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Medicine for treating Qi-stagnation and blood stasis type coronary heart disease and preparation method thereof

A technology for qi stagnation and blood stasis type, coronary heart disease, applied in the direction of drug combination, medical formula, cardiovascular system diseases, etc., can solve the problems of unsatisfactory treatment effect, side effects of patients, high cost, etc., to achieve non-toxic side effects, low price Low, fast onset effect

Inactive Publication Date: 2015-06-10
付连进
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] However, the therapeutic effect of Western medicine is not very satisfactory, and the cost is expensive, which will cause side effects to patients, easy to relapse, and easy to produce drug dependence.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0070] Wherein, when the dosage form of the medicine is a tablet, its preparation method comprises the following steps:

[0071] The first step is to mix the raw materials of the drug in proportion, add ethanol with an alcohol concentration of 85% to 95% relative to the mass of the mixture, heat and reflux for 4 to 6 hours, extract, and filter to obtain the first extraction liquid; the medicinal dregs obtained by filtering are then added with ethanol with an alcohol concentration of 90% to 95% relative to the quality of the medicinal dregs 2 to 4 times, heated and refluxed for 1 to 3 hours, extracted, and filtered to obtain a second extract; The first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0072] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 3 hours, pulverized, and sieved to obtain an ultrafine powder of 400 m...

Embodiment 1

[0084] Example 1 tablet

[0085] The preparation process of the tablet of the present invention is: get 150g of Evodia rutaecarpa, 200g of Fructus aurantii, 320g of Salvia miltiorrhiza, 180g of domino fern, 350g of safflower, 300g of delphinium sacrum, 220g of platycodon, 200g of lovage, 200g of longum longum, 150g of Alkaline Sage, 250g of agarwood, 320g of melon wood, 300g of white peony, 340g of turmeric, 160g of turmeric, 280g of angelica, 350g of wulingzhi, 330g of azulene, 220g of Cyperus cyperi, 240g of tortoise shell, 320g of tribulus terrestris, 200g of tribulus terrestris, and wind-dispelling 350g, 240g of apocynum leaves, 200g of Fushen, 340g of calamus, 150g of radish, 220g of scallion, 300g of sage, 200g of flavescens, 250g of silkworm, 300g of jujube, 160g of sea cucumber and 250g of weed seeds;

[0086] The first step is to mix the various raw materials of the medicine in proportion, add ethanol with an alcohol concentration of 95% that is 5 times the mass of th...

Embodiment 2

[0089] Embodiment 2 oral liquid

[0090] The preparation process of the oral liquid of the present invention is: get 220g of Evodia rutaecarpa, 250g of Fructus aurantii, 340g of Salvia miltiorrhiza, 200g of domino fern, 350g of safflower, 300g of delphinium sacrum, 310g of platycodon, 140g of lovage, 230g of longan longan, 200g of Alkaline Sage, 150g of agarwood, 350g of melon wood, 240g of white peony, 330g of turmeric, 160g of turmeric, 300g of angelica, 340g of wulingzhi, 320g of azulene, 220g of Cyperus cyperi, 240g of tortoise shell, 350g of tribulus terrestris, 200g of tribulus terrestris, and wind-dispelling 330g, 250g of apocynum leaves, 200g of Fushen, 340g of calamus, 220g of radish, 250g of scallion, 300g of sage, 210g of flavescens, 220g of silkworm, 300g of jujube, 150g of sea cucumber and 260g of weed seeds;

[0091] The first step is to mix the delphinium, platycodon, solitary, longum, alkali iris, agarwood, melon wood, white peony, dung, turmeric, angelica, wul...

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Abstract

The invention discloses a medicine for treating a Qi-stagnation and blood stasis type coronary heart disease and preparation method thereof. The medicine comprises various raw material medicinal materials: fructus evodiae, fructus aurantii, salvia miltiorrhiza, lepidogrammitis rostrata, safflower carthamus, delphinium brunnonianum royle, platycodon grandiflorum, radix angelicae tuhuo, fructus piperis longi, iris halophila pall., agilawood, fissistigma oldhamii, radix paeoniae alba, stephania longa, agilawood, carcuma longa, angelica, trogopterus dung, bryoniifolia, rhizoma cyperi, tortoise shell, trigone, tribulus terrestris, zanthoxylum rhetsoides, folium apocyni veneti, fushen, rhizoma acori graminei, raphanus sativus l., allium macrostemon, lyonia, radix sophorae flavescentis, bombyx batryticatus, fructus ziziphi jujubae, morina chinensis and root of montane baliospermum. The medicine provided by the invention has the effects of promoting blood circulation to remove blood stasis, is mainly used for treating the Qi-stagnation and blood stasis type coronary heart disease, and has the advantages of being fast to take effect, high in effective rate, definite in curative effect, short in treatment course, low in price, and is free from toxic and side effects.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating coronary heart disease of Qi stagnation and blood stasis type and a preparation method thereof. Background technique [0002] Coronary heart disease, that is, coronary atherosclerotic heart disease is a heart disease caused by atherosclerotic lesions in the coronary arteries that cause stenosis or blockage of the vessel lumen, resulting in myocardial ischemia, hypoxia or necrosis. "Coronary Heart Disease". However, the scope of coronary heart disease may be wider, including inflammation, embolism, etc. leading to stenosis or occlusion of the lumen. [0003] Risk factors for coronary heart disease: including modifiable risk factors and non-modifiable risk factors. Modifiable risk factors are: hypertension, dyslipidemia (high total or low-density lipoprotein cholesterol, high triglycerides, low high-density lipoprotein cholesterol), o...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P9/10A61K35/24A61K35/586A61K35/64
Inventor 付连进石洪柱张宁
Owner 付连进
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