Azelnidipine preparation with combination of two disintegrating agents and preparation method of azelnidipine preparation
A technology of azedipine and disintegrant, which is applied in the field of azedipine preparations and its preparation, can solve the problems of undisclosed dosage forms for rapid release of drugs, and does not involve dissolution curve fitting, so as to achieve the effect of saving manpower and material resources
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Embodiment A
[0025]
[0026] Preparation process: pass the azedipine, lactose, microcrystalline cellulose, carmellose calcium and low-substituted hydroxypropyl cellulose in the prescription through a 60-mesh sieve twice, mix well, add magnesium stearate, mix well Compressed into tablets.
Embodiment B
[0028]
[0029]
[0030] Preparation process: pass the azelnidipine, mannitol, carmellose calcium, low-substituted hydroxypropyl cellulose and micropowder silica gel in the prescription twice through a 60-mesh sieve, mix well, add magnesium stearate, mix well Pressed into tablets.
Embodiment C
[0032]
[0033] Preparation process: pass the azedipine, microcrystalline cellulose, mannitol, carmellose calcium and low-substituted hydroxypropyl cellulose in the prescription through a 60-mesh sieve twice, mix well, add magnesium stearate, mix well Compressed into tablets.
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