Medicine composition for treating recurrent respiratory tract infection of children
A composition and respiratory technology, applied in the field of medicine, can solve problems such as easy repetition, achieve long-lasting drug effect, simple and feasible preparation process, and no obvious side effects
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Embodiment 1
[0022] Prepare 1000ml pharmaceutical composition of the present invention
[0023] A pharmaceutical composition for recurrent respiratory tract infection in children, characterized in that the main drug is added to the pharmaceutical auxiliary material, suspended, configured into a solution, sterilized, and packaged, and the main drug is prepared from the following raw materials : Ibuprofen 5g, Bupleurum 20g, Coptidis 20g, Chinese yam 18g, Bamboo leaves 15 parts, Liangmianzhen 15g, Astragalus 15g, Pinellia 12g, Trichosanthes 10g, Angelica dahurica 10g, Safflower 5g, Curcuma 5g, Pomegranate peel 3g , licorice 3g.
[0024] The preparation method is:
[0025] 1 Preparation of traditional Chinese medicine extract:
[0026] Take 20g of Bupleurum, 20g of Coptidis, 18g of Chinese yam, 15g of bamboo leaves, 15g of double-faced needles, 15g of astragalus, 12g of Pinellia, 10g of Trichosanthes, 10g of Angelica dahurica, 5g of safflower, 5g of turmeric, 3g of pomegranate peel, 3g of li...
Embodiment 3
[0034] 1. Toxicity test:
[0035] In this experiment, healthy SD rats were used, and the dose gradient of the drug prepared in Example 1 was administered orally at 0.1ml / kg and 0.5ml / kg, and the drug was administered continuously for 30 days. Animal growth status, activity diet, hematology, blood biochemistry, organ tissue structure and urine routine were not significantly affected, indicating that the clinical medication is safe and reliable.
[0036] 2. Analgesic experiment:
[0037] The effect on the writhing reaction induced by acetic acid in BALB / c mice: 60 BALB / c mice, half male and half male, with an average body weight of 19.5 g, were randomly divided into two groups, namely the normal saline group and the drug group of Example 1; Administer once a day, the dose is 0.25ml / kg (the experimental group is given the drug, the control group is given the same weight of normal saline), and it is given by intragastric administration for 3 consecutive days. Acetic acid 0.2ml / m...
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