Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine ultramicro wall-breaking fine powder for treating stomach disease

A technology of ultra-fine wall breaking and fine powder, which is applied in powder delivery, drug combination, pharmaceutical formulation, etc., and can solve the problems of low content of active ingredients, low dissolution rate, and influence on therapeutic effect

Active Publication Date: 2014-07-23
TIANJIN ZHONGRUI PHARMA
View PDF3 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Stomach disease is difficult to cure, but it often recurs after a period of treatment, seriously affecting physical and mental health
Existing traditional Chinese medicines for treating stomach diseases are generally prepared by boiling at high temperature. The biological activity of Chinese medicinal materials in the boiling liquid is easily destroyed, the dissolution rate is not high, and the content of active ingredients is not high, which affects the therapeutic effect.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine ultramicro wall-breaking fine powder for treating stomach disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] 1) Raw material processing: Weigh 20% white lentils, 15% dry squid ink sac powder, 27% fried jujube seed powder, 12% roasted licorice, 12% atractylodes 12%, and dried tangerine peel 14% according to the weight percentage. After mixing the roasted licorice, atractylodes, and tangerine peel, pulverize with a grinder, pass through a 30-mesh sieve, add dried squid ink sac powder and fried jujube seed powder to mix;

[0027] 2) Broken wall pulverization: the mixed dry powder in step 1) is pulverized to 50μm by an ultrafine grinder to obtain broken wall fine powder;

[0028] 3) Wet ball mill pulverization: Add the fine powder obtained in step 2) into a ball mill for wet ball mill pulverization. The weight ratio of fine powder raw material to water is 1:3, and the speed of the ball mill is 200 rpm. After 2 hours of ball milling, the wall is broken to obtain a ball mill Broken powder

[0029] 4) Add the ball mill broken wall powder in step 3) and soak in water 5 times the weight of t...

Embodiment 2

[0033] 1) Raw material processing: Weigh 30% white lentils, 20% dried squid ink sac powder, 20% fried jujube seed powder, 9% roasted licorice, 9% atractylodes, and 12% tangerine peel according to the weight percentage. After mixing the roasted licorice, atractylodes, and tangerine peel, pulverize with a pulverizer, pass through a 50-mesh sieve, add dried squid ink sac powder and fried jujube seed powder to mix;

[0034] 2) Broken wall pulverization: The mixed dry powder in step 1) is pulverized to 100μm by an ultrafine pulverizer to obtain broken wall fine powder;

[0035] 3) Wet ball mill pulverization: Add the fine powder obtained in step 2) into the ball mill for wet ball mill pulverization. The weight ratio of the fine powder raw material to water is 1:5, the speed of the ball mill is 300 rpm, and the wall is broken after 3 hours of ball milling to obtain a ball mill Broken powder

[0036] 4) Add the ball milled wall powder in step 3) to 6 times the weight of the raw material an...

Embodiment 3

[0040] 1) Raw material processing: weigh 25% white lentils, 17% dried squid ink sac powder, 24% fried jujube seed powder, 10% roasted licorice, 11% atractylodes, and dried tangerine peel 13% according to the weight percentage. After mixing the roasted licorice, atractylodes and tangerine peel, pulverize with a pulverizer, pass through a 30-50 mesh sieve, add dried squid ink sac powder and fried jujube seed powder to mix;

[0041] 2) Broken wall pulverization: the mixed dry powder in step 1) is pulverized to 80 μm by an ultrafine pulverizer to obtain broken wall fine powder;

[0042] 3) Wet ball mill pulverization: Add the fine powder obtained in step 2) to a ball mill for wet ball mill pulverization. The weight ratio of the fine powder raw material to water is 1:4, the speed of the ball mill is 250 rpm, and the wall is broken after 2.5 hours of ball milling to obtain a ball mill Broken powder

[0043] 4) Add the ball mill broken wall powder in step 3) to water 5.5 times the weight o...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a traditional Chinese medicine ultramicro wall-breaking fine powder for treating a stomach disease, and belongs to the technical field of the traditional Chinese medicine. A preparation method of the traditional Chinese medicine ultramicro wall-breaking fine powder comprises the following steps: (1) treating raw materials; (2) breaking walls and grinding; (3) carrying out wet-process ball milling, and grinding; (4) decocting and filtering; (5) carrying out vacuum thin film concentration and drying on the filtrate; and (6) carrying out high temperature sterilization. The traditional Chinese medicine ultramicro wall-breaking fine powder for treating the stomach disease is prepared by compounding natural food materials and medicinal materials which have the effects of tonifying spleen and reinforcing stomach and synergistic interaction effects on the stomach disease; the natural food materials and medicinal materials are made into fine powder by adopting ultramicro wall breaking, so that the damage on nutritional materials and functional components in the product in a processing process is reduced, and original bioactive components and functional components are greatly retained; the traditional Chinese medicine ultramicro wall-breaking fine powder is small in particle size, good in uniformity and high in dissolution rate; the dissolution and absorption speed of the traditional Chinese medicine ultramicro wall-breaking fine powder in bodies can be accelerated, the absorptive amount of the traditional Chinese medicine ultramicro wall-breaking fine powder is increased, and therefore, the traditional Chinese medicine ultramicro wall-breaking fine powder has a good treatment effect on the stomach disease.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine ultrafine broken wall powder for treating gastric diseases. Background technique [0002] Stomach disease can be mild or severe. The most common symptoms are upper abdominal discomfort or pain, nausea, vomiting, diarrhea, and loss of appetite. The symptoms of gastritis and duodenal ulcer are burning pain in the upper abdomen, especially between two meals, before breakfast or after drinking orange juice or coffee. In severe cases, there may be tarry stools, black stools or bloody stools. Stomach disease is difficult to cure, but it often recurs after a period of treatment, which seriously affects physical and mental health. Existing traditional Chinese medicines for the treatment of gastric diseases are generally prepared by high-temperature boiling, and the biological activity of the Chinese medicinal materials in the boi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K9/14A61P1/00A61P1/04A61K35/56A61K35/618
Inventor 王建荣
Owner TIANJIN ZHONGRUI PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products