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Medicine for treating liver-depression and phlegm-stasis type mammary gland hyperplasia and preparation method

A technique for breast hyperplasia and liver stagnation and phlegm coagulation, which is applied in the field of pharmacy, can solve the problems of unacceptable patients, endocrine balance disorders, high price, etc., and achieves the effects of convenient administration route, easy acceptance and simple production.

Inactive Publication Date: 2015-07-08
SHANDONG PROVINCIAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] 3. Human factors or bad living habits: female infertility due to advanced age, sexual life disorders, induced abortion, marital disharmony, non-breastfeeding and other reasons, resulting in normal and periodic physiological activities of the mammary glands
[0008] 4. Unreasonable dietary structure: such as high-fat and high-energy diets lead to excessive fat intake, and bad living habits such as drinking and smoking can induce breast disease
[0009] 5. Long-term use of estrogen-containing health care products and contraceptives: Long-term excessive intake of estrogen by the human body will lead to endocrine imbalance. Now some fast-growing foods, artificially raised aquatic products and feed for poultry also contain hormone ingredients. Long-term Eating can also lead to breast disease
[0015] However, western medicine has unsatisfactory curative effect, relatively large toxic and side effects, easy relapse, surgical treatment is relatively traumatic, expensive, causes certain economic pressure to patients, and is difficult for patients to accept, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0077] When the dosage form of described medicine is honey refining pill, its preparation method may further comprise the steps:

[0078] Step 1: firstly mix Toosendan, Augusta, Cyperus cyperi, Bergamot, Lvca plum, Lathyrus lentils and Sala in the stated ratio, and distill and crystallize to obtain powder;

[0079] Step 2: Take the remaining raw materials and mix them according to the ratio, add 2-6 times the amount of 83-94% ethanol to soak for 1-2 hours, heat and extract twice, each time for 1-1.5 hours, and combine the extracts , 124-150 mesh filtration, and then ultrafiltration through an ultrafiltration column with a cut-off molecular weight of 4400-98000, and the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.04 at 87°C, which becomes component 1;

[0080] Step 3: Soak the drug residue in step 2 with 4-6 times the amount of water for 1-2.5 hours, extract once, the extraction time is 1.5-2 hours, concentrate and filter to o...

Embodiment 1

[0092] Embodiment 1 honey refining pill of the present invention

[0093] Take 17g of Toosendan, 22g of August Zha, 22g of Cyperus Cyperi, 25g of Bergamot, 14g of Lvcai Mei, 15g of Lathyrus, 17g of Salozi, 22g of Curcuma, 16g of Turmeric, 25g of Salvia, 22g of C. Liuxing 30g, Frangipani 23g, Lingxiaohua 23g, Curcuma 18g, Sorrel 19g, Betel 23g, Pangolin 15g, Xintahua 7g, Hericium erinaceus 10g, Polygala 6g, Albizia Julibrissin 12g, Rock cabbage 24g, Low ground tea 25g , 14g of corrugated seeds, 18g of geranium yellow and 23g of uncaria.

[0094] Its preparation method comprises the following steps:

[0095] Step 1: firstly mix Toosendan, Augusta, Cyperus cyperi, Bergamot, Lvca plum, Lathyrus lentils and Sala in the stated ratio, and distill and crystallize to obtain powder;

[0096] Step 2: Take the remaining raw materials and mix them according to the stated ratio, add 3 times the amount of 90% ethanol to the mixture, soak for 1 hour, heat and extract twice, each time for 1 ...

Embodiment 2

[0099] Embodiment 2 Tablet of the present invention

[0100] Take 20g of Toosendan, 30g of August Zha, 31g of Rhizoma Cyperi, 32g of Bergamot, 25g of Plum, 23g of Mucuna, 20g of Salo, 25g of Curcuma, 11g of Turmeric, 38g of Salvia, 25g of C. Liuxing 20g, Frangipani 18g, Lingxiaohua 31g, Curcuma 26g, Frangipani 16g, Betel 19g, Pangolin 24g, Xintahua 11g, Hericium erinaceus 14g, Polygala 8g, Albizia Julibrissin 15g, Rock cabbage 17g, Low ground tea 27g , Corrugated seeds 20g, Geranium yellow 13g and Uncaria 18g.

[0101] Its preparation method comprises the following steps:

[0102] The first step is to mix the raw materials of the drug in proportion, add ethanol with an alcohol concentration of 90% that is 4 times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 95% relative to the quality of the dregs, heat and reflux for 1 hour, extract, and filt...

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PUM

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Abstract

The invention discloses a medicine for treating hyperplasia of mammary glands with stagnation of liver stagnation and phlegm and a preparation method thereof, wherein the medicine comprises the following raw materials: Toosendan, August Zha, Rhizoma Cyperi, Bergamot, Lvca Plum, Lathyrus arborescens, Sorrel Luozi, turmeric, turmeric, salvia miltiorrhiza, chinensis, buliuxing, frangipani, lingxiaohua, zedoary, scalloped lily, mountain betel, pangolin, xinta flower, Hericium erinaceus, polygala, acacia bark, rock cabbage, Dwarf ground tea, corrugated seeds, geranium yellow, uncaria. The beneficial effects of the invention are: the medicine of the invention has the effects of soothing the liver and relieving stagnation, resolving phlegm and resolving stagnation, and is mainly used for the syndrome of hyperplasia of mammary glands due to stagnation of liver and phlegm. Utilize traditional Chinese medicine theory, pay attention to the overall concept, regulate the generation and operation of the body's qi and blood, and at the same time treat based on syndrome differentiation. According to different clinical manifestations, focus on treatment, quick effect, wide range of drug sources, low price, simple preparation, convenient administration route, easy for patients Accepted, clinical marketing can be carried out.

Description

Technical field [0001] The invention involves the field of pharmacy and technology, and specially involves a drug and preparation method for the treatment of liver stagnation and phlegm -type breast hyperplasia. Background technique [0002] Breast hyperplasia refers to the hyperplasia of the breast epithelium and fibrous tissue, the degenerative lesions of the mammary tissue catheter and the milk leaflets of the milk and the growth of the tissue of sexual connective tissue.It is the most common breast disease for women and should be prevented in advance. [0003] 1. Cause: [0004] At present, the cause of breast hyperplasia is not completely clear, and it may be related to endocrine disorders, spiritual, and environmental factors. [0005] 1. Endocrine disorders: decreased lutein secretion, and the increase in estrogen is an important cause of breast hyperplasia.Such as poor ovarian development, irregular menstruation, thyroid disease and liver dysfunction. [0006] 2. Emotiona...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P15/14A61K35/36A61K35/618
CPCA61K9/2059A61K9/2068A61K9/7076A61K35/36A61K35/618A61K36/06A61K36/185A61K36/36A61K36/428A61K36/48A61K36/53A61K36/537A61K36/58A61K36/60A61K36/63A61K36/67A61K36/69A61K36/736A61K36/74A61K36/752A61K36/8905A61K36/899A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 宗园媛
Owner SHANDONG PROVINCIAL HOSPITAL
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