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Compound medicine for treating hypoferric anemia and preparation method thereof

An iron-deficiency anemia, compound technology, applied in drug delivery, drug combination, medical preparations containing active ingredients, etc., can solve problems such as iron malabsorption, achieve long-lasting effect, consolidated curative effect, and no rebound effect

Inactive Publication Date: 2013-12-11
费海荣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

2. Iron malabsorption: iron deficiency anemia due to iron absorption disorder is relatively rare

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1: The preparation method of the compound medicine for the treatment of iron deficiency anemia comprises the following steps,

[0028] 1) Pre-treatment: ① Grind jujube, saponin, rehmannia glutinosa, hawthorn, and rehmannia glutinosa, and pass through a 60-mesh sieve; ② add sodium carboxymethyl starch to purified water to make 10% sodium starch glycolate slurry;

[0029] 2) Mixing: jujube 150-200, saponin 80-300, rehmannia 37-41, astragalus 70-85, hawthorn 35-50, cork 99-121, scutellaria 76-83, ferrous fumarate 3-50 5. Sucrose 67-86, dextrin 35-65, microcrystalline cellulose 90-110, sodium starch glycolate 58-71, copovidone 54-66, silicon dioxide 21-26, magnesium stearate 9-11 Put the above-mentioned components in a mixer and mix them for 10-20 minutes;

[0030] 3) Granulation: add an appropriate amount of 10% carboxymethyl starch sodium slurry to make soft materials, and then use a 12-mesh screen to make granules;

[0031] 4) Drying: Use a fluidized bed for...

Embodiment 2

[0037] Embodiment 2: Take 150-200 pieces of jujube, 80-300 pieces of saponin, 37-41 pieces of rehmannia root, 70-85 pieces of astragalus, 35-50 pieces of hawthorn, 99-121 pieces of cork phellodendron, 76-83 pieces of baicalin, and 3-30 pieces of ferrous fumarate. 5. Sucrose 67-86, dextrin 35-65, microcrystalline cellulose 90-110, sodium starch glycolate 58-71, copovidone 54-66, silicon dioxide 21-26, magnesium stearate 9-11 Carry out pretreatment; Get hypromellose 12.6~15.4, talcum powder 3.6~4.4, triacetin 1.8~2.2 to make coating agent; Its preparation method is as described in Example 1, abbreviated, according to Example 1 Preparation method, namely the compound drug B for the treatment of iron deficiency anemia.

Embodiment 3

[0038]Embodiment 3: Take 150-200 pieces of jujube, 80-300 pieces of saponin, 37-41 pieces of rehmannia root, 70-85 pieces of astragalus, 35-50 pieces of hawthorn, 99-121 pieces of Phellodendron cortex, 76-83 pieces of baicalin, and 3-30 pieces of ferrous fumarate. 5. Sucrose 67-86, dextrin 35-65, microcrystalline cellulose 90-110, sodium starch glycolate 58-71, copovidone 54-66, silicon dioxide 21-26, magnesium stearate 9-11 Carry out pretreatment; Get hypromellose 12.6~15.4, talcum powder 3.6~4.4, triacetin 1.8~2.2 to make coating agent; Its preparation method is as described in Example 1, abbreviated, according to Example 1 Preparation method, namely the compound drug C for the treatment of iron deficiency anemia.

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PUM

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Abstract

The invention relates to a compound medicine for treating hypoferric anemia and a preparation method thereof. The compound medicine for treating the hypoferric anemia is prepared from the following raw materials and auxiliary materials in parts by weight: 150-200 parts of Chinese-date, 80-300 parts of melanterite, 37-41 parts of dried rehmannia root, 70-85 parts of astragalus membranaceus, 35-50 parts of hawthorn, 99-121 parts of golden cypress, 76-83 parts of scutellaria baicalensis, 3-5 parts of ferrous fumarate, 67-86 parts of cane sugar, 35-65 parts of dextrin, 90-110 parts of microcrystalline cellulose, 58-71 parts of hydroxyl methyl starch sodium,54-66 parts of copovidone, 21-26 parts of silica, 9-11 parts of magnesium stearate and 18-22 parts of transparent film coating materials. The compound medicine for treating the hypoferric anemia and the preparation method thereof disclosed by the invention have the advantages of being fast to take effect, non-resilient in effect, consolidated in curative effect, lasting in action and the like by combination rationality of the components, and are widely applied to disease control and treatment of aplastic anemia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound composition preparation, in particular to a compound capsule for treating iron deficiency anemia and a preparation method thereof. Background technique [0002] Iron deficiency anemia (iron deficiency anemia, IDA) is a common anemia caused by the lack of iron in the body and affects the synthesis of hemoglobin. Both concentration and serum transferrin saturation were decreased. Typical cases of anemia are small cell hypochromic type. Iron-deficiency anemia is a common type of anemia that is prevalent all over the world. The incidence of this anemia is very high in women of childbearing age and infants and young children. The clinical epidemiological survey of high-risk groups in Shanghai shows that the prevalence rates of iron deficiency anemia in menstrual women, pregnant women and adolescents are 11.39%, 9.28% and 9.84% respectively. %, the prevalence of iron deficiency was 43.3%, 66...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/36A61P7/06
Inventor 费海荣李颖王媛媛王展
Owner 费海荣
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