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Kit for rapid early-to-mid diagnosis of ovarian cancer and detection method thereof

A rapid diagnosis and kit technology, applied in disease diagnosis, measuring devices, instruments, etc., can solve problems such as low sensitivity and accuracy, lower patient survival rate, missed treatment opportunities, etc., to achieve good differential diagnosis, high sensitivity, The effect of strong accuracy

Active Publication Date: 2014-07-30
GUANGZHOU HENGTAI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the diagnostic kits for ovarian cancer in hospitals are used to detect common tumor markers, and their sensitivity and accuracy are low. Even joint inspections are only about 70%, which is difficult to meet the requirements of early and rapid diagnosis.
[0005] Since there is no rapid and efficient diagnostic kit for ovarian cancer on the market, it seriously affects the early detection and treatment of ovarian cancer. When ovarian cancer patients are diagnosed, they are often in the advanced stage of cancer, missing the best time for treatment, and greatly reducing the survival of patients. Rate

Method used

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  • Kit for rapid early-to-mid diagnosis of ovarian cancer and detection method thereof
  • Kit for rapid early-to-mid diagnosis of ovarian cancer and detection method thereof
  • Kit for rapid early-to-mid diagnosis of ovarian cancer and detection method thereof

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Embodiment Construction

[0057] The following is a detailed description of the rapid diagnosis kit for early and mid-stage ovarian cancer of the present invention in conjunction with the accompanying drawings and specific examples.

[0058] It is used for early and mid-stage rapid diagnosis kit of ovarian cancer, including capture antibody, capture antibody blocking buffer, standard, labeled antibody, washing solution and chromogenic solution, etc. The labeled antibody is selected HRP standard Secondary antibody . The capture antibodies include monoclonal antibodies prepared respectively from galectin-3, transthyretin (TTR) and cancer antigen-125 (CA-125); The joint rapid detection of (TTR) and cancer antigen-125 (CA-125) can effectively improve the detection accuracy and sensitivity, and effectively overcome the shortcomings caused by the detection of cancer antigen-125 (CA-125) alone.

[0059] The capture antibody also includes a monoclonal antibody made with human epididymis protein 4 (HE4), t...

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PUM

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Abstract

The invention discloses a kit for rapid early-to-mid diagnosis of ovarian cancer. The kit comprises monoclonal antibodies which are respectively prepared from galectin-3, transthyretin, a cancer antigen-125 and human epididymis protein 4; and the kit also comprises a detection antibody, wherein the detection antibody comprises polyclonal antibodies which are respectively prepared from galectin-3, transthyretin, cancer antigen-125 and human epididymis protein 4. The kit has the beneficial effects that the ovarian cancer can be comprehensively detected, benign and malignant pelvic masses before or after menopause can be well judged, gynecological benign ovarian mass and cyst and ovarian cancer can be well identified and judged, the kit has the characteristics of high sensitivity and high accuracy, and the sensitivity and accuracy are above 96 percent.

Description

Technical field: [0001] The invention relates to the field of kits for cancer diagnosis and detection, in particular to a rapid diagnosis kit for early and mid-stage ovarian cancer and a detection method thereof. Background technique: [0002] Ovarian malignant tumor is one of the common malignant tumors of female reproductive organs, which refers to malignant tumors growing on the ovary, and 90% to 95% of them are primary ovarian cancers. 60% to 70% of them are advanced when they go to the doctor, and the curative effect of advanced cases is not good. Therefore, although the incidence rate of ovarian cancer is lower than cervical cancer and endometrial cancer, ranking third among gynecological malignancies, its mortality rate exceeds the sum of cervical cancer and endometrial cancer, ranking first among gynecological cancers, and is a serious threat to women. greatest disease of health. [0003] Due to the complex embryonic development, tissue anatomy and endocrine functi...

Claims

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Application Information

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IPC IPC(8): G01N33/577G01N33/531
CPCG01N33/57449G01N33/57484G01N2800/36G01N2800/52
Inventor 余跃飞罗喜平王晓娟
Owner GUANGZHOU HENGTAI BIOTECH
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