Montelukast sodium tablet and preparation method thereof
A technology of montelukast sodium tablet and montelukast sodium, which is applied in the field of medicine, can solve problems such as light sensitivity, and achieves the effects of good stability, rapid disintegration and simple preparation process
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Embodiment 1
[0025]
[0026] Preparation Process:
[0027] Dissolve the montelukast sodium and trehalose in ethanol in the prescribed amount, dry under reduced pressure at 40°C to remove the ethanol, pass the dried product (that is, a dispersion-like compound) through a 60-mesh sieve, and then mix it with the prescribed amount of alginic acid, micro Crystalline cellulose and magnesium stearate are mixed and compressed into tablets.
Embodiment 2
[0029]
[0030] Preparation Process:
[0031] Dissolve the montelukast sodium and trehalose in ethanol in the prescribed amount, dry under reduced pressure at 45°C to remove the ethanol, pass the dried product through an 80-mesh sieve, and then mix with the prescribed amount of alginic acid, microcrystalline cellulose, and magnesium stearate Mix and compress into tablets.
Embodiment 3
[0033]
[0034] Preparation Process:
[0035] Dissolve montelukast sodium and trehalose in ethanol for the prescription amount, place in a rotary evaporator, dry under reduced pressure at 35°C to remove ethanol, pass the dried product through an 80-mesh sieve, and then mix with alginic acid, lactose, Magnesium stearate is blended and compressed into tablets.
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