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Application of meadowrue-corydalis-root traditional Chinese medicine composition to prepare medicaments treating heart disease

A composition, the technology of Rhizoma Coptidis, is applied in a new application field in the preparation of drugs for treating heart disease, and achieves the effects of outstanding substantive characteristics, no toxic side effects, and improvement of clinical symptoms and indicators.

Inactive Publication Date: 2015-05-06
GUANGXI JINCHUANGUCAO BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no literature record about the use of Litectin as a drug for heart disease

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] (1) Take 800g of Litectin chinensis, crush it into a coarse powder, extract it by percolation with 4800g of ethanol with a volume ratio concentration of 50%, store the extraction solution for later use, add 2400g of water to the dregs, decoct for 10 minutes, and filter. Combine with percolation liquid, recover ethanol, concentrate to 2400g, filter, and stand for 1 day to obtain solution A;

[0039] (2) Take 10g of musk, crush it, distill it twice, add 920g of water each time, collect 600g of distillate each time, combine the distillates to obtain solution B;

[0040] (3) Combine solution A and solution B to obtain the active ingredient of the present invention.

Embodiment 2

[0042] (1) Take 1500g of Litectin chinensis, crush it into coarse powder, extract it by percolation with 16800g of ethanol with a volume ratio concentration of 80%, store the extraction solution for later use, add 6300g of water to the dregs, decoct for 30 minutes, filter, Combine with percolation liquid, recover ethanol, concentrate to 6300g, filter, stand for 2 days to obtain solution A;

[0043] (2) Take 50g of musk, crush it, distill it twice, add 6000g of water each time, collect 4500g of distillate each time, combine the distillates to obtain solution B;

[0044] (3) Combine solution A and solution B to obtain the active ingredient of the present invention;

[0045] (4) Combine solution A and solution B, add 0.5% Tween 80, mix evenly, adjust the pH to 8.5, filter, fill, and sterilize to obtain the injection of the present invention.

Embodiment 3

[0047] (1) Take 1200g of Litectin chinensis, Nine-headed Lion Grass, and Chrysanthemum chrysanthemum, grind them into coarse powder, extract with 8,500g of ethanol with a volume ratio concentration of 60%, store the extraction solution for later use, and add 5,100g of dregs water, decocted for 20 minutes, filtered, combined with the percolate, recovered ethanol, concentrated to 3400g, filtered, and stood for 3 days to obtain solution A;

[0048] (2) Take 40g of musk, pulverize, distill twice, add 4000g of water each time, collect 3600g of distillate each time, combine the distillates to obtain solution B;

[0049] (3) Combine solution A and solution B to obtain the active ingredient of the present invention;

[0050] (4) After the active ingredient is concentrated to an appropriate relative density, it is mixed with an appropriate amount of starch and dextrin, granulated, dried, and pressed into tablets to obtain the tablet of the present invention.

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PUM

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Abstract

The invention discloses application of a meadowrue-corydalis-root traditional Chinese medicine composition to prepare medicaments treating heart disease, that is, the invention discloses a new purpose of a traditional Chinese medicine composition employing meadowrue corydalis root and moschus as raw materials to prepare medicaments treating and / or preventing heart disease.

Description

technical field [0001] The present invention relates to a new application of the Chinese medicine composition of Yanhuanglian, that is, a new application in the preparation of medicines for treating heart diseases. Background technique [0002] Heart disease is a relatively common circulatory system disease. The circulatory system is composed of the heart, blood vessels, and neurohumoral tissues that regulate blood circulation. Circulatory system diseases are also called cardiovascular diseases, including diseases of all the above-mentioned tissues and organs. They are common diseases in internal medicine, among which heart disease is the most common. Can significantly affect patient labor. The causes of heart disease are quite complicated. For example, long-term repeated negative emotions play an important role in the occurrence of heart disease. In addition, bad eating habits such as drinking a lot of alcohol or coffee, overeating, excessive sex life, smoking or passive ...

Claims

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Application Information

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IPC IPC(8): A61K36/66A61P9/00A61K35/55
Inventor 黄荣黄宣霖
Owner GUANGXI JINCHUANGUCAO BIOLOGICAL SCI & TECH
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