Fully polymerized UV blocking silicone hydrogel lens

A siloxane hydrogel and ultraviolet technology, applied in glasses/goggles, instruments, and other household appliances, can solve the problems of difficult formation of ophthalmic devices and incomplete curing

Active Publication Date: 2015-02-25
BAUSCH & LOMB INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Differences in the reaction mechanisms of device-forming systems and hence Differences in reaction kinetics (e.g., addition to C=C vs. hydrogen atom transfer) make such systems particularly susceptible to incomplete cure
Therefore, the relatively sensitive kinetics of the curing reaction in these device-forming systems make it difficult to form successful ophthalmic devices

Method used

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  • Fully polymerized UV blocking silicone hydrogel lens
  • Fully polymerized UV blocking silicone hydrogel lens
  • Fully polymerized UV blocking silicone hydrogel lens

Examples

Experimental program
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example

[0055] All solvents and reagents were obtained from commercial sources identified below and used as received.

[0056] NVP - distilled

Aldrich

CIX-4

Novasep

DMA - Distilled

Aldrich

Irg 819

Aldrich

Hexanol

Sigma Aldrich

nonanol

Aldrich

SA monomer

Aldrich

BTT

Aldrich

BPA-2

Polysciences Inc

BPM-2

Monomer-Polymer and Dajac Labs

BPA-1

Aldrich

Reactive Blue Tint = 1MVT

Arran

M1-EDS-6

Gelest

Ma1D20

Gelest

HEMA

Cyro Industries

[0057]

[0058] Methacryloxypropyltris(trimethylsiloxy)silane

[0059] TRIS

[0060]

[0061] Ma2D37

[0062]

[0063] N-vinylpyrrolidone

[0064] NVP

[0065]

[0066] Diethylene glycol bis(N-vinylbenzylcarbamate)

[0067] CIX-4

[0068]

[0069] N,N-Dimethacrylamide

[0070] DMA

[0071]

[0072] IRG819 (photoinitiator)

[0073]

[0074] SA monomer (UV blocker)...

Embodiment approach

[0192] 1(a). A method for making a substantially fully polymerized UV blocking hydrogel lens comprising:

[0193] A monomer mixture of at least NVP, one additional comonomer, and a free radically polymerizable bis-o-hydroxybenzophenone is polymerized to provide a hydrogel ophthalmic device having a wettable surface.

[0194] 1(b). A method for making a substantially fully polymerized UV blocking hydrogel lens comprising:

[0195] Polymerizing a monomer mixture of at least NVP, an additional comonomer, and a radically polymerizable di-ortho-hydroxybenzophenone to provide a UV-blocking compound having sufficient UV blocking to meet at least Class II specifications for UV blocking. Hydrogel Ophthalmic Devices.

[0196] 1(c). A method for preparing a substantially fully polymerized UV-blocking hydrogel lens comprising adding at least one monomer selected from the group consisting of monomers, at least one A monomer mixture of an additional comonomer and a free radically polymeri...

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PUM

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Abstract

A substantially fully copolymerized UV blocking hydrogel lens demonstrating sufficient blocking of UV light to meet at least FDA Class II specifications for UV blocking formed from a reaction mixture comprising at least NVP and one other comonomer and a free-radical polymerizable, substituted or unsubstituted, Bis Omicron-hydroxy benzophenone is provided herein.

Description

technical field [0001] The present invention relates to an ophthalmic device, and more particularly to a process for preparing a substantially fully polymerized UV-blocking hydrogel lens comprising incorporating at least one (NVP), one additional comonomer and monomer mixtures of free radically polymerizable substituted or unsubstituted di-ortho-hydroxybenzophenones are polymerized to provide a surface that has a wettability and is sufficiently UV-blocking to meet at least Class II specifications for UV-blocking Hydrogel Ophthalmic Devices. Background technique [0002] The development of commercially successful ophthalmic devices formed from traditional silicone hydrogel materials often requires post-curing of the resulting wettable surfaces. Traditional silicone hydrogel contact lenses can exhibit superficialization of silicone chains, ie, silicone-rich microdomains reside on the lens surface. Surfaceization of the siloxane chains creates hydrophobic regions on the lens ...

Claims

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Application Information

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IPC IPC(8): G02B1/04B29D11/00
CPCG02B1/043B29D11/00038C08L39/06B29D11/00C08J7/00G02B1/04G02C7/04
Inventor I·M·努涅斯J·亨特
Owner BAUSCH & LOMB INC
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