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Natural drug extract and preparation method thereof

A technology of natural medicines and extracts, applied in drug combinations, pharmaceutical formulas, anti-tumor drugs, etc., can solve the problems of patients with dehydration, acid-base balance imbalance, malnutrition, etc., and achieve increased inhibition, enhanced inhibition, and good side effects Effect

Inactive Publication Date: 2013-10-09
石强
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AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural drug extract and preparation method thereof

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Effect test

Embodiment approach

[0035] The first step: preparation of various extracts

[0036] (1) Preparation of concentrated extract of cardamom clove decoction

[0037] Take cardamom and clove according to the compatibility ratio of 1:1, soak in distilled water, heat and decoct, filter with silk cloth, add distilled water to the dregs, soak in the same way, decoct, filter, mix the two filtrates, heat and concentrate, and ultrafilter Membrane filtration, drying under reduced pressure, that is.

[0038] (2) Preparation of ethyl acetate extract of cardamom

[0039] Grind the dried cardamom, sieve, heat and reflux extraction with 70% ethanol for 3 times, combine the solvents, recover the solvent under reduced pressure to obtain a dry extract, dilute the extract with hot water to form a suspension, put it at room temperature, and extract with ethyl acetate , recovery of solvent, drying, crushing, sieving, that is.

[0040] (3) Preparation of clove ethanol extract

[0041] Dried cloves, crushed, sieved, so...

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Abstract

The invention relates to a natural drug extract and a preparation method thereof. The natural drug extract consists of an extract prepared by decocting and concentrating amomum kravanh and clove in water, amomum kravanh ethyl acetate extract, clove ethanol extract and eugenol by a ratio of (1-4):(3-5):(2-6):(5-9). The composition has an extremely good treatment effect on diarrhea related with cancer chemotherapy and also has a synergism effect on cancer chemotherapy.

Description

technical field [0001] The present invention relates to a natural medicine extract, more specifically to a natural medicine extract composed of cardamom clove decoction concentrated extract, cardamom ethyl acetate extract, clove ethanol extract and eugenol. The preparation method of the medicine extract and the use of the natural medicine extract in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated diarrhea. In rec...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61P35/00A61P1/12A61K31/085
Inventor 石强
Owner 石强
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