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Traditional Chinese medicine composition for loosening the bowel to relieve constipation and preparation method thereof

A technology of laxative and laxative composition, which is applied in the field of medicine and health, can solve the problems of short effective time, unsuitable for long-term use of laxatives, and inability to carry out consolidation treatment, etc., and achieve the goal of increasing the number of defecation grains, normal stool properties, and low production cost Effect

Active Publication Date: 2015-04-29
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The above treatment methods are effective for a short time and cannot be consolidated.
However, most patients with constipation have relatively weak constitutions, so it is not advisable to take laxatives for a long time.

Method used

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  • Traditional Chinese medicine composition for loosening the bowel to relieve constipation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Take Shayuanzi 13g, Torreya 10g, Rhizoma Drynariae 6g, Mori 13g, Scallion 10g, Rose thorn fruit 9g. Take all the medicinal materials, add water and extract 3 times, the amount of water added each time is equivalent to 15 times, 10 times, and 6 times the total weight of the medicinal materials, and the extraction time is 3 hours, 2 hours, and 1 hour respectively. Combine the extracts and filter , when the filtrate is concentrated to 60 °C, the relative density is 1.20 extract, add auxiliary materials starch, microcrystalline cellulose, gelatin, sodium carboxymethyl starch, magnesium stearate, micropowder silica gel, sucrose, mix well, make soft material, make Granules, compressed into tablets.

Embodiment 2

[0058] Take Shayuanzi 90g, Torreya 9g, Rhizoma Drynariae 3g, Mori 9g, Scallion 5g, and Rose thorn fruit 6g. Take all the medicinal materials, add water to extract 4 times, the amount of water added each time is equivalent to 6 times the total weight of the medicinal materials, and the extraction time is 1 hour each time, combine the extracts, filter, and concentrate the filtrate to an extract with a relative density of 1.05 at 80°C , add ethanol to make the alcohol content 40%, let it stand for 6 hours, filter, the filtrate is concentrated into liquid extract, dried into dry paste powder, crushed through a 120 mesh sieve, added auxiliary materials starch, sucrose powder, talcum powder, hard Magnesium fatty acid to prepare granules.

Embodiment 3

[0060] Take Shayuanzi 15g, Torreya chinensis 15g, Drynaria fortunei 9g, Mori 15g, Allium scallion 10g, Rose thorn fruit 10g. Take all the medicinal materials, add water and extract 3 times, the amount of water added each time is equivalent to 10 times the total weight of the medicinal materials, and the extraction time is 3 hours each time, combine the extracts, filter, and concentrate the filtrate to an extract with a relative density of 1.20 at 60°C , add ethanol to make the alcohol content 80%, let it stand for 24 hours, filter, the filtrate is concentrated into liquid extract, dried into dry paste powder, crushed through a 120 mesh sieve, and added appropriate amount of starch, microcrystalline cellulose, gelatin , sodium carboxymethyl starch, magnesium stearate, micropowder silica gel, sucrose, mixed evenly, made soft material, granulated, compressed into tablets to obtain.

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Abstract

The invention discloses health food for loosening the bowel to relieve constipation and a preparation method thereof. The health food is prepared from flatstem milkvetch seed, Chinese torreya seed, drynaria rhizome, mulberry twigs, bulb of long stamen onion and rosa maximowicziana regel which serve as raw materials. Animal pharmacodynamic experimental results show that the motion rate of a small intestine of a mouse taking the health food is obviously improved in small intestine motion experiments, and compared with a model contrast group, a significant difference exists. In determination experiments of defecation time, fecal grain number and fecal weight, the time of the mouse for beginning defecating dark stool is obviously shortened, the fecal weight is obviously increased, the fecal grain number is obviously increased, and compared with the model contrast group, a significant difference exists. The health food has the effect of loosening the bowel to relieve constipation.

Description

technical field [0001] The invention relates to the field of medicine and hygiene, in particular to a traditional Chinese medicine composition for relaxing bowels and a preparation method thereof. Background technique [0002] Constipation is a common condition, usually refers to infrequent stools, hard texture, difficult defecation (or poor defecation). Chronic constipation is a common clinical disease, and the incidence rate in western countries is about 2% to 27%. Laxatives cost about $400 million a year in the United States. The survey in Beijing area of ​​my country shows that the incidence rate of chronic constipation is 6.07%, and the incidence rate of constipation in the elderly over 60 years old is as high as 11.5%. Chronic constipation has become a social problem, seriously affecting the quality of life of patients. [0003] Constipation can be divided into organic and functional two types from the etiology. Organic diseases include intestinal organic lesions, ...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P1/10
Inventor 杨北妮陈明郑志远卢敏玲
Owner GUANGXI WUZHOU PHARMA GRP
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