Formula composition and medicinal preparation with effects of increasing bone density and treating bone joint pain, preparation method of medicinal preparation and application of formula composition
A technology for increasing bone density and pharmaceutical preparations, applied in the directions of medical preparations containing active ingredients, food preparation, and drug combinations, etc. The effect of treating joint pain
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Embodiment 1
[0028] This embodiment provides a formula composition with the effects of increasing bone density and treating bone and joint pain, which can increase human bone density, prevent osteoporosis, and treat bone and joint pain. The formulation composition of the present embodiment is made up of the raw material of following weight portion:
[0029] D-glucosamine sulfate potassium salt 60-90 parts, calcium carbonate 35-65 parts, bone collagen 10-40 parts, psoraleae extract 10-25 parts, casein phosphopeptide 2-8 parts.
[0030] Among them, D-glucosamine sulfate potassium salt, also known as glucosamine sulfate potassium salt, the English name is "N-Sulfo-glucosamine potassium salt", we found in the study that glucosamine and chitosan oligosaccharides have a strong effect on bone turnover It has obvious inhibitory effect, can improve the ability of bone reconstruction, and has obvious antagonism effect on osteoporosis caused by ovariectomy.
[0031] In the comparative experiments of...
Embodiment 2
[0044] Embodiment 2 Provides a preferred formulation composition with the effect of increasing bone density and treating bone and joint pain on the basis of Embodiment 1, which consists of the following raw materials in parts by weight: 75 parts of D-glucosamine sulfate potassium salt, calcium carbonate 50 parts, collagen 25 parts, psoraleae extract 15 parts, casein phosphopeptide 4 parts.
[0045] In a preferred embodiment, the psoralen extract contains psoralen greater than or equal to 1% by weight.
[0046] The formulation composition described in this example can be prepared by mixing various raw materials.
[0047] The formula composition with the effect of increasing bone density can be taken orally after being prepared as a pharmaceutical preparation, and the recommended dosage for human body is 4g / person / day.
[0048] In this example, D-glucosamine sulfate potassium salt, calcium carbonate, collagen, psoraleae extract and casein phosphopeptide are used together in the...
Embodiment 3
[0050] Embodiment 3 provides a pharmaceutical preparation based on the formulation composition described in Embodiment 1, that is, the formulation composition is composed of the following raw materials in parts by weight:
[0051] D-glucosamine sulfate potassium salt 60-90 parts, calcium carbonate 35-65 parts, bone collagen 10-40 parts, psoraleae extract 10-25 parts, casein phosphopeptide 2-8 parts.
[0052] The pharmaceutical preparation of this embodiment is composed of the raw materials of the above formula composition and solid pharmaceutical auxiliary materials; the weight of the solid pharmaceutical auxiliary materials does not exceed 25% of the weight of the pharmaceutical preparation.
[0053] Specifically, the pharmaceutical preparation of this example uses the formula composition with the effect of increasing bone density described in Example 1 as a raw material, combined with solid pharmaceutical excipients to form a solid form of pharmaceutical preparation, which is...
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