20(R)-ginsenoside Rg3 preparation for external use, preparing method thereof and applications thereof

An external preparation, ginsenoside technology, applied in the field of 20-ginsenoside Rg3 active ingredient, can solve the problems of full play, unexplainable, unfavorable efficacy, etc., and achieve the effect of rapid dysmenorrhea, unique formula, and high safety

Active Publication Date: 2014-06-11
富力
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the existing studies, ginseng and its total saponins are mostly used as the main active ingredients of external preparations. The components of ginseng and total ginsenosides are very complicated. When various functional components are mixed together, some adverse reactions often occur and cannot be explained clearly. It is not conducive to the full play of efficacy; while monomeric saponins have the characteristics of clear effect, low side effects, and less dosage, so monomeric ginsenosides are used as the main active ingredient of external preparations, especially in cosmetic products, which have more commercial value and health significance

Method used

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  • 20(R)-ginsenoside Rg3 preparation for external use, preparing method thereof and applications thereof
  • 20(R)-ginsenoside Rg3 preparation for external use, preparing method thereof and applications thereof
  • 20(R)-ginsenoside Rg3 preparation for external use, preparing method thereof and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Embodiment 1 Rg3 cream

[0043] 1. Prepare raw materials according to the following ratio

[0044] 1) Prepare the raw materials of part A according to the following ratio:

[0045]

[0046] 2) Prepare part B raw materials according to the following ratio:

[0047]

[0048] 2. Mix the raw materials of parts A and B under stirring state, heat up and keep it at 70°C, after stirring evenly, add the mixed raw materials of part B into the raw materials of part A while stirring while keeping the temperature at 70°C , after stirring evenly, add deionized water to 100%, and cool to room temperature to prepare Rg3 moisturizing cream 100g, 20g / bottle.

Embodiment 2

[0049] Embodiment 2 Rg3 cream

[0050] 1. Prepare raw materials according to the following ratio

[0051] 1) Prepare the raw materials of part A according to the ratio:

[0052]

[0053]

[0054] 2) Prepare the raw materials of Part B according to the ratio as follows:

[0055]

[0056] 3) Prepare the raw materials of part C according to the ratio:

[0057]

[0058] 2. Mix the raw materials of parts A and B respectively under stirring, heat and keep them at 70°C. After stirring evenly, add the mixed raw materials of part B to the raw materials of part A while stirring while keeping the temperature at 70°C. After stirring evenly, add the raw materials of part C, mix evenly, add deionized water to 100%, cool to room temperature, and prepare Rg3 sunscreen 100g, 20g / bottle.

Embodiment 3

[0059] Embodiment 3 Rg3 gel

[0060] 1. Prepare raw materials according to the following ratio

[0061]

[0062] The whole party finally added deionized water to 100%.

[0063] 2. Add carbomer to deionized water, stir and swell, add ginsenoside Rg3, EDTA-Na2, essence, propylparaben, methylparaben, stir evenly, and use a mass percentage concentration of 10 % sodium hydroxide solution to adjust the pH of the mixed solution is 6 (pH is 5 ~ 7 is also applicable to the present invention), stir, add deionized water to 100%, make Rg3 gel 100ml, 10g / support.

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PUM

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Abstract

The invention relates to different formulas comprising an active component 20(R)-ginsenoside Rg3 and a plurality of auxiliary materials, or relates to a plurality of preparations for external use prepared by adding other active components into the formulas. The formulas and the preparations for external use can be used for medicines or cosmetics, and can be used for treating dysmenorrhea and leucoderma through an external use administration manner.

Description

technical field [0001] The present invention relates to a combination formula of 20(R)-ginsenoside Rg3 active ingredient and various auxiliary materials to make various external preparations; the external preparation formula of the present invention is not limited to 20(R)-ginsenoside Rg3 as an active ingredient, but also It can be a combination formula of 20(R)-ginsenoside Rg3 and other active ingredients. These active ingredients can be Panax notoginseng, aloe vera, licorice, Shouwu, ginkgo, black sesame extract, ginger extract, grape seed extract, pomegranate seed One, two or more of extracts, plant essential oils, arbutin, vitamin C and its derivatives, vitamin E and its derivatives. The formula and the external preparation thereof of the present invention can be used in pharmaceutical external dosage forms or cosmetics, and can be used for treating vitiligo. Background technique [0002] Ginseng is a plant belonging to the genus Panax in the Araliaceae family. It has b...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K9/10A61K9/12A61K9/70A61K31/704A61K36/9068A61K36/896A61K36/87A61K36/484A61K36/258A61K36/185A61P15/00A61P17/00A61K31/7034A61K31/375A61K31/355
Inventor 富力刘正贤王凯乾王典仁鲁明明柳杨鲁岐惠敏冯雪
Owner 富力
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