Universal sampler, gas chromatograph and hyphenated spectrometer

Abstract

A general-purpose injector is disclosed, comprising: an injection port mechanism, an injector housing, a vaporization chamber, a heater, a temperature control unit, a carrier gas channel, a septum purging channel, a split flow channel, and a coolant channel , multi-channel air flow control valve, and temperature control unit. This general-purpose injector is equivalent to a temperature-programmed injector that combines split / splitless and cool-on-column injection. It fully utilizes the strengths of various injection methods, overcomes multiple shortcomings, and is more practical. , better flexibility.

Description

technical field [0001] The invention belongs to the field of analysis and detection, and relates to a sample injection device for a gas chromatography or a gas chromatography-ion mobility spectrometer, in particular to a split / splitless programmed temperature rise sample injector for capillary columns. Background technique [0002] During the analysis of samples by gas chromatography (GC), GC and ion mobility spectrometry (IMS) / mass spectrometry (MS), the sample first passes through the injector. The sample injector is used to gasify the sample components of interest at the first position and mix them with the carrier gas to quickly, accurately and quantitatively add them to the GC column head. Since Perkin Elmer produced the first capillary column, due to its advantages of high column efficiency and good separation performance, more than 90% of GC analysis is realized by capillary column today (“BasicGas Chromatography”, Second Edition, by Harold M . McNair and James M. Mi...

AI Technical Summary

Problems solved by technology

[0005] One is that the heating temperature of the vaporization chamber is not uniform. In some cases, the temperature difference between the center and both ends of the vaporization chamber is large, which causes uneven vaporization of the sample or components with different boiling points vaporize to reach a temperature lower than the vaporization temperature. condensation

[0006] The second is that the carrier gas has not been preheated, and the carrier gas will have a temperature gradient change when entering the gasification chamber, which will cause different gasification speeds of different components of the sample.

This patent reduces the problem of uneven vaporization of the sample, however the injector is only available in splitless mode

Due to the complex operating conditions of the splitless injection mode and high requirements for operating technology, the application in actual work is far less common than that of split injection. Only when split injection cannot meet the analysis requirements (mainly sensitivity requirements) is considered splitless Sample

[0010] In addition, when continuous sampling is required when there are many detection tasks, and the boiling range of two adjacent samples is significantly different, the temperature of the injector needs to be reset, although different types of split / splitless injectors There are many, but there are not many general-purpose injectors with rapid cooling

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