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Recurrent oral ulcer power

A technology for oral ulcers and recurrence, which is applied in the field of medicine, can solve the problems of low clinical cure rate of medicines, toxic and side effects of patients, and inability to cure the root cause, etc., and achieves the effects of remarkable and reliable curative effect, simple preparation, and low cost

Active Publication Date: 2014-05-14
HAIMEN CITY RUITAI TEXTILE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In recent years, some traditional Chinese medicine compound medicines for the treatment of this disease according to the principle of treating the stomach and purging the spleen have appeared in this field, such as Kouyanqing Capsules, Oral Ulcering Capsules, Huanglian Shangqing Pills, and Sanlian Tablets. The treatment of ulcer disease has a certain curative effect in some aspects, but generally speaking, the clinical cure rate of these drugs is low, the recurrence rate is extremely high, and they cannot cure the root cause, and some drugs also have toxic and side effects on patients

Method used

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  • Recurrent oral ulcer power

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A traditional Chinese medicine preparation for recurrent oral ulcer, which is prepared from the following raw materials in weight ratio:

[0030] 35 parts of Ophiopogon japonicus, 35 parts of mountain bean root, 35 parts of dandelion, 30 parts of mother-in-law needle, 30 parts of cassia twig,

[0031] 30 parts of Cao Guo, 30 parts of Epimedium, 27 parts of Trichosanthes, 27 parts of Paeoniae Alba, 25 parts of Chuanxiong,

[0032] 25 parts of Dijincao, 25 parts of Citrus aurantii, 25 parts of Poria cocos, 25 parts of Zhuru, 20 parts of Fangfeng,

[0033] Nepeta 20 parts, Coptidis 20 parts, Qingdai 20 parts, Digupi 20 parts, Pao Jiang 18 parts,

[0034] 18 parts of Puhuang, 15 parts of mulberry leaves, 10 parts of Cyperus cyperi, 10 parts of tangerine peel, 10 parts of Baibu,

[0035] 7 parts of burdock fruit, 7 parts of Houttuynia cordata, and 7 parts of woody fragrance.

[0036] Above-mentioned Chinese medicine preparation preparation method is:

[0037] (1) Take th...

Embodiment 2

[0042] zoology experiment

[0043]The acute toxicity test using mice showed that compared with the control group, there was no significant difference in the mice after administration. The experiment was observed for two consecutive weeks, and the general condition, food intake, drinking water, and weight gain of the mice were all normal. On the day of administration and within two weeks after administration, no animal died, suggesting that the drug has low acute toxicity and is safe for clinical use.

[0044] long-term toxicity test

[0045] Select 40 SD rats, half male and half male. According to body weight, be divided into 2 groups at random, i.e. control group, Chinese medicine group of the present invention. 20 in each group, half male and half male. Animals in each group were intragastrically administered once a day. After continuous administration for 1 month, 10 animals in the control group were killed; 10 animals in the control group were killed during the recovery...

Embodiment 3

[0047] clinical information:

[0048] Materials and methods: In order to further investigate the clinical efficacy and safety of the traditional Chinese medicine preparation of the present invention, we selected 102 patients with recurrent oral ulcers to conduct clinical observation on the efficacy of the medicine of the present invention. Randomly divided into treatment group 51 cases, control group 51 cases; age 18-55 years old, average age 37 years old, there is no significant difference between the two groups in terms of gender, age, course of disease, etc., comparable.

[0049] standard constrain

[0050] Recurrent oral mucosal ulcers (more than 10 episodes per year) for more than 1 year in a row; pain, burning, dry mouth and bad breath of ulcers that occur on the lips, oral mucosa, gums, and tongue. The number of ulcers is 1-5, which can be seen Exudation, hyperemia, and edema are the main manifestations.

[0051] treatment method

[0052] The treatment group was give...

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Abstract

The invention relates to a pure traditional Chinese medicine preparation for recurrent oral ulceration. A recurrent oral ulcer power is prepared by radix ophiopogonis, subprostrate sophora roots, dandelions, bidens bipinnata, cassia twigs, amomum tsaoko, epimedium herb, trichosanthes kirilowii, white paeony root, ligusticum wallichii, humifuse euphorbia herb, fructus aurantii, indian buead, bamboo shavings, Chinese parsnip roots, schizonepeta, coptis chinensis, indigo naturalis, cortex lycii radicis, baked gingers, cattail pollen, folium mori, cyperus rotundus, orange peel, radix stemonae, burdocks, houttuynia cordata and costustoot. The pure traditional Chinese medicine preparation for the relates to a pure traditional Chinese medicine preparation for recurrent oral ulceration is short in treatment course and high in total efficiency, enables ulceration not to easily relapse. In addition, a process is simple, the production cost is reduced, and the economic burden of a patient is relieved.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a recurrent oral ulcer powder. Background technique [0002] Oral ulcer disease is also called "oral sore" in traditional Chinese medicine. It is a disease of the oral mucosa with a high incidence and recurrence rate. The size can range from rice grains to soybeans, and it can be round or oval. The ulcer surface is oral ulcer Concave and hyperemia around it rank first among all oral diseases today. Oral ulcer disease is clinically characterized by one or several isolated round or oval superficial ulcers on the oral mucosa, often accompanied by burning pain, especially when chewing, talking, and touching sour, spicy and other irritating foods. as obvious. For patients, oral ulcer disease is not fatal, but it brings great pain to their work and life, especially for some patients who often relapse or cannot be cured for a long time, it not only leads to mental distre...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/14A61P1/02
Inventor 王爱文王有彬许传通
Owner HAIMEN CITY RUITAI TEXTILE TECH CO LTD
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