sugar, insufficient intake of vegetables and fruits, and unbalanced meals, etc. lead to people's intake of A certain nutrient deficiency. A considerable number of people are used to taking some nutritional supplements every day. Nutrient supplements are products made from one or several chemically synthesized or extracted nutrients from natural animals and plants for the purpose of supplementing the nutrients needed by the human body. Multi-element nutritional supplements with the main purpose of supplementing vitamins and trace elements are important vari...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/36A61K31/722A61K31/714A61K31/593A61K31/525A61K31/51A61K31/455A61K31/4415A61K31/375A61K31/047A61K31/198A61K31/355A61K31/222A61K33/08A61K33/32A61K33/04A61K33/30A61K33/18A61K33/34A61K31/197A61K31/194A61K31/205
Inventor 张晓明张聪沈泽龙
Owner ZHEJIANG SHENGBOKANG PHARMA CO LTD
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