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Traditional Chinese medicine composition for treating dementia and preparation method thereof

The technology of a composition and a traditional Chinese medicine preparation is applied in the field of traditional Chinese medicine composition for treating dementia and its preparation field, and can solve the problems such as no treatment for vascular dementia.

Active Publication Date: 2014-03-26
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although studies have shown that a single medicinal material has the effect of treating dementia, there is no report on the combination of two or three combinations of Xia Wu, turmeric and clove for the treatment of vascular dementia

Method used

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  • Traditional Chinese medicine composition for treating dementia and preparation method thereof
  • Traditional Chinese medicine composition for treating dementia and preparation method thereof
  • Traditional Chinese medicine composition for treating dementia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0170] Take 15kg of Xiawu, 15kg of turmeric, and 15kg of cloves, add 12 times the amount of water, decoct and extract 3 times, 1 hour each time, filter the water extract, combine, concentrate, add conventional pharmaceutical excipients to make powder or oral liquid.

Embodiment 2

[0172] Take 15kg of Xiawu, 15kg of turmeric, and 15kg of clove, add 10 times the amount of 85% ethanol, extract twice for 1.5 hours each time, filter the extract, combine, concentrate, and add conventional pharmaceutical excipients to make a mixture or oral liquid.

Embodiment 3

[0174] According to the weight ratio, take 5kg of cloves, extract volatile oil, and clathrate with β-cyclodextrin; take 30kg of Xiawu, 15kg of turmeric, add 10 times the amount of water, decoct and extract twice, each time for 0.5 hours, filter the extract, and combine , concentrated, vacuum-dried, adding clove β-cyclodextrin inclusion complex, adding conventional pharmaceutical excipients in traditional Chinese medicine preparations, and making tablets.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating dementia and a preparation method thereof. The composition is characterized by consisting of the following traditional Chinese medicine raw materials in parts by weight: 1-30 parts of rhizoma corydalis decumbentis, 1-30 parts of rhizoma curcumae longae and 1-30 parts of flos caryophylli. According to the traditional Chinese medicine composition and the preparation method thereof, the active ingredients of the composition are extracted by a reasonable process; the composition is made into multiple dosage forms and is good in safety; moreover, the composition can effectively reduce the brain tissue injury caused by cerebral ischemia and obviously alleviate the dementia symptoms, and realizes a remarkable effect in a process of preventing and treating vascular dementia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for treating dementia and a preparation method thereof. Background technique [0002] Dementia actually refers to the decline of brain function, especially the overall decline of intelligence-related functions, and it will decline to a certain extent. Dementia related to cerebrovascular factors is collectively referred to as vascular dementia. The most common cause of vascular dementia is cerebral arteriosclerosis. The lipid metabolism disorder in the body leads to fat accumulation on the blood vessel wall, which narrows the vascular lumen and reduces the elasticity of the blood vessel. In severe cases, it is completely blocked, resulting in insufficient blood supply to the brain tissue, and finally brain cell necrosis. Tissue softens, and many infarcts and softening lesions appear in the brain. Therefore, cerebrovascular demen...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P25/28
Inventor 萧伟王振中曹亮陶晓倩丁岗章晨峰
Owner JIANGSU KANION PHARMA CO LTD
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