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Three-dimensional nanocomposite adhesive bandage as well as preparation method and use method thereof

A composite material and three-dimensional nanotechnology, which is applied in textiles and papermaking, medical science, bandages, etc., can solve the problems of secondary injury of wounds, dressings can not fit, etc., to reduce the waste of drugs, not easy to damage the wound surface, superior protection Effect

Active Publication Date: 2015-03-04
SHANDONG PROVINCIAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The purpose of the present invention is to solve the problem that the existing dressing cannot fully fit the uneven wound surface, and the dressing adheres to the wound, causing secondary damage to the wound when the dressing is removed. Products for Ideal Dressing Requirements

Method used

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  • Three-dimensional nanocomposite adhesive bandage as well as preparation method and use method thereof
  • Three-dimensional nanocomposite adhesive bandage as well as preparation method and use method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] Such as figure 1 , figure 2 As shown, a three-dimensional nanocomposite material band-aid includes a three-dimensional maintenance wound layer and a breathable adhesive plaster layer 3, wherein the three-dimensional maintenance wound surface is composed of a nanofiber film 1 containing chitosan and a nano-bacterial cellulose freeze-dried film 2.

[0054] The preparation process of the three-dimensional nanocomposite band-aid is as follows:

[0055] Step 1. Pretreatment and purification of the nano-bacterial cellulose membrane: take the nano-bacterial cellulose and rinse it with clear water several times to remove the medium and impurities on the surface of the nano-bacterial cellulose membrane; then soak the nano-bacterial cellulose membrane in 0.1 mol / L Boil in a sodium hydroxide solution at 110°C for 90 minutes to wash out the bacteria and residual culture medium in the nano-bacterial cellulose membrane; then rinse the bacterial cellulose membrane with distilled wat...

Embodiment 2

[0064] The band-aid prepared by the method in Example 1 is used for the protection and external treatment of chronic skin ulcer wounds, the method is mainly aimed at the sunken wounds whose bottom surface is approximately circular and has a maximum internal diameter of 5-3 cm and a depth of less than 0.7 cm.

[0065] In step 2 in embodiment 1, a freeze-dried film with a thickness greater than 0.7 centimeters and a diameter greater than 5 centimeters is selected. In step 3, the nano-bacterial cellulose freeze-dried film is trimmed into a cylindrical protrusion with a bottom diameter of 5 centimeters and a height of 0.7 centimeters. A curved surface, which can be complementary to a depressed wound with a bottom surface approximately circular, a maximum inner diameter of 5-3 cm, and a depth of less than 0.7 cm in a natural or compressed state. After completing steps 1 to 7 of Example 1, on the three-way maintenance wound layer, dripping quality is polyhexamethylene hydrochloric ac...

Embodiment 3

[0069] The band-aid prepared by the method in Example 1 is used for the protection and external treatment of bullous impetigo, the method is mainly aimed at raised pustules with a diameter of 0.5-0.8 cm and a height of 0.2-0.5 cm.

[0070] Step 2 in embodiment 1 selects thickness to be greater than 0.6 centimetre, the nano-bacteria cellulose freeze-dried film that diameter is greater than 0.9 centimeter, and in step 3, it is 0.5 centimeters that the nano-cellulose film is trimmed into the bottom surface diameter, and height is the depression of 0.2 centimeter. Spherical crown surface that complements a raised / potential wound with a diameter of 0.5-0.8 cm and a height of 0.2-0.5 cm in a natural or compressed state.

[0071] When using, first clean the surface of the pustule with medical disinfectant, remove the anti-adhesive spacer paper on the band-aid, fit the curved surface of the spherical crown of the three-way protective wound layer to the surface of the pustule, and adjus...

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Abstract

The invention discloses a three-dimensional nanocomposite adhesive bandage as well as a preparation method and a use method thereof. The three-dimensional wound-protection layer of the adhesive bandage has a curved surface, and the curved surface is complementary to the uneven wound surface and comprises a nanobacterial cellulose frozen-dried membrane and an eletrospun chitosan-containing nanofiber film. The three-dimensional wound-protection layer can carry a part of liquid medicine. When in use, the adhesive bandage fully fits the wound surface, has air permeability, can keep the wound surface wet, has the functions of stop bleeding, inhibiting bacteria, promoting the healing of a wound and preventing the adhesion of the wound surface to the wound dressing and can be used widely. The adhesive bandage can well fit the concave wound surface and the convex wound surface, is applicable to the wet wound surface with many exudates, the dry wound surface which needs to be wetted by the wound dressing and the potential wound surface which needs protection, thereby being an ideal wound dressing.

Description

technical field [0001] The invention relates to the field of wound medical dressings, in particular to a three-dimensional nanocomposite material band-aid and its preparation and use methods, belonging to the field of medical technology. Background technique [0002] The skin is an important organ of the human body, composed of epidermis, dermis and subcutaneous tissue. The basic functions of the skin have five aspects: protection function, temperature regulation function, sensory function, perspiration function and absorption function. At the same time, it has important physical, chemical and biological barrier functions. As the first barrier of the human body, the skin is extremely vulnerable to damage in daily life. Improper use of knives, falls, traffic accidents, fights, etc. may cause acute trauma to the skin; skin ulcers, especially chronic skin ulcers, as a Common diseases have a long course of disease, are difficult to cure and are prone to recurrence, which seriou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/44D04H1/728
Inventor 王萍
Owner SHANDONG PROVINCIAL HOSPITAL
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