External traditional Chinese medicine composition with efficacies of scavenging free radical and removing redness and swelling as well as preparation and preparation method of external traditional Chinese medicine composition
A technology of free radicals and compositions, applied in the field of external use of traditional Chinese medicine compositions, can solve the problems of little research on damage, and achieve the effects of simple preparation method, easy acceptance, inhibition and reduction of capillary permeability
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Embodiment 1
[0055] The preparation of embodiment 1 this Chinese medicine composition
[0056] (1) Pass through a 40-mesh sieve after the following raw materials are pulverized, weigh and mix according to the weight ratio;
[0057] Agarwood 20g, honeysuckle 10g, Chuanqiong 10g, wild chrysanthemum 10g, amber 5g.
[0058] (2) Soak the bulk drug in 70% ethanol at room temperature for 2 hours, the mass volume ratio of the bulk drug to ethanol g / ml is 1:15; ultrasonically extract at 50°C for 50 minutes with frequency 50kHz, power 160W;
[0059] (3) filtering the extract obtained in step (2) through a 100 mesh filter plate to obtain the filtrate;
[0060] (4) Concentrate the filtrate to 20% of the original volume to obtain a concentrate; add 1,3-butanediol to the concentrate, stir and dissolve at 50°C for 1 hour, and the mass ratio of the concentrate to 1,3-butanediol is 1 : 1; sterilized at 90°C for 20 minutes after filtering with a filter plate, to obtain.
Embodiment 2
[0061] The preparation of embodiment 2 this Chinese medicine composition
[0062] (1) Pass through a 40-mesh sieve after the following raw materials are pulverized, weigh and mix according to the weight ratio;
[0063] Agarwood 18g, honeysuckle 8g, Chuanqiong 12g, wild chrysanthemum 12g, amber 3g.
[0064] (2) Soak the crude drug in 60% ethanol at room temperature for 4 hours, the mass volume ratio of the crude drug to ethanol g / ml is 1:18; use ultrasonic wave with a frequency of 40 kHz and a power of 100 W for 40 minutes at 40°C;
[0065] (3) 200 meshes of the extract obtained in step (2) are filtered, and the filter plate is finely filtered to obtain the filtrate;
[0066] (4) Concentrate the filtrate to 30% of the original volume to obtain a concentrated solution; add 1,3-butanediol to the concentrated solution, stir and dissolve at 50°C for 1 hour, and the mass ratio of the concentrated solution to 1,3-butanediol is 1 : 2; sterilized at 85° C. for 30 minutes after filter...
Embodiment 3
[0067] Embodiment 3 The preparation of this Chinese medicine composition
[0068] (1) Pass through a 40-mesh sieve after the following raw materials are pulverized, weigh and mix according to the weight ratio;
[0069] Agarwood 24g, honeysuckle 12g, Chuanqiong 8g, wild chrysanthemum 8g, amber 8g.
[0070] (2) Soak the crude drug in 80% ethanol at room temperature for 3 hours, the mass volume ratio of the crude drug to ethanol g / ml is 1:12; use ultrasonic waves with a frequency of 30 kHz and a power of 120 W for 45 minutes at 60°C;
[0071] (3) 200 meshes of the extract obtained in step (2) are filtered, and the filter plate is finely filtered to obtain the filtrate;
[0072] (4) Concentrate the filtrate to 25% of the original volume to obtain a concentrate; add 1,3-butanediol to the concentrate, stir and dissolve at 50°C for 1 hour, and the mass ratio of the concentrate to 1,3-butanediol is 1 : 1.5; sterilized at 85° C. for 30 minutes after filtering through a filter plate. ...
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