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Compound medicine for preventing and treating hemophilia

A hemophilia and compound technology, applied in blood diseases, drug combinations, medical formulas, etc., can solve the problems of heavy economic burden and high cost of blood coagulation factors, and achieve the effect of low price, short course of treatment and quick effect

Inactive Publication Date: 2014-05-14
韩为
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the most commonly used treatment method is blood coagulation factor transfusion, but this method can only be maintained for a short period of time, and the coagulation factor in the blood will decrease after a period of time. Generally speaking, the financial burden is heavy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036]Example 1: Cortex Moutan 33, Rehmannia glutinosa 23, Radix Paeoniae Rubra 18, Dodder 17, Antler velvet 10, Buffalo horn 10, Arborvitae leaves 14, Poria cocos 10, Eclipta 23, Ligustrum lucidum 9, Astragalus 15, Codonopsis 13 , Shouwu 8, Comfrey 11, Angelica 20, Achyranthes bidentata 4, Longan 15, Woody Fragrant 9, Polygala 18, Agrimony 8, Panax notoginseng 15 The weight ratio of each component is weighed, and adding 35%~ 50% lactose, gelatin, microcrystalline cellulose, lubricant, magnesium stearate, fully stirred and mixed to form granules, dried at 60-70°C for 2-4 hours and pressed into tablets to obtain the compound drug tablet.

Embodiment 2

[0037] Example 2: Cortex Moutan 27, Rehmannia glutinosa 35, Radix Paeoniae Rubra 13, Cuscuta 17, Deer Antler 5, Buffalo horn 20, Arborvitae leaves 7, Poria cocos 15, Eclipta chinensis 18, Ligustrum lucidum 12, Astragalus 6, Codonopsis 17 , Shouwu 3, Comfrey 13, Angelica 16, Achyranthes bidentata 9, Longan 11, Woody Fragrance 12, Polygala 15, Agrimony 13, Panax notoginseng 10 The weight ratio of each component is weighed, and adding 35%~ 50% starch, hydroxypropyl methyl cellulose, sodium carboxymethyl starch, propyl methyl cellulose, fully stirred and mixed to form granules, and the prepared wet granules were dried at 60-70°C for 2-4 hours, and then Fill it into the empty plastic shell to obtain the compound drug capsule.

Embodiment 3

[0038] Example 3: Cortex Moutan 30, Rehmannia glutinosa 28, Paeoniae Rubra 15, Dodder 15, Antler velvet 8, Buffalo horn 16, Arborvitae leaves 10, Poria cocos 13, Eclipta 20, Ligustrum lucidum 10, Astragalus 12, Codonopsis 16 , Shouwu 6, Comfrey 11, Angelica 18, Achyranthes bidentata 7, Longan 13, Woody Fragrance 11, Polygala 17, Agrimony 9, Panax notoginseng 12 Weigh each component, add 60%~ 80% water-ethanol mixed solvent and sorbitol, mix well, add activated carbon to decolorize, filter, filter with a micro air filter membrane less than 0.45μm, after ultrafiltration, potting, sterilize at 100°C for 30-60h, so that each mL contains 500 mg of the composition; or divide the obtained filtrate according to the standard, freeze-dry under vacuum conditions, and obtain the compound medicine freeze-dried powder injection.

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PUM

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Abstract

The invention relates to a compound medicine for preventing and treating hemophilia. The compound medicine for preventing and treating hemophilia is prepared from the following components in parts by weight: 27-33 parts of moutan barks, 23-35 parts of rehmannia, 13-18 parts of roots of common peony, 12-17 parts of semen Cuscutae, 5-10 parts of savatier monochasma herb, 10-20 parts of cornu bubali, 7-14 parts of cacumen biotae, 10-15 parts of poria cocos, 18-23 parts of eclipta, 9-12 parts of glossy privet fruits, 6-15 parts of astragalus membranaceus, 13-17 parts of codonopsis pilosula, 3-8 parts of prepared fleece flower roots, 11-13 parts of lithospermum, 16-20 parts of angelica sinensis, 4-9 parts of radix achyranthis bidentatae, 11-15 parts of longan aril, 9-12 parts of elecampane, 15-18 parts of polygala tenuifolia, 8-13 parts of hairyvein agrimony and 10-15 parts of pseudo-ginseng. The compound medicine provided by the invention has the advantages of short treatment course, good curative effect and the like through reasonable compatibility of the effective components and auxiliary components and mutual complementation and coordination of functions, is blended by pure natural dried medicinal herbs and is free from side effects, dependence and resistance to drugs.

Description

technical field [0001] The invention relates to a compound medicine for preventing and treating hemophilia. Background technique [0002] Hemophilia (hemophilia) is a group of relatively common hereditary bleeding disorders with the characteristics of X-linked recessive inheritance. According to the lack of coagulation factors, it can be divided into FVIII deficiency and FIX deficiency. Due to FVIII or FIX The reduction of procoagulant activity leads to thromboplastin generation disorder, prolongation of coagulation time, and abnormal bleeding tendency after minor trauma for life. The specific manifestations are juvenile onset, spontaneous or mild traumatic bleeding, hematoma formation and joint bleeding. Due to the lack of a certain coagulation factor in the patient's blood plasma, after the patient's blood vessel ruptures, the blood is less likely to coagulate than normal people, so more blood will flow out. Bleeding from superficial wounds is usually not serious, wherea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P7/00A61P7/04A61K35/32
Inventor 徐艳艳
Owner 韩为
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