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Cod liver oil ointment for treating hemorrhoids and anal fissure

A technology of cod liver oil and anal fissure, which is applied in the directions of ointment delivery, non-living material medical raw materials, medical preparations containing active ingredients, etc. Fast onset, good quality results

Inactive Publication Date: 2015-02-18
中山百鸥医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are many drugs for the treatment of hemorrhoids and anal fissure, but they have the disadvantages of slow effect, incomplete, easy recurrence, complex prescriptions, and side effects on the body.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Preparation method of seal liver oil

[0019] 1) Storage of seal liver: the seal liver, a by-product of seal processing, is cleaned and stored in a freezer below -18~-22°C;

[0020] 2) Pretreatment: thaw the seal liver and chop it;

[0021] 3) Enzymolysis: Add water to the hydrolysis pot to make the liquid-solid ratio (mL / g) 1:1-2:1, add hydrochloric acid to adjust the pH to 5.5-6.5, add 1.5-2.5% (mass) of seal liver Papain, sealed, placed in a constant temperature oscillator, enzymatically hydrolyzed for 3-4 hours at a speed of 100-150r / min and a temperature of 40-50°C;

[0022] 4) Centrifugal separation after enzymatic treatment: After enzymatic hydrolysis, add hydrochloric acid to adjust the pH to 3-3.5 to denature and inactivate the complex protease, put it in a low-speed large-capacity centrifuge, and centrifuge while it is hot at a speed of 4000-5000r / min After 5-15 minutes, the upper layer of crude seal liver oil was separated; the middle lipoprotein emulsion p...

Embodiment 2

[0026] A cod liver oil ointment for treating hemorrhoids and anal fissure, which is made of the following raw materials in parts by weight: 85 parts of seal liver oil, 40 parts of musk, 40 parts of zinc oxide, 37 parts of alum, 1 part of borneol, 1.5 parts of azone, and 2 parts of vaseline share.

[0027] A preparation method of cod-liver oil ointment for treating hemorrhoids and anal fissures. The raw materials of 40 parts of musk, 40 parts of zinc oxide and 37 parts of alum are crushed and sieved for later use; 1 part of borneol, 1.5 parts of azone and 2 parts of melted vaseline are added Into the fine powder after the above pulverization, stir, add 85 parts of seal cod liver oil in the stirring process, mix until semi-solidified.

Embodiment 3

[0029] A cod liver oil ointment for treating hemorrhoids and anal fissure, which is made of the following raw materials in parts by weight: 110 parts of seal liver oil, 20 parts of musk, 60 parts of zinc oxide, 15 parts of alum, 2 parts of borneol, 0.5 part of azone, and 3 parts of vaseline share.

[0030] A preparation method of cod-liver oil ointment for treating hemorrhoids and anal fissures. The raw materials of 20 parts of musk, 60 parts of zinc oxide and 15 parts of alum are pulverized and sieved for later use; 2 parts of borneol, 0.5 parts of azone and 3 parts of melted vaseline are added Add to the fine powder after pulverization, stir, add 110 parts of seal cod liver oil in the stirring process, and mix until semi-solidified.

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PUM

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Abstract

The invention relates to the technical field of drugs, in particular to a cod liver oil ointment for treating hemorrhoids and anal fissure. The cod liver oil ointment is prepared from the following raw materials in parts by weight: 85 to 100 parts of seal liver oil, 20 to 40 parts of musk, 40 to 60 parts of zinc oxide, 15 to 37 parts of alum, 1 to 2 parts of borneol, 0.5 to 1.5 parts of azone, and 2 to 3 parts of Vaseline. The cod liver oil ointment provided by the invention is easily applied to infected parts, protects wounds, promotes wound healing, diminishes inflammation and alleviates itching, has the efficacy of removing slough, promoting tissue regeneration, realizing astringency, diminishing inflammation, relieving itching, clearing away heat and alleviating pain, and promoting wound healing, has obvious curative effects on treating mucocutaneous ulcer and perianal ache, itchiness and red and swollen, has small side effects, has the advantages of exact curative effect, good convenience in use, rapidness in taking effect, high safety, painless, good quality and the like, and is superior to the prior art and the effective rate can reach 100 percent.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to cod liver oil ointment for treating hemorrhoids and anal fissures. Background technique [0002] Anal fissure is a prismatic fissure or ulcer formed by the rupture of the anal canal skin below the dentate line. It is mostly caused by constipation, excessive defecation, and rupture of the anal skin. From the perspective of infection, it is mainly the anal crypt infection at the back of the anus, and the inflammation spreads to the subcutaneous part of the anal canal, resulting in the rupture of subcutaneous abscess and anal fissure. Anal fissure can cause perianal redness, perianal ulcer, perianal pain and other perianal diseases. [0003] Hemorrhoids (haemorrhoids) are soft veins formed by the flexion and expansion of the hemorrhoidal venous plexus under the mucosa of the end of the rectum and the skin of the anal canal. It is a common disease and frequently-occurring diseas...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/55A61K9/06A61P17/02A61P9/14A61P1/00A61K33/06A61K31/045A61K33/30A61K35/407
CPCA61K35/407A61K9/06A61K31/045A61K33/06A61K33/30A61K35/06A61K35/55A61K2300/00
Inventor 刘巴宁
Owner 中山百鸥医药科技有限公司
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