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Cu and Zn-rh SOD cosmetic composition for removing freckle, whitening skin and resisting wrinkles

A cosmetic composition and freckle-removing and whitening technology, applied in the direction of cosmetics, cosmetic preparations, dressing preparations, etc., can solve the problems of not easy to penetrate the skin stratum corneum, poor thermal stability, short half-life, etc., to inhibit the synthesis of melanin, maintain Long-lasting, delicate skin effect

Active Publication Date: 2013-12-04
上海玉华生命科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the use of SOD as an active enzyme as a cosmetic ingredient is affected by many factors, such as poor thermal stability, easy inactivation, and short half-life; the molecular weight is around 32,000, and it is difficult to penetrate the stratum corneum of the skin, etc.

Method used

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  • Cu and Zn-rh SOD cosmetic composition for removing freckle, whitening skin and resisting wrinkles

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1. Preparation of Chinese herbal medicine extracts

[0021] The formula (weight ratio) is as follows in Table 1:

[0022] Extract 1 extract 2 Extract 3 extract 4 Saffron 5 3 1 5 Salvia 3 6 8 2 Licorice 8 5 5 10 Amla 4 3 6 5 White Poria 5 3 2 4

[0023] white scorpion 6 8 1 3 angelica 3 5 5 1

[0024] The preparation method of the Chinese herbal medicine extract (abbreviation: extract) is as follows: saffron, salvia, licorice, emblica, tuckahoe, white radish, angelica and other Chinese herbal medicine pieces are pulverized respectively, then sieved with 40 meshes, and then added 8 times respectively. The ethanol concentration of deionized water in parts by weight of traditional Chinese medicine is 50%-85%; then soak at 25°C for more than 10 hours; perform low-temperature (<80°C) ultrasonic extraction for 4 hours, take the supernatant, centrifuge, After filtering, reflu...

Embodiment 2

[0025] Embodiment 2. Preparation of SOD cosmetic for freckle, whitening and anti-wrinkle

[0026] According to the 10000g product, the content of each component is listed in Table 2 (g)

[0027] Table 2

[0028] emulsifying base Chinese herbal extract transdermal absorption enhancer Enzyme protection agent Deionized water SOD 1 5000 3000 300 100 1600 0.2 2 8000 1000 100 500 198 2 3 6000 2000 200 500 1300 0.4 4 6000 1000 200 200 2600 0.4 5 6000 1000 200 200 2600 0.4 6 6000 1000 200 200 2600 0.4 7 6000 1000 200 200 2600 0.4 8 6000 1000 200 200 2600 0.4

[0029] The Chinese herbal medicine extracts are the extracts 1-4 prepared in Example 1, wherein the No. 1 cosmetic is the extract 3, the No. 2 cosmetic is the extract 4, the No. 3 cosmetic is the extract 1, and the No. 4-8 cosmetic is the extract 1. Extract 2.

[0030] SOD: recombinant human copper-zinc superoxide dismut...

Embodiment 3

[0039] Example 3. Long-term enzyme activity detection of SOD in cosmetics

[0040]Cosmetics No. 3-8 (SOD dosage: 200U / g) prepared in Example 2 were subjected to pyrogallol autoxidation at different time points (Zhang Hong, Tan Zhujun "Journal of Inner Mongolia University: Natural Science Edition" 2002 Page 677-681 of Issue 6) to detect SOD enzyme activity, the results are shown in Table 3.

[0041] table 3

[0042]

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PUM

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Abstract

The invention relates to the technical field of cosmetics, in particular to a Cu, Zn-rh SOD cosmetic composition for removing freckle, whitening skin and resisting wrinkles. The cosmetic composition comprises the following components by mass percent: 50-80% of emulsion matrix, 10-30% of a Chinese herb extract, 1-3% of skin penetration enhancer, 1-5% of an enzyme activity protective agent, and 100% of 100-1,000 u / g Cu, Zn-rh SOD and deionized water. The Chinese herb extract comprises the following Chinese herbal medicines in parts by weight: 1-5 parts of saffron crocus, 2-8 parts of salvia miltiorrhiza, 5-10 parts of liquorice, 3-6 parts of emblic leafflower fruit, 2-5 parts of white poria, 1-8 parts of radix ampelopsis and 1-5 parts of angelica sinensis. The cosmetic composition can remove freckles and colored spots on the skin to enable the skin to be relatively fine, smooth, white and resilient, meets the daily skin-care requirements of face skin whitening, freckle removing and wrinkles resisting of people, and is a novel safe high-quality cosmetic.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a Cu, Zn-rhSOD cosmetic composition for freckle, whitening and anti-wrinkle. Background technique [0002] As we all know, due to ultraviolet rays in the sun and many other factors in life, such as computer radiation, smoking and drinking, stress, junk food, etc., will increase the production of free radicals in the body, accelerate the oxidation of cells, and lead to accelerated skin aging, especially It is ultraviolet rays. After it penetrates into the skin, it will generate harmful free radicals. These free radicals will increase the number of epithelial lipid peroxides (LPO), destroy the collagen and elastic fibers of the skin, and stimulate melanocytes. Increase the secretion of melanin, resulting in dry and loose skin, loss of elasticity, wrinkles, yellowing and blackening, pigmentation or freckles, etc. [0003] The application of SOD in skin care products mainly includ...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K8/66A61Q19/00A61Q19/02A61Q19/08
Inventor 刘霞
Owner 上海玉华生命科技发展有限公司
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